Christine E Canman

 Christine E. Canman
Associate Professor of Pharmacology
Medical School
[email protected]
Available to mentor
Christine E Canman
Christine E. Canman
Associate Professor
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    • Recent Publications

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    • Presentation
      Academy of Educators: Synchronous vs. Asynchronous Lectures Panel
      Canman C, Tai A, Hortsch M. 2022 Oct 17;
    • Journal Article
      Which holds the key to BRCAness: Inability to repair the break, protect the fork, or prevent the gap?
      Canman CE. Cancer Research, 2021 Mar 1; 81 (5): 1214 - 1215. DOI:10.1158/0008-5472.CAN-20-4340
      PMID: 33822743
    • Journal Article
      Combinatorial efficacy of olaparib with radiation and ATR inhibitor requires PARP1 protein in homologous recombination–proficient pancreatic cancer
      Parsels LA, Engelke CG, Parsels J, Flanagan SA, Zhang Q, Tanska D, Wahl DR, Canman CE, Lawrence TS, Morgan MA. Molecular Cancer Therapeutics, 2021 Feb 1; 20 (2): 263 - 273. DOI:10.1158/1535-7163.MCT-20-0365
      PMID: 33268569
    • Journal Article
      Replication Stress: An Achilles' Heel of Glioma Cancer Stem-like Cells
      Morgan MA, Canman CE. American Association for Cancer Research (AACR), 2018 Nov 29; 78: 6713 - 6716.
    • Journal Article
      A single aspartate mutation in the conserved catalytic site of Rev3L generates a hypomorphic phenotype in vivo and in vitro
      Fritzen R, Delbos F, De Smet A, Palancade B, Canman CE, Aoufouchi S, Weill JC, Reynaud CA, Storck S. DNA Repair, 2016 Oct 1; 46: 37 - 46. DOI:10.1016/j.dnarep.2016.07.002
      PMID: 27481099
    • Journal Article
      ATDC/TRIM29 phosphorylation by ATM/MAPKAP kinase 2 mediates radioresistance in pancreatic cancer cells
      Wang L, Yang H, Palmbos PL, Ney G, Detzler TA, Coleman D, Leflein J, Davis M, Zhang M, Tang W, Hicks JK, Helchowski CM, Prasad J, Lawrence TS, Xu L, Yu X, Canman CE, Ljungman M, Simeone DM. Cancer Research, 2014 Mar 15; 74 (6): 1778 - 1788. DOI:10.1158/0008-5472.CAN-13-2289
      PMID: 24469230
    • Journal Article
      PCAT-1, a long noncoding RNA, regulates BRCA2 and controls homologous recombination in cancer
      Prensner JR, Chen W, Iyer MK, Cao Q, Ma T, Han S, Sahu A, Malik R, Wilder-Romans K, Navone N, Logothetis CJ, Araujo JC, Pisters LL, Tewari AK, Canman CE, Knudsen KE, Kitabayashi N, Rubin MA, Demichelis F, Lawrence TS, Chinnaiyan AM, Feng FY. Cancer Research, 2014 Mar 15; 74 (6): 1651 - 1660. DOI:10.1158/0008-5472.CAN-13-3159
      PMID: 24473064
    • Journal Article
      A small molecule inhibitor of monoubiquitinated proliferating cell nuclear antigen (PCNA) inhibits repair of interstrand DNA cross-link, enhances DNA double strand break, and sensitizes cancer cells to cisplatin
      Inoue A, Kikuchi S, Hishiki A, Shao Y, Heath R, Evison BJ, Actis M, Canman CE, Hashimoto H, Fujii N. Journal of Biological Chemistry, 2014 Mar 7; 289 (10): 7109 - 7120. DOI:10.1074/jbc.M113.520429
      PMID: 24474685