Stewart C Wang, MD, PhD
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About
I completed my Ph.D. training in molecular immunology before joining the surgical faculty at UM in 1995 with an appointment as the Director of Research for the Trauma Burn Center. In this role, I was asked to become one of the founding principal investigators (PI) for the multidisciplinary Crash Injury Research Engineering Network (CIREN), a government-industry-academia research consortium. I led the CIREN team at UM for 14 years and served 3 years as lead PI of the entire consortium. I also served as Associate Chairman of Surgery for Research during the realignment to the NIH Roadmap.
Center Memberships
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Center MemberInstitute for Healthcare Policy and Innovation
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Center MemberUniversity of Michigan Injury Prevention Center
Research Overview
I endeavored to be a local role model for the NIH Roadmap’s integrated vision by generating opportunities in three main areas: new pathways to discovery, research teams of the future, and re-engineering the clinical research enterprise. Analytic morphomics is the term I created to describe the innovative high-throughput, highly automated, anatomically-indexed processing of 3D medical imaging data that I developed to support my interdisciplinary translational research. It is designed to take rapid advantage of advances in computation and medical imaging as well as the statistical techniques developed for genomic and proteomic analysis. Analytic morphomics also provides a strong platform for personalized/precision medical care.
Recent Publications
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Ejima S, Zhang P, Cunningham K, Wang S. SAE International Journal of Transportation Safety, 2026 May 4; 14 (1):Journal ArticleValidation of Vehicle-Based Injury Severity Prediction Using Crash Telemetry Data
DOI:10.4271/09-14-01-0009 -
Chiu C-H, Lin J, Zhang P, Chang AC, Derstine BA, Ross BE, Enchakalody B, Shah NV, Liu Y-H, Wang SC, Chao Y-K. J Cardiothorac Surg, 2026 Apr 12;Journal ArticleThe effects of neoadjuvant chemoradiotherapy-related frailty by analytic morphomics in esophageal cancer.
DOI:10.1186/s13019-026-03959-4 PMID: 41965829 -
Derstine BA, Holcombe SA, Chen VL, Pai MP, Sullivan JA, Wang SC, Su GL. Abdominal Radiology, 2026 Feb 1; 51 (2): 991 - 1003.Journal ArticleQuantification of hepatic steatosis on post-contrast computed tomography scans using artificial intelligence tools
DOI:10.1007/s00261-025-05137-x PMID: 40715517 -
Russo RM, Ruby J, Derstine BA, Holcombe S, Eliason JL, Wang SC. Journal of Trauma and Acute Care Surgery, 2026 Feb 1; 100 (2): e17Journal ArticleReply to Letter to the Editor, re: Morphometric analysis for resuscitative endovascular balloon occlusion of the aorta in women
DOI:10.1097/TA.0000000000004814 PMID: 41259073 -
Gunchick V, Brown E, Wang S, Su G, Sahai V. Journal of Clinical Oncology, 2026 Jan 14; 44 (2_suppl): 781 - 781.Proceeding / Abstract / PosterLongitudinal morphomics and metabolomics as metastatic pancreatic cancer prognosticators.
DOI:10.1200/jco.2026.44.2_suppl.781 -
Dougherty JM, Kurth AE, Parviz S, Kozlowski M, Edwards D, Wang SC, Sangji NF. J Burn Care Res, 2025 Sep 19; 46 (5): 935 - 939.Journal ArticleThe State of Michigan Burn Mass Casualty Incident Surge Plan: Leveraging Trauma Centers as Burn Surge Facilities.
DOI:10.1093/jbcr/iraf077 PMID: 40442033 -
Tseng WH-S, Huang S-C, Wang SC, Lin J, Zhang P, Liu Y-C, Chao Y-K, Chiu C-H. World J Gastrointest Surg, 2025 Aug 27; 17 (8): 108600Journal ArticleMorphomics in esophageal cancer: Validation and association with muscular and cardiorespiratory fitness.
DOI:10.4240/wjgs.v17.i8.108600 PMID: PMC12427075 -
Chan E, Bryan D, Lin J, Madariaga ML, Derstine B, Donington J, Sanchez P, Wang S, Ferguson M. Diseases of the Esophagus, 2025 Aug 15; 38 (Supplement_1): doaf061.282Journal Article049. INDUCTION THERAPY FOR ESOPHAGEAL CANCER SIGNIFICANTLY ALTERS CT-DERIVED BODY COMPOSITION AND SURGICAL RISK
DOI:10.1093/dote/doaf061.282
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