Michael M Wang
Professor of Neurology
Professor of Molecular and Integrative Physiology
Medical School
[email protected]
Available to mentor
Michael M Wang
Professor
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Center Memberships
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Center MemberSamuel and Jean Frankel Cardiovascular Center
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Center MemberCenter for Cell Plasticity and Organ Design
Recent Publications
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Cartee NMP, Lee SJ, Wu E, Sukpraphrute R, Sukpraphrute C, Greenbaum J, Wang MM. Journal of Biological Chemistry, 2025 Mar 1; 301 (3):Journal ArticleLight-chain split luciferase assay implicates pathological NOTCH3 thiol reactivity in inherited cerebral small vessel disease
DOI:10.1016/j.jbc.2025.108224 PMID: 39864627 -
Keller JN, Radabaugh H, Karvelas N, Fitzsimons S, Treiman S, Palafox MF, McDonnell L, Quiroz YT, Lopera FJ, Banerjee D, Wang MM, Arboleda-Velasquez JF, Meschia JF, Ferguson AR, Elahi FM. 2024 Mar 31; bioRxiv,PreprintPlasma Proteomics of Genetic Brain Arteriosclerosis and Dementia Syndrome Identifies Signatures of Fibrosis, Angiogenesis, and Metabolic Alterations
DOI:10.1101/2024.03.28.587249 -
Romay MC, Knutsen RH, Ma F, Mompeón A, Hernandez GE, Salvador J, Mirkov S, Batra A, Sullivan DP, Procissi D, Buchanan S, Kronquist E, Ferrante EA, Muller WA, Walshon J, Steffens A, McCortney K, Horbinski C, Tournier‑Lasserve E, Sonabend AM, Sorond FA, Wang MM, Boehm M, Kozel BA, Iruela-Arispe ML. Journal of Clinical Investigation, 2024 Jan 16; 134 (2):Journal ArticleAge-related loss of Notch3 underlies brain vascular contractility deficiencies, glymphatic dysfunction, and neurodegeneration in mice
DOI:10.1172/JCI166134 PMID: 38015629 -
Lee SJ, Gasche MB, Burrows CJ, Kondepudi A, Zhang X, Wang MM. Scientific Reports, 2023 Dec 1; 13 (1):Journal ArticlePreferential rabbit antibody responses to C-termini of NOTCH3 peptide immunogens
DOI:10.1038/s41598-023-36067-7 PMID: 37280231 -
Meschia JF, Worrall BB, Elahi FM, Ross OA, Wang MM, Goldstein ED, Rost NS, Majersik JJ, Gutierrez J. Stroke, 2023 Oct 1; 54 (10): E452 - E464.Journal ArticleManagement of Inherited CNS Small Vessel Diseases: The CADASIL Example: A Scientific Statement from the American Heart Association
DOI:10.1161/STR.0000000000000444 PMID: 37602377 -
Lee SJ, Zhang X, Wu E, Sukpraphrute R, Sukpraphrute C, Ye A, Wang MM. Journal of Biological Chemistry, 2023 Jun 1; 299 (6):Journal ArticleStructural changes in NOTCH3 induced by CADASIL mutations: Role of cysteine and non-cysteine alterations
DOI:10.1016/j.jbc.2023.104838 PMID: 37209821 -
Xu G, Mihaylova T, Li D, Tian F, Farrehi PM, Parent JM, Mashour GA, Wang MM, Borjigin J. Proceedings of the National Academy of Sciences of the United States of America, 2024 Jan 22; 120 (19):Journal ArticleSurge of neurophysiological coupling and connectivity of gamma oscillations in the dying human brain
DOI:10.1073/PNAS.2216268120 -
Elahi FM, Wang MM, Meschia JF. Stroke, 2023 Mar 1; 54 (3): 648 - 660.Journal ArticleCerebral Small Vessel Disease-Related Dementia: More Questions Than Answers
DOI:10.1161/STROKEAHA.122.038265 PMID: 36848423