Sebastian K Zoellner
John G Searle Associate Professor of Biostatistics
Professor of Biostatistics
School of Public Health
Professor of Psychiatry
Medical School
Available to mentor
Sebastian K Zoellner
Professor
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Center Memberships
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Center MemberEisenberg Family Depression Center
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Center MemberAI and Digital Health Innovation
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Center MemberCenter for Computational Medicine and Bioinformatics
Recent Publications
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Huang YJ, Kurniansyah N, Goodman MO, Spitzer BW, Wang J, Stilp A, Laurie C, de Vries PS, Chen H, Min YI, Sims M, Peloso GM, Guo X, Bis JC, Brody JA, Raffield LM, Smith JA, Zhao W, Rotter JI, Rich SS, Redline S, Fornage M, Kaplan R, Franceschini N, Levy D, Morrison AC, Boerwinkle E, Smith NL, Kooperberg C, Psaty BM, Zöllner S, de Vries PS, Sofer T. Nature Communications, 2026 Dec 1; 17 (1):Journal ArticleAdmixture-informed polygenic risk reporting using the ePRS framework
DOI:10.1038/s41467-026-72457-x PMID: 42062286 -
Orchard P, Blackwell TW, Kachuri L, Castaldi PJ, Cho MH, Christenson SA, Durda P, Gabriel S, Hersh CP, Huntsman S, Hwang S, Joehanes R, Johnson M, Li X, Lin H, Liu CT, Liu Y, Mak ACY, Manichaikul AW, Paik DT, Saferali A, Smith JD, Taylor KD, Tracy RP, Wang J, Wang M, Weinstock JS, Weiss J, Wheeler HE, Zhou Y, Zöllner S, Wu JC, Mestroni L, Graw S, Taylor MRG, Ortega VE, Johnson WC, Gan W, Abecasis G, Nickerson DA, Gupta N, Ardlie K, Woodruff PG, Bowler RP, Meyers DA, Reiner A, Kooperberg C, Ziv E, Vasan RS, Larson MG, Cupples LA, Silverman EK, Rich SS, Heard-Costa N, Tang H, Rotter JI, Smith AV, Levy D, Aguet F, Scott LJ, Raffield LM, Parker SCJ, Abe N, Almasy L, Ament S, Anugu P, Auer P, Avramopoulos D, Balasubramanian A, Barr RG, Barwick L, Beaty T, Becker D, Becker L, Beitelshees A, Benos T, Bezerra M, Bis J, Brody J, Broeckel U, Broome J, Bunting K, Buth E, Carey V, Carty C, Casaburi R, Chaffin M, Chang C, Chang YC, Chavan S, Chen BJ, Chen WM, Choi SH, Chuang LM, Chung RH, Conomos M, Cornell E, Crandall C, Crapo J, Curtis J. Science New York N Y, 2026 Jul 16; 393 (6808): eadx2989Journal ArticleCross-cohort analysis of expression and splicing quantitative trait loci in TOPMed
DOI:10.1126/science.adx2989 PMID: 42462027 -
McAllister N, Zöllner S, Zhang X. bioRxiv, 2026 Jun 29;Journal ArticleScalable ARG-free Detection of Denisovan-mediated Superarchaic Introgression Reveals Heterogeneous Patterns across Populations.
DOI:10.64898/2026.06.25.734355 PMID: PMC13345182 -
Moolhuijsen LME, Zhu J, Mullin BH, Pujol-Gualdo N, Actkins KV, Mack JA, Rao H, Trivedi B, Kentistou KA, Zhao Y, Westergaard D, Tyrmi JS, Thorleifsson G, Zhang Y, Wittemans L, DeVries A, Brewer K, Sisk R, Danning R, Preuss MH, Jones MR, Ruth KS, Andersen M, Azziz R, Banasik K, Boehnke M, Broer L, Brunak S, Chan YM, Chasman DI, Daly M, Ehrmann DA, Fauser BC, Fritsche LG, Hayes MG, He C, Huang H, Kowalska I, Kraft P, Legro RS, Lin N, Loos RJ, Louwers YV, Magi R, McCarthy MI, Morin-Papunen L, Morrison JV, Morton C, Nadkarni GN, Neale BM, Nielsen HS, Nyegaard M, Ostrowski SR, Pedersen OBV, Sørensen E, Mikkelsen C, Erikstrup C, Kaspersen KA, Bruun MT, Aagaard B, Ullum H, Obermayer-Pietsch B, Palotie A, Reeve MP, Salumets A, Saxena R, Spector TD, Stuckey BGA, Thorsteinsdottir U, Uitterlinden AG, Urbanek M, Zöllner S, van Heel DA, Freyman WA, Micheletti SJ, Wilton PR, Wen J, Ashenhurst JR, Poznik GD, Jewett EM, Harney É, German C, Koelsch BL, Guan A, Ambati A, Detweiler SB, Tennen RI, Berns RMK, Wu RR, Abul-Husn NS, Lehman AP, Xu W, Tran V, Aslibekyan S, Saini S, Das S, Bell RK, Su QJ, Kmiecik MJ, McIntyre MH. Nature Genetics, 2026 May 1; 58 (5): 1040 - 1050.Journal ArticleGenomic analyses implicate hormonal and metabolic dysregulation in polycystic ovary syndrome
DOI:10.1038/s41588-026-02543-9 PMID: 42026183 -
da Mota BS, Kumar KH, Reich D, Zöllner S. 2026 Apr 28;PreprintOptimal Reference Panel Design in Ancient DNA Imputation from Coalescent Theory, Simulation, and Real Data Application with an Ancient Reference Panel.
DOI:10.64898/2026.04.27.721163 PMID: 42094450 -
Beck AT, Kang HM, Zöllner S. 2026 Apr 23;PreprintA Benchmark of Modern Statistical Phasing Methods.
DOI:10.1101/2025.06.24.660794 PMID: 42079165 -
Ingold N, Frankcombe S, Bouttle K, Moro E, Canson D, Zöllner S, Patil S, Džigurski J, Glubb DM, Laisk T, O’Mara TA. 2026 Apr 18; medRxiv,PreprintGenetic analysis of female genital tract polyps implicates genome stability, estrogen signalling and shared susceptibility with proliferative gynaecological disorders
DOI:10.64898/2026.04.13.26350740 -
Zhao K, Lam V, Eschenauer G, Vanderwerff B, Zöllner S, Hertz DL, Aitken SL, Pasternak AL. Pharmacogenetics and Genomics, 2026 Feb 2; Publish Ahead of Print:Journal ArticleThe role of uridine diphosphate glucuronosyltransferase 1A4 polymorphisms on posaconazole exposure
DOI:10.1097/FPC.0000000000000594 PMID: 41652826