Francis Paul Worden

 Francis P. Worden
Nancy Wigginton Oncology Research Professor of Thyroid Cancer
Clinical Professor of Internal Medicine, Medical School
Available to mentor
Francis Paul Worden
Francis P. Worden
Clinical Professor
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    • Center Memberships
    • Center Member
      Rogel Cancer Center

    Recent Publications

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    • Journal Article
      MDM2 Inhibition with Alrizomadlin (APG-115) in TP53 wild-type salivary gland cancers: a phase I clinical trial
      Pearson AT, Muzaffar J, Kirtane K, Bellile E, Suresh K, Rosenberg AJ, Worden F, Chung CH, Vokes E, Brenner JC, Bhangale A, McHugh J, Warner K, Nor F, Nor JE, Innes K, Zhai Y, Fu T, Swiecicki PL. Nature Communications, 2026 Dec 1; 17 (1): DOI:10.1038/s41467-026-70653-3
      PMID: 41857036
    • Preprint
      Spatiotemporal Heterogeneity of HPV Integration Architectures Drive Oncogenic Features of Oropharyngeal Cancer.
      Gu W, Bhangale AD, Du X, Deng X, Gensterblum-Miller EU, Currie J, Brummel CV, Nyabashi V, Buchakjian M, Casper KA, Chinn SE, Forner D, Malloy KM, Mierzwa ML, Prince ME, Shah JL, Shuman AG, Stucken CL, Swiecicki PL, Worden FP, Yalamanchi P, McHugh JB, Lang Kuhs KA, Boyle AP, Jiang H, Heft Neal ME, Spector ME, Mills RE, Brenner JC. 2026 Oct 10; DOI:10.64898/2026.10.03.756294
      PMID: 42926491
    • Proceeding / Abstract / Poster
      Twelve-Month Swallowing Outcomes in a Phase II Trial of PET-Adapted Radiation for HPV-Associated Oropharynx Squamous Cell Carcinoma
      Higgins L, Suresh K, Wilkins S, Lyden T, Blakely A, Ambrose M, Elliott DA, Strohbehn G, Prince ME, Casper K, Shuman A, Stucken CL, Forner D, Heft-Neal ME, Yalamanchi P, Brenner C, Swiecicki PL, Worden F, Mierzwa ML, Shah JL. International Journal of Radiation Oncology • Biology • Physics, 2026 Sep 27; 126 (1): e689 - e690. DOI:10.1016/j.ijrobp.2026.06.2147
    • Proceeding / Abstract / Poster
      UMCC 2023.006: A Pilot Phase II Trial of Individualized FDG-PET and DCE-MRI Directed Adaptive RT in HPV-related Stage III Oropharynx Cancer
      Higgins L, Suresh K, Shah JL, Nasser B, Casper K, Prince ME, Forner D, Buchakjian M, Heft-Neal ME, Yalamanchi P, Rosen BS, Shuman A, Stucken CL, Brenner C, D'Silva N, Swiecicki PL, Worden F, Mierzwa ML. International Journal of Radiation Oncology • Biology • Physics, 2026 Sep 27; 126 (1): e689 DOI:10.1016/j.ijrobp.2026.06.2146
    • Journal Article
      Combined Positive Score and Cost-Effectiveness of Perioperative Pembrolizumab for Head and Neck Cancer. Epub ahead of print
      Coyle AH, Hutton DW, Buchakjian MR, Casper KA, Forner DW, Hawley ST, Heft Neal ME, Malloy KM, Mierzwa ML, Prince ME, Shah JL, Sweicicki PL, Shuman AG, Stucken CL, Veenstra CM, Worden FP, Yalamanchi P. JAMA Otolaryngology Head and Neck Surgery, 2026 Sep 1; e262124 - e262124. DOI:10.1001/jamaoto.2026.2124
    • Journal Article
      Systemic Treatment of Thyroid Cancer: ASCO Guideline
      Saba NF, Ismaila N, Adkins D, Agrawal N, Akhave N, Blomain ES, Cabanillas ME, Chen A, Galloway TJ, Harada G, Li D, Noureldine SI, Scharpf J, Sun LL, Tang M, Wirth L, Worden F, Zandberg DP, Beadle BM. Journal of Clinical Oncology, 2026 May 10; 44 (14): 1349 - 1372. DOI:10.1200/JCO-26-00235
      PMID: 41921121
    • Journal Article
      BTCRC HN17-111: A Phase 2 Trial of Androgen Deprivation Therapy (ADT) and Pembrolizumab for Treatment of Advanced-Stage Androgen Receptor (AR)-Positive Salivary Gland Carcinoma
      Bruce JY, Fujioka N, Worden F, Mehra R, Laux D, Chae YK, Sulahadeen A, Pease D, Cao Q, Kimple R, Garcia A, Patel MR. International Journal of Radiation Oncology • Biology • Physics, 2026 Apr 18; 125 (1): e23 DOI:10.1016/j.ijrobp.2026.02.046
    • Journal Article
      Neutrophil to Lymphocyte and Lymphocyte to Monocyte Ratios Predict Improved Survival and Response to Induction Chemotherapy in Locally Advanced Squamous Cell Carcinoma of the Larynx
      Risch Z, Bellile E, Bughrara MS, Swiecicki PL, Casper K, Malloy K, Hogikyan N, Spector M, Shuman A, Stucken C, Chinn S, Chepeha DC, Jolly S, Mierzwa M, Bradford C, Eisbruch A, Carey T, Prince M, Wolf GT, Worden FP. Head and Neck, 2026 May 1; 48 (5): 1311 - 1318. DOI:10.1002/hed.70132
      PMID: 41403153