Assistant Professor of Molecular and Integrative Physiology
Research Assistant Professor
Michigan Neuroscience Institute
Michigan Neuroscience Institute
109 ZINA PITCHER PL, BSRB5053
Ann Arbor, Michigan 48109
crburge@umich.edu
109 ZINA PITCHER PL, BSRB5053
Ann Arbor, Michigan 48109
Available to mentor
Christian R Burgess
Research Assistant Professor
The Burgess lab investigates how learning, as well as changes in motivational and arousal state, impacts how we process the sensory environment. Using neuroanatomical tracing, behavior, optogenetics, and in vivo two-photon calcium imaging in mice, we aim to map the circuits that underlie fundamental behaviors, like sleep and feeding, and elucidate how these circuits impact learning and sensory processing in higher-order brain regions.
Lab website
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Postdoctoral fellowHarvard Medical School, Boston, 2017
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PhDUniversity of Toronto, Toronto, 2012
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BScUniversity of Toronto, Toronto, 2005
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Center MemberCaswell Diabetes Institute
Neuroscience; Sleep; Feeding; Sensory processing; Narcolepsy; Lateral hypothalamus
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Phillips CD, Hodge AT, Myers CC, Leventhal DK, Burgess CR. J Neurosci, 2024 Jun 26; 44 (26):Journal ArticleStriatal Dopamine Contributions to Skilled Motor Learning.
DOI:10.1523/JNEUROSCI.0240-24.2024 PMID: 38806248 -
Iglesias AG, Chiu AS, Wong J, Campus P, Li F, Liu ZN, Bhatti JK, Patel SA, Deisseroth K, Akil H, Burgess CR, Flagel SB. J Neurosci, 2023 Nov 1; 43 (44): 7376 - 7392.Journal ArticleInhibition of Dopamine Neurons Prevents Incentive Value Encoding of a Reward Cue: With Revelations from Deep Phenotyping.
DOI:10.1523/JNEUROSCI.0848-23.2023 PMID: 37709540 -
Toth BA, Chang KS, Fechtali S, Burgess CR. iScience, 2023 Sep 15; 26 (9): 107613Journal ArticleDopamine release in the nucleus accumbens promotes REM sleep and cataplexy.
DOI:10.1016/j.isci.2023.107613 PMID: 37664637 -
Potter LE, Burgess CR. Front Neurosci, 2022 16: 952275Journal ArticleThe melanin-concentrating hormone system as a target for the treatment of sleep disorders.
DOI:10.3389/fnins.2022.952275 PMID: 36177357 -
Burgess CR, Scammell TE. N Engl J Med, 2022 May 19; 386 (20): 1950 - 1952.Journal ArticleCatching Up on REMs.
DOI:10.1056/NEJMcibr2203101 PMID: 35584160 -
McGuire KL, Amsalem O, Sugden AU, Ramesh RN, Fernando J, Burgess CR, Andermann ML. Curr Biol, 2022 Apr 11; 32 (7): 1563 - 1576.e8.Journal ArticleVisual association cortex links cues with conjunctions of reward and locomotor contexts.
DOI:10.1016/j.cub.2022.02.028 PMID: 35245458 -
Ramesh RN, Burgess CR, Sugden AU, Gyetvan M, Andermann ML. Neuron, 2018 Nov 21; 100 (4): 900 - 915.e9.Journal ArticleIntermingled Ensembles in Visual Association Cortex Encode Stimulus Identity or Predicted Outcome.
DOI:10.1016/j.neuron.2018.09.024 PMID: 30318413 -
Garfield AS, Shah BP, Burgess CR, Li MM, Li C, Steger JS, Madara JC, Campbell JN, Kroeger D, Scammell TE, Tannous BA, Myers MG, Andermann ML, Krashes MJ, Lowell BB. Nat Neurosci, 2016 Dec; 19 (12): 1628 - 1635.Journal ArticleDynamic GABAergic afferent modulation of AgRP neurons.
DOI:10.1038/nn.4392 PMID: 27643429
Department News
Revolutionary brain imaging unmasks the intricacies of memory formation.