Scott Barolo, PhD

 Scott Barolo
Director
Program in Biomedical Sciences
Associate Professor of Cell and Developmental Biology
Medical School
[email protected]
Available to mentor
Scott Barolo, PhD
Scott Barolo
Associate Professor
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    • Center Memberships
    • Center Member
      Center for Computational Medicine and Bioinformatics
    • Center Member
      Rogel Cancer Center
    • Center Member
      Center for Cell Plasticity and Organ Design

    Research Overview

    Cells emit molecular signals to "talk" to their neighbors. Those signals are interpreted by special sequences called enhancers in the genomes of the receiving cells, which regulate the expression of nearby genes. How do enhancers respond to signals during development, stem cell function, and disease, and how are those signals translated into precise changes in gene expression.

    Recent Publications

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    • Journal Article
      Developing Future Biologists: developmental biology for undergraduates from underserved communities
      Graniel JV, Teitel J, Glineburg MR, Cohen E, Buttitta LA, Barolo S, Allen BL. Development Cambridge, 2023 Jan 1; 150 (1): DOI:10.1242/dev.201337
      PMID: 36645371
    • Preprint
      Matchathon: A guide to student-faculty connections in PhD programs
      Amemiya H, Lapp Z, Smith C, Durdan M, DiMondo M, Bodiya B, Barolo S. 2020 Nov 9; bioRxiv, DOI:10.1101/2020.11.06.371526
    • Journal Article
      How some men are challenging gender inequity in the lab.
      Powell K. Nature, 2019 Feb; 566 (7745): 567 - 569. DOI:10.1038/d41586-019-00683-z
      PMID: 30814719
    • Journal Article
      Defending harassers harms victims
      Barolo S, Bohr T, Folk J, Libarkin J, McDowell G, McLaughlin BA. Science, 2019 Jan 25; 363 (6425): 355 DOI:10.1126/science.aav7283
      PMID: 30679364
    • Preprint
      Developing Future Biologists: creating and assessing a portable short course to engage underrepresented undergraduate students in developmental biology
      Pinskey JM, Dulka EA, Ramos AI, Echevarría-Andino ML, Lorberbaum DS, Carpenter BS, Martinez-Marquez JY, Budaitis BG, Holloway EM, Raj S, Chin AM, Suarez E, Buttitta LA, Gumucio DL, Wellik DM, Insolera R, Marty-Santos L, Allen BL, Barolo S. 2018 Nov 14; bioRxiv, DOI:10.1101/467092
    • Journal Article
      How to tune an enhancer
      Barolo S. Proceedings of the National Academy of Sciences of the United States of America, 2016 Jun 7; 113 (23): 6330 - 6331. DOI:10.1073/pnas.1606109113
      PMID: 27247414
    • Journal Article
      An ancient yet flexible cis-regulatory architecture allows localized hedgehog tuning by patched/Ptch1
      Lorberbaum DS, Ramos AI, Peterson KA, Carpenter BS, Parker DS, De S, Hillers LE, Blake VM, Nishi Y, McFarlane MR, Chiang ACY, Kassis JA, Allen BL, McMahon AP, Barolo S. Elife, 2016 May 5; 5 (MAY2016): DOI:10.7554/eLife.13550
      PMID: 27146892
    • Journal Article
      Enhancers: Holding out for the right promoter
      Lorberbaum DS, Barolo S. Current Biology, 2015 Jan 1; 25 (7): R290 - R293. DOI:10.1016/j.cub.2015.01.039
      PMID: 25829016