Laurie K Svoboda

 Laurie K Svoboda
John G Searle Assistant Professor of Environmental Health Sciences
Assistant Professor of Environmental Health Sciences
School of Public Health
Assistant Professor of Pharmacology
Medical School
[email protected]
Available to mentor
Laurie K Svoboda
Laurie K Svoboda
Assistant Professor
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    • Center Memberships
    • Center Member
      Frankel Institute for Heart and Brain Health
    • Center Member
      Samuel and Jean Frankel Cardiovascular Center
    • Center Member
      Caswell Diabetes Institute

    Recent Publications

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    • Preprint
      Acute Exposure to Perfluorooctanoic Acid (PFOA) During Cardiomyogenesis disrupts Transcriptional and Electrophysiological Profiles in Differentiated Myocytes
      Ishikawa T, Clark CW, Tapaswi A, Sala-Hamrick KE, Herron TJ, Jimenez-Vazquez EN, Jain A, Jones DK, Colacino J, Monteiro Da Rocha A, Svoboda LK. 2026 May 10; bioRxiv, DOI:10.64898/2026.05.05.723050
    • Preprint
      Exploring the Influence of Chemical Exposures in Breast Cancer Disparities: High-Throughput Transcriptomic Analysis in Normal Breast Cells from Diverse Donors
      Zhao N, Zhao P, Tapaswi A, Polemi K, Thong T, Sexton J, Charles S, Wicha MS, Svoboda L, Zhou X, Colacino JA. 2026 Feb 26; bioRxiv, DOI:10.64898/2026.02.23.707203
    • Journal Article
      Environmentally relevant lead exposure impacts gene expression in SH-SY5Y cells throughout neuronal differentiation
      Morgan RK, Tapaswi A, Polemi KM, Tolrud EC, Bakulski KM, Svoboda LK, Dolinoy DC, Colacino JA. Toxicological Sciences, 2025 Oct 1; 207 (2): 435 - 448. DOI:10.1093/toxsci/kfaf072
      PMID: 40397994
    • Journal Article
      Plasticity of Epigenomic and Transcriptomic Aging Reveals Common Targets for Reprogramming by Environmental Exposures.
      Walker C, Grimm S, Jangid R, Bartolomei M, Dolinoy D, Aylor D, Mutlu G, Biswal S, Zhang B, Hamanaka R, Colacino J, Sartor M, Svoboda L, Wang T, Coarfa C. Res Sq, 2025 Sep 19; DOI:10.21203/rs.3.rs-7368222/v1
      PMID: PMC12458581
    • Journal Article
      Toxicogenomic Insights into Environmental Toxicant Exposures: The TaRGET II Resource.
      Zhang BA, Miao B, Fu S, Coarfa C, Kumar R, Kuntala PK, Park B, Grimm SL, Jangid R, Colacino JA, Svoboda LK, Shao W, Xing X, Li D, Liu S, Hamanaka RB, Lalancette C, Sartor MA, Krapp C, Crawford GE, Patisaul HB, Wiltshire T, TaRGET II Consortium , Aylor D, Biswal S, Mutlu GM, Rajagopalan S, Tang W-Y, Wang T, Dolinoy DC, Bartolomei MS, Walker CL. Res Sq, 2025 Aug 20; DOI:10.21203/rs.3.rs-7285514/v1
      PMID: PMC12393503
    • Journal Article
      Perinatal Exposure to Lead or Diethylhexyl Phthalate in Mice: Sex-Specific Effects on Cardiac DNA Methylation and Gene Expression across Time
      Wang K, Li M, Sartor MA, Colacino JA, Dolinoy DC, Svoboda LK. Environmental Health Perspectives, 2025 Jun 1; 133 (6): DOI:10.1289/EHP15503
      PMID: 40315424
    • Preprint
      Environmentally Relevant Lead Exposure Alters Cell Morphology and Expression of Neural Hallmarks During SH-SY5Y Neuronal Differentiation.
      Morgan RK, Tapaswi A, Polemi KM, Miller JL, Sexton J, Bakulski KM, Svoboda LK, Dolinoy DC, Colacino JA. 2025 Feb 21; DOI:10.1101/2025.02.17.638689
      PMID: 40027621
    • Journal Article
      Sex-stratified piRNA expression analysis reveals shared functional impacts of perinatal lead (Pb) exposure in murine hearts
      Sala-Hamrick KE, Wang K, Perera BPU, Sartor MA, Svoboda LK, Dolinoy DC. Epigenetics, 2025 Jan 1; 20 (1): DOI:10.1080/15592294.2025.2542879
      PMID: 40785069