David O'Dwyer, MD, PhD

 David O Dwyer
Associate Professor of Internal Medicine
Associate Professor of Microbiology and Immunology
Medical School
[email protected]
Available to mentor
David O'Dwyer, MD, PhD
David O Dwyer
Associate Professor
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  • Qualifications
  • Recent Publications

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    • About

    Dr. O’Dwyer is an Associate Professor in the Division of Pulmonary and Critical Care Medicine at the University of Michigan. He graduated from University College Cork Medical School, National University of Ireland in 2004. Dr. O’Dwyer completed his internal medicine residency training through the Royal College of Surgeons of Ireland and was awarded membership of the Royal College of Physicians (RCPI) in 2007. He completed a clinical fellowship in internal medicine and pulmonary medicine at St. Vincents University Hospital and the Royal College of Physicians in 2014. He completed research training in pulmonary medicine graduating with a PhD in pulmonary fibrosis from University College Dublin, National University of Ireland in 2014. He completed clinical fellowship training in pulmonary and critical care medicine at the University of Michigan in 2017.

    Qualifications
    • PhD
      University College Dublin, NUI, National University of Ireland Stillorgan Road, Dublin, Ireland
      2010 - 2014
    • MB BCH BAO
      University College Cork School of Medicine, National University of Ireland (NUI), National University of Ireland Room 2.59, Brookfield Health Sciences Complex, College Road, Cork, Ireland
      1998 - 2004

    Recent Publications

     See All Publications
    • Journal Article
      Toll-like receptor 5 protects against murine lung fibrosis through reduced dysbiosis, and TLR5 deficiency is associated with human IPF
      Sakamachi O, Wiley E, Trempus CS, Jacobs H, Solis A, Johnson CG, Meng X, Hussain S, Roselli A, Lipinski JH, O’dwyer DN, Randall TA, Malphurs J, Papas B, Wu BG, Li Y, Kugler MC, Mehta S, Scappini E, Thomas SY, Li JL, Zhou L, Karmaus PW, Lih FB, Fessler MB, Mcgrath JA, Gibson K, Kass DJ, Gleiberman A, Andrianova E, Walts A, Invernizzi R, Molyneaux PL, Yang IV, Zhang Y, Kaminski N, Segal LN, Schwartz DA, Gudkov AV, Garantziotis S. Science Translational Medicine, 2026 Jun 3; 18 (852): eadw1028 DOI:10.1126/scitranslmed.adw1028
      PMID: 42234773
    • Journal Article
      Abstract 2378 Isolation and Characterization of Novel Streptococcal species from the oral mucosa of a patient with Idiopathic Pulmonary Fibrosis (IPF)
      Klauza S, Pickelner S, Ntamubano S, Falkowski N, Mohan N, Lipinksi J, Oldham J, O'Dwyer D, Kozik A. Journal of Biological Chemistry, 2026 May 22; 302 (5): 112304 DOI:10.1016/j.jbc.2026.112304
    • Journal Article
      Characteristics of severe disease in GL-ILD: a retrospective cohort study
      Bongers KS, Massett A, Patel SV, Konopka KE, Nagaraja V, Wang BR, Kovalszki A, O'Dwyer DN. ERJ Open Research, 2026 Feb 18; 01617 - 02025. DOI:10.1183/23120541.01617-2025
    • Journal Article
      Targeted lung Lactobacillus johnsonii intervention alleviates virus-induced fibrosis post-HCT through PD-L1/PD-1 signaling
      Perkins J, Ravi K, Guo C, Oh G, Garcia Rodriguez B, Jansons S, Sun F, Gurczynski S, Weinberg J, Huffnagle G, O'Dwyer D, Moore B, Zhou X. Science Advances, 2025 Nov 30;
    • Presentation
      IPF contains multitudes: Interrogating the microbiome in IPF
      O'Dwyer D. 2025 Nov 13;
    • Journal Article
      A Quantitative Imaging Measure of Progressive Pulmonary Fibrosis
      Wang JM, Adegunsoye A, Pugashetti JV, Lee CT, Murray S, Mohan N, Nazemi N, Kang E, Chelala L, Kazerooni EA, Flaherty KR, Belloli EA, Sheth JS, O’Dwyer DN, Strek ME, Hatt CR, Han MLK, Chung JH, Oldham JM. American Journal of Respiratory and Critical Care Medicine, 2025 Oct 1; 211 (10): 1785 - 1793. DOI:10.1164/rccm.202501-0208OC
      PMID: 40680162
    • Proceeding / Abstract / Poster
      A CT imaging measure of combined pulmonary fibrosis and emphysema (CPFE)
      Wang J, Pugashetti J, Murray S, Mohan N, Nazemi N, Kang E, Kazerooni E, Flaherty K, Belloli E, Sheth J, O'Dwyer D, Hatt C, Han M, Oldham J. 2025 Dec 1; pa2971 DOI:10.1183/13993003.congress-2025.pa2971
    • Proceeding / Abstract / Poster
      Gut microbiome in idiopathic pulmonary fibrosis
      Kim J, Loe A, Ma S-F, Lipinski J, Ranjan P, Martinez F, Murray S, Noth I, O'Dwyer D. 2025 Dec 1; pa870 DOI:10.1183/13993003.congress-2025.pa870