Kyoung Eun Lee, PhD

 Kyoung E. Lee, PhD
Assistant Professor of Pharmacology
Medical School
University of Michigan Medical School
Pharmacology
1220A MSRB3, 1150 W Medical Center Dr.
Ann Arbor, Michigan 48109
[email protected]
Available to mentor
Kyoung Eun Lee, PhD
Kyoung E. Lee, PhD
Assistant Professor
  • Qualifications
  • Center Memberships
  • Research Overview
  • Links
  • Recent Publications

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    • Qualifications
    • Postdoctoral Fellow
      University of Pennsylvania Perelman School of Medicine, Philadelphia, United States
      2010 - 2018
      Postdoctoral Fellowship
    • PhD
      New York University, New York, New York, United States
      2006 - 2010
    • BS
      Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Korea, Republic Of
      1999 - 2003

    Center Memberships
    • Center Member
      Rogel Cancer Center

    Research Overview

    Role of hypoxia in pancreatic tumorigenesis

    Links
    • Lab Website

    Recent Publications

     See All Publications
    • Journal Article
      Hypoxia Impairs CD8+ T Cell Fitness and Is Associated with a Dysfunctional CD8+ T Cell State in Pancreatic Cancer.
      Mello AM, Pasca di Magliano M, Lee KE. Cancers (Basel), 2026 May 8; 18 (10): DOI:10.3390/cancers18101508
      PMID: 42192869
    • Journal Article
      Hypoxia-Induced Fibroblast IL-6 Promotes Immunosuppressive Macrophage Phenotypes in Pancreatic Cancer.
      Hannifin S, Mello AM, Ngodup T, Kim NH, Pasca di Magliano M, Lee KE. Cells, 2026 Apr 13; 15 (8): DOI:10.3390/cells15080683
      PMID: PMC13114822
    • Journal Article
      A stromal PAI1-tPA axis orchestrates immunosuppression in pancreatic cancer.
      Ngodup T, Elson B, Mello AM, Hannifin S, Liu M, Zhang Y, Shi J, Shah YM, Lawrence DA, di Magliano MP, Lee KE. Sci Adv, 2026 Apr 3; 12 (14): eaea6734 DOI:10.1126/sciadv.aea6734
      PMID: PMC13048251
    • Journal Article
      Long-term low-dose exposure to polystyrene nanoplastics induces morphological and transcriptional reprogramming to enhance metastatic potential of colorectal cancer cells.
      Kim Y, Park SY, Jo A, Ahn S, Kwon J, Jung E-M, Kim H-S, Jeong S, Lee KE, Oh C-K, Kim YH, Oh J-M. Toxicology, 2026 Feb; 520: 154356 DOI:10.1016/j.tox.2025.154356
      PMID: 41290084
    • Journal Article
      Fibroblast STAT3 Activation Drives Organ-Specific Premetastatic Niche Formation.
      Lasse Opsahl EL, Espinoza CE, Olivei AC, Okoye JO, Watkoske H, Hoffman MT, Avritt FR, Elhossiny AM, Bischoff AC, Donahue KL, Poggi M, Kadiyala P, Arya N, Shi J, Lee KE, Zhang Y, Carpenter ES, Szczepanski JM, Frankel TL, Pasca di Magliano M. Cancer Res, 2026 Jan 2; 86 (1): 22 - 39. DOI:10.1158/0008-5472.CAN-25-3472
      PMID: PMC12757723
    • Proceeding / Abstract / Poster
      Hypoxia promotes inflammatory fibroblast formation in pancreatic cancer
      Mello A, Lee KE. 2025 Nov 19;
    • Journal Article
      Paired transcriptional analysis of periodontitis and peri-implantitis within same host: A pilot study.
      Oh J-M, Kim Y, Lee HS, Son H, Heo HJ, Baek SE, Kim EK, Lee J-Y, Lee KE, Kim YH, Kim H-J. J Dent, 2024 Dec; 151: 105366 DOI:10.1016/j.jdent.2024.105366
      PMID: 39357620
    • Journal Article
      Unveiling the Culprit: IL17 Signaling in the Pancreatic Epithelium Drives Tumorigenesis.
      Lee KE, Pasca di Magliano M. Cancer Immunol Res, 2024 Sep 3; 12 (9): 1130 - 1131. DOI:10.1158/2326-6066.CIR-24-0479
      PMID: 38990149