Prabesh Kanel, PhD

 Prabesh Kanel
Research Assistant Professor
Radiology
Medical School
University of Michigan Medical School
Radiology
24 Frank Lloyd Wright Dr, Lobby B, Rm 100
Ann Arbor, Michigan 48105
[email protected]
Available to mentor
Prabesh Kanel, PhD
Prabesh Kanel
Research Assistant Professor
  • About
  • Qualifications
  • Center Memberships
  • Research Overview
  • Recent Publications

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    • About

    I am a research faculty interested in research that uses magnetic resonance imaging (MRI) and positron emission tomography (PET) in studies involving neurodegenerative disorders, with a particular focus on Parkinson's disease and related disorders. I am also keen on exploring the application of machine learning methods to analyze imaging data sets combining different imaging modalities. My global health efforts focus is on improving the lives of people with Parkinsonism worldwide, particularly in low- and middle-income countries, by strengthening diagnosis, treatment, and care, while also driving research and innovation to ultimately prevent and better understand this disorder.

    Qualifications
    • Postdoctoral Research Fellow
      University of Michigan, Radiology, Ann Arbor, United States
      2017 - 2020
      Postdoctoral Fellowship

    Center Memberships
    • Center Member
      Global REACH

    Research Overview

    Machine Learning and its applications in Neuroimaging
    Aging, Parkinson’s disease, Progressive Supranuclear Palsy and related disorders

    Recent Publications

     See All Publications
    • Journal Article
      White matter lesions disrupt cholinergic pathways important for cognition in Parkinson's disease.
      Carli G, Brown T, Michalakis F, Biddix A, Roytman S, Vangel R, Van Hout A, Kanel P, Scott P, Albin RL, Bohnen NI. Brain, 2026 May 12; DOI:10.1093/brain/awag172
      PMID: 42117428
    • Journal Article
      Asymmetric Cholinergic Basal Forebrain Atrophy Marks Freezing of Gait in Parkinson's Disease.
      Craig CE, Kanel P, Ray NJ, Bohnen NI. Eur J Neurosci, 2026 Mar; 63 (6): e70467 DOI:10.1111/ejn.70467
      PMID: PMC13006747
    • Journal Article
      Harmonized Protocol for Subfield Segmentation in the Hippocampal Body on High-Resolution In Vivo MRI From the Hippocampal Subfields Group (HSG)
      Daugherty AM, Carr V, Canada KL, Rådman G, Brown T, Augustinack J, Amunts K, Bakker A, Berron D, Burggren A, Chetelat G, de Flores R, Ding SL, Huang Y, Johnson E, Kanel P, Keresztes A, Kedo O, Kennedy KM, Lee J, Malykhin N, Martinez A, Mueller S, Mulligan E, Ofen N, Palombo D, Pasquini L, Pluta J, Raz N, Riggins T, Rodrigue KM, Saifullah S, Schlichting ML, Stark C, Wang L, Yushkevich P, La Joie R, Wisse L, Olsen R. Hippocampus, 2026 Mar 1; 36 (2): DOI:10.1002/hipo.70073
      PMID: 41635209
    • Preprint
      Cholinergic substrates of gait and postural impairments in Progressive Supranuclear Palsy
      Kanel P, Carli G, Roytman S, Zee SVD, Vangel R, Barr J, Brown T, Spears CC, Narkis A, Slingerland S, Meles S, Laar TV, Scott PJH, Albin RL, Bohnen NI. 2026 Feb 4; Springer Science and Business Media LLC, DOI:10.21203/rs.3.rs-8778777/v1
    • Journal Article
      Baseline Regional Cholinergic Denervation Predicts Cognitive Trajectories in Moderate Parkinson Disease
      Brown T, Carli G, Kanel P, Roytman S, Barr J, Bohnen NI, Albin RL. Annals of Clinical and Translational Neurology, 2026 Jan 1; DOI:10.1002/acn3.70335
    • Journal Article
      Biomarkers.
      Russell JK, Conley AC, Boyd B, Begnoche JP, Schlossberg R, Stranick A, Rosenberg AJ, Acosta LMY, Martin D, Neal Y, Kanel P, Albin RL, Rafii MS, Dumas J, Newhouse PA. Alzheimers Dement, 2025 Dec; 21 Suppl 2: e099363 DOI:10.1002/alz70856_099363
      PMID: 41442139
    • Journal Article
      Retro-Walking and Cholinergic Network Correlates in Parkinson's Disease.
      Griggs A, Carli G, Brown T, Kanel P, Roytman S, Pongmala C, van Emde Boas M, Bohnen NI. J Mov Disord, 2025 Jul 30; DOI:10.14802/jmd.25109
      PMID: 40738499
    • Journal Article
      Differences in cholinergic terminal density in adults with Down syndrome compared to neurotypical controls measured by [18F]-fluoroethoxybenzovesamicol positron emission tomography imaging.
      Russell JK, Conley AC, Boyd BD, Begnoche JP, Schlossberg R, Stranick A, Rosenberg AJ, Acosta LMY, Martin D, Neal Y, Kanel P, Albin RL, Rafii MS, Dumas J, Newhouse PA. Neurobiol Aging, 2025 Apr; 148: 50 - 60. DOI:10.1016/j.neurobiolaging.2025.01.008
      PMID: 39914061