Todd C Hollon, MD

 Todd C. Hollon
Joseph R Novello M.D. Research Professor of Neurosurgery
Alfredo Quinones-Hinojosa M.D. Research Professor of Neurosurgery
Assistant Professor of Neurosurgery
Program Director
Artificial Intelligence in Neurosurgery
Medical School
University of Michigan–Ann Arbor
Department of Neurosurgery
1500 East Medical Center Drive
Ann Arbor, MI 48109-5338
Available to mentor
Todd C Hollon, MD
Todd C. Hollon
Assistant Professor
  • Qualifications
  • Center Memberships
  • Recent Publications

  • Manage Your Profile

    • Qualifications
    • Residency
      University of Michigan–Ann Arbor, Department of Neurosurgery, Ann Arbor, United States
      2013 - 2020
      Residency
    • Residency
      University of Michigan–Ann Arbor, Ann Arbor, United States
      2019 - 2020
      Chief Resident
    • Clinical Fellowship
      University of Utah, Salt Lake City, United States
      2020 - 2020
      Clinical Fellowship
    • Postdoctoral Fellow
      University of Michigan–Ann Arbor, Ann Arbor, United States
      2016 - 2018
      Postdoctoral Fellowship
    • MD
      Ohio State University, Columbus, Ohio, United States
      2009 - 2013
    • BA
      University of Michigan, Ann Arbor, MI, United States
      2004 - 2008

    Center Memberships
    • Center Member
      Rogel Cancer Center
    • Center Member
      Center for Computational Medicine and Bioinformatics
    • Center Member
      AI and Digital Health Innovation
    • Center Member
      Frankel Institute for Heart and Brain Health

    Recent Publications

     See All Publications
    • Journal Article
      Artificial-intelligence-based molecular classification of diffuse gliomas using rapid, label-free optical imaging
      Hollon T, Jiang C, Chowdury A, Nasir-Moin M, Kondepudi A, Aabedi A, Adapa A, Al-Holou W, Heth J, Sagher O, Lowenstein P, Castro M, Wadiura LI, Widhalm G, Neuschmelting V, Reinecke D, von Spreckelsen N, Berger MS, Hervey-Jumper SL, Golfinos JG, Snuderl M, Camelo-Piragua S, Freudiger C, Lee H, Orringer DA. Nature Medicine, 2023 Apr 1; 29 (4): 828 - 832. DOI:10.1038/s41591-023-02252-4
      PMID: 36959422
    • Journal Article
      AI-driven label-free Raman spectromics for intraoperative spinal tumor assessment
      Reinecke D, Müller N, Meissner AK, Fürtjes G, Leyer L, Wang C, Ion-Margineanu A, Maarouf N, Smith A, Hollon TC, Jiang C, Hou X, Al-Shughri A, Körner LI, Widhalm G, Roetzer-Pejrimovsky T, Snuderl M, Camelo-Piragua S, Golfinos JG, Goldbrunner R, Orringer DA, von Spreckelsen N, Neuschmelting V. Npj Digital Medicine, 2026 Dec 1; 9 (1): DOI:10.1038/s41746-025-02279-6
    • Journal Article
      Health system learning enables generalist neuroimaging models.
      Kondepudi A, Rao A, Zhao C, Lyu Y, Harake S, Banerjee S, Ogle J, Joshi R, Meissner A-K, Hou X, Jiang C, Chowdury A, Srinivasan A, Athey B, Gulani V, Pandey A, Lee H, Hollon T. Nat Med, 2026 Jul 10; DOI:10.1038/s41591-026-04497-1
      PMID: 42432292
    • Journal Article
      AI-Powered Pipeline Transforms Neurosurgical Articles Into High-Quality Graphical Abstracts.
      Alyakin A, Stryker J, Lee JV, Feng R, Hollon T, Kondziolka D, Oermann EK. Neurosurg Pract, 2026 Jun; 7 (2): e000230 DOI:10.1227/neuprac.0000000000000230
      PMID: PMC13086415
    • Journal Article
      CNS-Obsidian: A Neurosurgical Vision-Language Model Built From Scientific Publications.
      Alyakin A, Stryker J, Alber DA, Lee JV, Sangwon KL, Duderstadt B, Save A, Kurland D, Frome S, Singh S, Zhang J, Yang E, Park KY, Orillac C, Valliani AA, Neifert S, Liu A, Patel A, Livia C, Lau D, Laufer I, Rozman PA, Hidalgo ET, Riina H, Feng R, Hollon T, Aphinyanaphongs Y, Golfinos JG, Snyder L, Leuthardt EC, Kondziolka D, Oermann EK. Neurosurgery, 2026 May 19; DOI:10.1227/neu.0000000000004070
      PMID: 42153721
    • Preprint
      SIGNAL: A Scalable, Real-World Model for Rapid Intraoperative Molecular Classification of Gliomas Using Stimulated Raman Histology.
      Goff NK, Markert JE, Reinecke D, Springer A, Chen AM, Park M, Malte G, Scotford-Broemmer K, Hoonsbeen S, Eddy K, Chowdury A, Jiang C, Kondepudi A, Meissner A-K, Fürtjes G, Müller N, Neuschmelting V, Pekmezci M, Young J, Freudinger C, Snuderl M, Berger M, Hervey-Jumper S, Golfinos JG, Hollon T, Orringer DA. 2026 May 13; DOI:10.64898/2026.05.11.26350247
      PMID: 42180331
    • Journal Article
      139 General Machine Intelligence for Clinical Neuroimaging
      Hollon TC, Kondepudi A, Lyu Y, Rao A, Zhao C, Chowdury A, Joshi RS, Pandey AS. Neurosurgery, 2026 Mar 17; 72 (Supplement_1): 22 - 23. DOI:10.1227/neu.0000000000003964_139
    • Journal Article
      459 Regional Variability in Gliomagenesis: A Multi-Institutional Spatial Analysis
      Park M, Weiss H, Harake ES, Fang C, Maarouf N, Miller A, Hollon TC, Golfinos JG, Orringer DA. Neurosurgery, 2026 Mar 17; 72 (Supplement_1): 134 - 134. DOI:10.1227/neu.0000000000003964_459

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