Craig J Galban, PhD
Radiology
109 Zina Pitcher Place, A506
Ann Arbor, MI 48109-2200
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About
I am a Professor in the Radiology Department, with affiliated appointments in the Departments of Computational Medicine and Bioinformatics and Biomedical Engineering. I have over 16 years’ experience with medical imaging with an emphasis on quantitative imaging techniques and image processing and analysis for applications in oncology and pulmonology. Since 2011, I have focused my research on the development and analysis of surrogate imaging markers for phenotyping pulmonary diseases. One of my significant contributions to pulmonary imaging is the development of parametric response mapping (PRM), which simultaneously quantifies small airways disease and emphysema in patients with COPD. My groups algorithms, such as PRM, have been integrated into the study design of various US multi-center clinical trials, such as COPDGene and SPIROMICS. In addition, I have patented analytical techniques for improved phenotyping of lung disease, and I have played a critical role in the funding, through my SBIR, and development of a commercial PRM product as an FDA-approved medical imaging device. My group has also made advances in thoracic radiology through the development of a deep learning CNN model for detection and quantification of air trapping on CT scans from school-aged patients with cystic fibrosis
Links
Lab website
Qualifications
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Research FellowNational Institutes of Health, Division of Bioengineering and Physical Science, Bethesda, United States
2005 - 2006
Postdoctoral Research
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Research FellowUniversity Hospital of Essen, Department of Diagnostic and Interventional Radiology, Essen, Germany
2002 - 2005
Postdoctoral Research
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Postdoctoral FellowNational Institutes of Health, National Institute on Aging, Bethesda, United States
1999 - 2002
Postdoctoral Fellowship
Center Memberships
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Center MemberWeil Institute for Critical Care Research
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Center MemberCenter for Computational Medicine and Bioinformatics
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Center MemberRogel Cancer Center
Research Overview
Biomedical Imaging
Functional and Molecular Imaging
Image Analysis
Machine Learning
Computed Tomography
Magnetic Resonance Imaging/Spectroscopy
Recent Publications
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Awadia S, Ziemke EK, Curnutt NM, Kirk E, Thomas J, Zimmerman A, Mileski MJ, Ram S, Abou Zeidane R, Galban C, Woo CM, Speers CW, Leopold J, Rehemtulla A. J Clin Invest, 2026 Jul 28;Journal ArticleTargeting casein kinase 1α-mediated FADD phosphorylation restores sensitivity in select CDK4/6 inhibitor-resistant breast cancer models.
DOI:10.1172/JCI199483 PMID: 42518285 -
Lau BC, Ajaero DP, Hoff BA, Pearson A, Sajjakulnukit P, Wadden J, Adam T, Ji S, Green AL, Nabavizadeh A, Cao Y, Aryal M, Upadhyaya S, Franson A, Galban S, Venneti S, Federowicz B, Shapiro MA, Stuhlmiller TJ, Lyssiotis C, Galban CJ, Parmar HA, Ibrahim M, Koschmann C. Neuro Oncol, 2026 Jul 28;Journal ArticleEarly increase in apparent diffusion coefficient predicts favorable response to Dordaviprone (ONC201) therapy in H3K27M-mutant diffuse midline glioma.
DOI:10.1093/neuonc/noag164 -
Labaki WW, Ram S, Namvar A, Bell AJ, Hoff BA, Kazerooni EA, Galban S, Martinez FJ, Hatt CR, Murray S, Mirkes EM, Gorban AN, Zinovyev A, Han MLK, Galban CJ. Thorax, 2026 Jul 1; 81 (7): 654 - 663.Journal ArticleElastic parametric response mapping: quantitative CT scoring for local COPD severity
DOI:10.1136/thorax-2025-223755 PMID: 41526163 -
Miller S, Polan D, Hadley C, Vineberg K, Lockhart C, O'Dwyer D, Labaki W, Galban C, Allen S, Matuszak M, Jolly S, Suresh K, Matrosic C. Physics and Imaging in Radiation Oncology, 2026 Feb 9;Journal ArticleQuantitative Lung Tissue Functional Analysis for Pulmonary Adverse Event Risk Assessment prior to Thoracic Radiotherapy
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Oyer J, Namvar A, Hoff BA, Bosma C, Labaki WW, Kazerooni EA, Martinez FJ, Hatt CR, Han MK, Galban CJ, Ram S. 2026 Jun 15;PreprintArtificial Intelligence-Based Detection of Airway Mucus Plugs on CT and Associations With Clinical Outcomes in COPDGene.
DOI:10.64898/2026.06.10.26355393 PMID: 42369492 -
Bosma CB, Xu L, Murray S, Paulin LM, Kaufman JD, Hansel NN, Alexis NE, Barr RG, Bon J, Bose S, Comellas AP, Cooper CB, Couper D, Curtis JL, Galban CJ, Hatt CR, Hermann EA, Hoffman EA, Kazerooni EA, Kizhakke Puliyakote AS, Martinez FJ, Ohar JA, Paine R, Putcha N, Raju S, Reinhardt JM, Sack C, Labaki WW, Han MK. Ann Am Thorac Soc, 2026 Jun 2;Journal ArticleAssociation Between Chronic PM2.5 Exposure and CT-Detected Lung Abnormalities in the SPIROMICS Cohort.
DOI:10.1093/annalsats/aaoag143 PMID: 42226013 -
Labaki WW, Hatt CR, Ram S, Galbán CJ, Bose S, Murray S, Meldrum CA, Lagisetty KH, Reddy RM, Kazerooni EA, Han MK. Am J Respir Crit Care Med, 2026 May 27;Journal ArticleEnhancing patient selection for lung volume reduction surgery: a novel quantitative CT approach.
DOI:10.1093/ajrccm/aamag223 -
Ram S, Oyer JM, Ng AS, Labaki WW, Bosma C, Curtis JL, Kazerooni EA, Hatt CR, Paine R, Soni AV, Ritchie AI, Wedzicha JA, Bateman LA, Hoffman EA, Martinez FJ, Galban CJ, Han MK, Investigators SAS. American Journal of Respiratory and Critical Care Medicine, 2026 May 20; 212 (Supplement_1): aamag162.1588Journal ArticleA16-04 Significance of Mucus Plugs in Early COPD: An Analysis of the SOURCE Cohort
DOI:10.1093/ajrccm/aamag162.1588