David Ginsburg

David Ginsburg headshot
James V Neel Distinguished University Professor of Internal Medicine and Human Genetics
Warner-Lambert/Parke-Davis Professor of Medicine
Professor of Internal Medicine
Professor of Human Genetics
Professor of Pediatrics
Medical School and Research Professor
Life Sciences Institute
[email protected]
Available to mentor
David Ginsburg
David Ginsburg headshot
Research Professor
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  • Center Memberships

    • Center Member
      Center for Cell Plasticity and Organ Design
    • Center Member
      Samuel and Jean Frankel Cardiovascular Center
    • Center Member
      Taubman Institute

    Recent Publications

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    • Journal Article
      From Lipoprotein Metabolism to Blood Clotting: Highlights of the 2025 Fredrickson Lipid Research Conference.
      Smith AN, Beg MA, Hur WS, Ginsburg D, Kullo IJ, Davies SS, Tabas I, Williams JW, Mineo C, Cai B, Gupta RK, Amengual J, Schwendeman A, Graf GA, Sorci Thomas M, Zheng Z. J Lipid Res, 2026 Apr 16; 101041 DOI:10.1016/j.jlr.2026.101041
      PMID: 41999980
    • Journal Article
      Deconstructing cardiovascular and coagulation-related traits links dietary ecology to multi-functional snake venom specificity.
      Holding ML, Pontius MHH, Ward MS, Akhtar J, Crowell HL, Svilar D, Keeler KM, Haynes LM, Ginsburg D, Shavit JA. Evolution, 2026 Mar 11; DOI:10.1093/evolut/qpag036
      PMID: 41811938
    • Preprint
      Mapping the Mutational Landscape for Streptokinase Binding to Plasminogen.
      Baid S, Holding ML, Laurin T, Seimeiniak D, Ginsburg D, Haynes LM. 2026 Feb 4; DOI:10.64898/2026.02.04.703780
      PMID: 41684937
    • Journal Article
      Heat shock protein 70s are modifiers of endothelial function in Fabry disease
      Verma R, Cleuren A, Hinkovska-Galcheva V, Decker I, Kelly R, Ginsburg D, Shayman JA. Kidney International, 2026 Jan 1; DOI:10.1016/j.kint.2026.01.004
      PMID: 41579958
    • Journal Article
      Thermodynamics and selection of the plasminogen activator inhibitor-1 latency transition
      Haynes LM, Holding ML, Woodard J, Siemieniak D, Ginsburg D. Journal of Biological Chemistry, 2025 Dec 1; 301 (12): DOI:10.1016/j.jbc.2025.110896
      PMID: 41197721
    • Journal Article
      Phosphatidylserine-rich platelet blebs enhance hemostasis after mucous membrane injury but not after skin or vascular injury: Studies with ANO6-deficient mice
      Novakovic V, Kretz C, Stalker T, Cleuren A, Ginsburg D, Gilbert G. Blood, 2025 Dec 8; 146 (Supplement 1): 4836 DOI:10.1182/blood-2025-4836
    • Journal Article
      Tandem Duplication of Serpin Genes Yields Functional Variation and Snake Venom Inhibitors
      Ward MS, Holding ML, Haynes LM, Margres MJ, Matocq MD, Ginsburg D. Molecular Biology and Evolution, 2025 Nov 1; 42 (11): DOI:10.1093/molbev/msaf290
      PMID: 41218074
    • Journal Article
      Comparative microfluidic and enzymatic analyses reveal multifaceted snake venom resistance and novel VWF behavior in the opossum Monodelphis domestica
      Holding ML, Disharoon D, Haynes LM, Paruchuri BC, Pontius MHH, Golden K, Shavit JA, Desch KC, Ginsburg D, Gupta AS, Cruz Y, Drabeck DH. Plos One, 2025 Sep 1; 20 (9 November): DOI:10.1371/journal.pone.0332686
      PMID: 40971373

    Featured News & Stories

    Department News

    Highlighted Publications: January - May 2026

    Department of Human Genetics faculty are involved in widely diverse areas of research, from Genome Structure and Function research to Evolutionary and Population Genetics.
    Department News

    Highlighted Publications: August - December 2025

    Department of Human Genetics faculty are involved in widely diverse areas of research, from Genome Structure and Function research to Evolutionary and Population Genetics.
    north campus research complex aerial image
    Department News

    Life-changing Therapeutics

    The U.S. Food and Drug Administration recently approved the first available therapeutic treatment for a rare, life-threatening genetic disorder.