Crystal Murray Holmes, DPM, CWSP

 Crystal Holmes
Larry D Soderquist Research Professor
Clinical Professor of Internal Medicine
Medical Director
Podiatry Program
Metabolism
Endocrinology and Diabetes
Clinical Professor of Surgery
Medical School
Office:
University of Michigan
Internal Medicine, Division of Metabolism, Endocrinology and Diabetes
Domino's Farms, 24 Frank Lloyd Wright Dr., Lobby C
Ann Arbor, MI 48106
Available to mentor
Crystal Murray Holmes, DPM, CWSP
Crystal Holmes
Clinical Professor
  • About
  • Links
  • Qualifications
  • Center Memberships
  • Research Overview
  • Recent Publications

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    • About

    Dr. Holmes is a is a dually appointed Clinical Professor of Surgery in the Division of Vascular Surgery and Internal Medicine in the Division of Metabolism, Endocrinology, and Diabetes at the University of Michigan Medical School. After graduating from Kent State College of Podiatric Medicine, Dr. Holmes completed her residency at the University of Texas at San Antonio and joined the University of Michigan in 2006. Dr. Holmes has experience with all aspects of podiatric medicine with special interest in the management of the Diabetic Foot and Wound Care. She is Board Certified with American Board of Podiatric Medicine and is also a Certified Wound Specialist Physician with the American Board of Wound Management.

    Links
    • https://www.uofmhealth.org/profile/1514/crystal-murray-holmes-dpm
    • linkedin
    • https://experts.umich.edu/discover/experts_publication
    • https://pubmed.ncbi.nlm.nih.gov/?term=Holmes%2C crystal

    Qualifications
    • Resident
      University of Texas health Science Center at San Antonio, San Antonio, TX, United States
      2002 - 2005
      Residency
    • DPM
      Kent State University College of Podiatric Medicine, Independence, OH, United States
      1998 - 2002
    • BA, Biology
      Fisk University, Nashville, TN, United States
      1993 - 1997

    Center Memberships
    • Center Member
      Caswell Diabetes Institute

    Research Overview

    Wound care, infection management, diabetic neuropathy, Charcot neuro osteoarthropathy

    Recent Publications

     See All Publications
    • Proceeding / Abstract / Poster
      Sole Searching: Patient Perspectives on Foot Care Delivery for Diabetic Foot Ulcers
      Mizokami-Stout K, Ang L, Hall D, Ramkumar P, Martin C, Noll K, Schmidt B, Holmes C, Pop-Busui R, Schmidt BM. 2026 Sep 28;
    • Journal Article
      Longitudinal Healing and Amputation Trajectories in Diabetic Foot Ulcers: Predictive Power of Wound Area and Duration and Sample-Size Implications from the Diabetic Foot Consortium
      Xu C, Schmidt BM, Krambrink A, Park J, Song P, Jones TLZ, Holmes C, Chen K, Ye W, Kolenic G, Roy S, Sen CK, Busui R, Spino C, Gaynanova I. Wound Repair and Regeneration, 2026 Jul 8;
    • Journal Article
      Wound Healing and Angiogenic Profiling of Dermal Endothelial Cells Isolated From People With Type 2 Diabetes
      Shadiow J, Mazo CE, Varshney P, Kim JJ, Ahn A, Chong SH, Lutz CA, Holmes CM, Munson ME, Schmidt BM, Goonewardena SN, Minshall RD, Solomon TPJ, Ludlow AT, Haus JM. FASEB Journal, 2026 Jun 30; 40 (12): DOI:10.1096/fj.202502874R
      PMID: 42284134
    • Journal Article
      Wound healing and angiogenic profiling of dermal endothelial cells isolated from people with type 2 diabetes
      Shadiow J, Mazo C, Varshney P, Kim J, Ahn A, Holmes C, Munson M, Schmidt BM, Goonewardena S, Minshall R, Solomon T, Ludlow A, Haus J. The FASEB Journal, 2025 Jul 18; 40 (12): DOI:10.1101/2025.07.18.665569
    • Journal Article
      Partnering with Communities to Improve Diabetic Foot Ulcer Care in High-Risk Populations
      Gauvin N, Wayne B, Mathew-Steiner SS, Jones TLZ, Pop-Busui R, Spino C, Maturo F, Schmidt B, Holmes C, Sen CK, Semere W. Advances in Wound Care, 2025 Jun 25; DOI:10.1177/21621918261440435
    • Presentation
      "Diabetic Foot Complications and Management: What the Family Physician Needs to Know"
      2026 Apr 8;
    • Journal Article
      Biomarkers in Diabetic Foot
      Lee H, Brown A, Torrence G, Rothenberg GM, Girgis C, Anwar N, Holmes C, Schmidt B. Clinics in Podiatric Medicine and Surgery, 2025 Dec 12; 43 (2): 195 - 209.
    • Chapter
      Biomarkers in Diabetic Foot
      Lee H, Brown A, Torrence G, Rothenberg GM, Girgis C, Anwar N, Holmes CM, Schmidt BM. 2025 Dec 1; 2: Clinics in Podiatric Medicine and Surgery: Diabetes Updates - What You Need to Know, 195 - 209.

    Featured News & Stories

         On the left, a man in a stretcher poses with a clinical staff member. On the right, a man smiles while standing with three members of his clinical team.
    Health Lab

    Tap dancer’s foot rescued after lifesaving heart surgery

    After undergoing surgery to repair a life threatening aortic dissection, a performer lost his toes during recovery. Now, he's determined to tap dance again.
         feet on hospital bed and clinician looking at them
    Health Lab

    Helping patients with diabetic foot disease

    Diabetes-related foot complications are the most common cause of non-traumatic amputations in the United States. The Michigan Lower Extremity Services clinic at the University of Michigan Health is a multidisciplinary diabetic foot clinic that offers a comprehensive approach to managing diabetic foot disease.