Michael Bachman, MD, PhD

headshot of Michael Bachman
Clinical Professor of Pathology
Clinical Professor of Microbiology and Immunology and Program Director
Clinical Research
Clinical Pathology Division
Medical School
Office:
University of Michigan Medical School
Pathology
1150 W. Medical Center Drive, 7510E MSRB 1
Ann Arbor, MI 48109
Email:
[email protected]
Phone:
Available to mentor
Michael Bachman, MD, PhD
headshot of Michael Bachman
Clinical Professor
  • About
  • Qualifications
  • Center Memberships
  • Research Overview
  • Recent Publications
  • Manage Your Profile

  • About

    Dr. Bachman is a physician scientist studying the Gram-negative bacterial pathogen Klebsiella pneumoniae. He received his MD and PhD degrees from the University of Michigan Medical Scientist Training Program. He then completed a Clinical Pathology Residency and Clinical Microbiology Fellowship at the Hospital of the University of Pennsylvania. He also performed postdoctoral research on the host response to K. pneumoniae iron metabolism in the laboratory of Jeffrey Weiser, MD. He is currently a Medical Director of the Clinical Microbiology Laboratory at Michigan Medicine and a Principal Investigator studying K. pneumoniae pathogenesis and risk factors for infection in hospitalized patients.

    Qualifications

    • MD, PhD
      University of Michigan, 1301 Catherine Road, Ann Arbor, MI, 48109, United States
      1996 - 2004
    • BA
      University of Virginia, Charlottesville, VA, United States
      1992 - 1996

    Center Memberships

    • Center Member
      Frankel Institute for Heart and Brain Health

    Research Overview

    Identification of patient and bacterial genetic risk factors for Klebsiella pneumoniae infections
    Shared and unique fitness factors of Gram-negative bacteria during Bacteremia
    Prediction and prevention of bacterial infections through evaluation of the gut microbiome

    Recent Publications

    See All Publications
    • Journal Article
      Klebsiella pneumoniae factors enhancing bacteremia have distinct contributions to macrophage-mediated, oxidative, and nitrosative stress resistance
      Wilcox AE, Andres CJ, Bachman MA, Holmes CL. Infection and Immunity, 2026 Apr 1; 94 (4): DOI:10.1128/iai.00739-25
      PMID: 41728977
    • Journal Article
      Arginine regulates the mucoid phenotype of hypervirulent Klebsiella pneumoniae
      Ryan BE, Holmes CL, Stark DJ, Shepard GE, Mills EG, Khadka S, Van Tyne D, Bachman MA, Mike LA. Nature Communications, 2025 Dec 1; 16 (1): DOI:10.1038/s41467-025-61047-y
      PMID: 40595687
    • Journal Article
      Patterns of Klebsiella pneumoniae bacteremic dissemination from the lung
      Holmes CL, Dailey KG, Hullahalli K, Wilcox AE, Mason S, Moricz BS, Unverdorben LV, Balazs GI, Waldor MK, Bachman MA. Nature Communications, 2025 Dec 1; 16 (1): DOI:10.1038/s41467-025-56095-3
      PMID: 39824859
    • Preprint
      A Novel Technique to Characterize Klebsiella pneumoniae Populations Indicates that Mono-Colonization is Associated with Risk of Infection.
      Unverdorben LV, Mason S, Wu W, Noda M, Castaneda S, Vornhagen J, Snitkin ES, Rao K, Bachman MA. 2025 Nov 13; DOI:10.1101/2025.11.05.686704
      PMID: 41292861
    • Journal Article
      Integrating genomic and Tn-Seq data to identify common in vivo fitness mechanisms across multiple bacterial species
      Fouts DE, Clarke TH, Severin GB, Brown AN, Ottosen EN, Holmes CL, Moricz BS, Mason S, Sinha R, Anderson MT, DiRita V, Bachman MA, Mobley HLT. Mbio, 2025 Nov 12; 16 (11): 1 - 22. DOI:10.1128/mbio.01988-25
      PMID: 40981419
    • Journal Article
      A Novel Technique to Characterize Klebsiella pneumoniae Populations Indicates that Mono-Colonization is Associated with Risk of Infection.
      Unverdorben LV, Mason S, Wu W, Noda M, Castaneda S, Vornhagen J, Snitkin ES, Rao K, Bachman MA. bioRxiv, 2026 Apr 28;
    • Journal Article
      A Novel Technique to Characterize Klebsiella pneumoniae Populations Indicates that Mono-Colonization is Associated with Risk of Infection.
      Unverdorben LV, Mason S, Wu W, Noda M, Castaneda S, Vornhagen J, Snitkin ES, Rao K, Bachman MA. bioRxiv, 2026 Apr 28;
    • Journal Article
      Infection characteristics among Serratia marcescens capsule lineages
      Anderson MT, Himpsl SD, Kingsley LG, Smith SN, Bachman MA, Mobley HLT. Mbio, 2025 May 1; 16 (5): DOI:10.1128/mbio.00559-25
      PMID: 40237485

    Featured News & Stories

    cells up close from inside lungs in red in the image of a clear see through body
    Health Lab

    Scientists track pneumonia-causing bacteria as they infect the blood stream

    Using an innovative barcoding-style system, a team labels bacteria with short snippets of DNA in mouse models and uses computer analysis to track the movement of K. pneumoniae throughout the body.
    Headshot of Lavinia Unverborden, 2024 Novy Scholarship recipient
    Department News

    M&I Frederick G. Novy Endowed Scholarship goes to Lavinia Unverdorben

    This endowed scholarship was created in 2017 by Lynn Kitabchi, in honor of her grandfather Frederick G. Novy, a world renowned bacteriologist. In 1902, Dr. Novy established the University of Michigan Department of Bacteriology, now the Department of Microbiology and Immunology. The intent for this scholarship is to provide need-based support to Ph.D. students in M&I.