Frank M Davis, MD
1500 E. Medical Center Dr.
Ann Arbor, MI 48109
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Qualifications
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Integrated Vascular Surgery ResidencyUniversity of Michigan, Department of Surgery, Ann Arbor, MI, United States
2016 - 2022
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Integrated Vascular Surgery InternshipUniversity of Michigan, Department of Surgery, Ann Arbor, MI, United States
2015 - 2016
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MDUniversity of Michigan Medical School, Ann Arbor, MI, United States
2010 - 2015
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BS, Cellular and Molecular BiologyUniversity of Michigan, Ann Arbor, MI, United States
2006 - 2010
Center Memberships
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Center MemberSamuel and Jean Frankel Cardiovascular Center
Research Overview
I have a defined clinical and translational interest in the mechanisms underlying aberrant inflammation during aortic aneurysm formation and cardiovascular disease . My long-term goal is to uncover the basic mechanisms responsible for the coordination of immune cells in early tissue repair processes, determine impairments in vascular disease and translate this knowledge to the bedside. Since joining University of Michigan Vascular Surgery, my research has focused on the epigenetic regulation of immune and structural cell pheontypes as it relates to wound healing, aortic aneurysms, and inflammation. This work will provide important information on inflammatory macrophages in peripheral tissue and their contribution to chronic inflammation that may lead to novel treatment modalities.
Recent Publications
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Moon JY, Wolf SJ, Joshi AD, Zhang H, Shadiow J, Bauer TM, Mangum KD, Hughes LD, Audu CO, Melvin WJ, Barrett EC, Rocco S, de Jimenez GS, Estor AL, Nelapudi M, Li Q, Bogle R, Levi B, Davis FM, Obi AT, Moore BB, Tsoi LC, Gudjonsson JE, Gallagher KA. Nature Communications, 2026 Dec 1; 17 (1):Journal ArticleIL-17A is increased in diabetic wounds and impairs keratinocyte function via histone demethylase JMJD3
DOI:10.1038/s41467-025-67456-3 PMID: 41413388 -
Davis FM. 2026 Sep 9;PresentationA Lymphatically Absorbed Kinase Inhibitor to Treat Abdominal Aortic Aneurysm
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He X, Juriga N, Salih S, Callow B, Pierre-Louis D, Joshi A, Bogle R, Tsoi LC, Obi A, Gudjonsson JE, Gallagher K, Davis FM. Circ Res, 2026 Oct 1;Journal ArticleAcetyltransferase MOF Regulates Macrophage Inflammation in Abdominal Aortic Aneurysms.
DOI:10.1161/CIRCRESAHA.126.329212 PMID: 42817883 -
Braet DJ, Carne P, Campello Jorge CA, Delbono L, Eliason J, Figueroa CA, Davis FM, Burris NS. Journal of Vascular Surgery, 2026 Jun 5; 84 (4): 857 - 865.e3.Journal ArticlePreoperative neck growth and size are associated with type 1a endoleak after endovascular aneurysm repair
DOI:10.1016/j.jvs.2026.05.034 PMID: 42235840 -
Davis F. 2026 Sep 9;PresentationOpen and Hybrid Revascularization in the Endovascular Era
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Davis F. 2026 Sep 9;PresentationScientific Session 3
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Davis F. 2026 Sep 9;PresentationScientific Session 3
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Davis F. 2026 Sep 9;PresentationPathological Mechanisms of Abdominal Aortic Aneurysm Development
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