Frank M Davis, MD
1500 E. Medical Center Dr.
Ann Arbor, MI 48109
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Qualifications
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Integrated Vascular Surgery ResidencyUniversity of Michigan, Department of Surgery, Ann Arbor, United States
2016 - 2022
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Integrated Vascular Surgery InternshipUniversity of Michigan, Department of Surgery, Ann Arbor, United States
2015 - 2016
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MDUniversity of Michigan Medical School, Ann Arbor, United States
2010 - 2015
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BS, Cellular and Molecular BiologyUniversity of Michigan, Ann Arbor, United States
2006 - 2010
Center Memberships
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Center MemberSamuel and Jean Frankel Cardiovascular Center
Research Overview
I have a defined clinical and translational interest in the mechanisms underlying aberrant inflammation during aortic aneurysm formation and cardiovascular disease . My long-term goal is to uncover the basic mechanisms responsible for the coordination of immune cells in early tissue repair processes, determine impairments in vascular disease and translate this knowledge to the bedside. Since joining University of Michigan Vascular Surgery, my research has focused on the epigenetic regulation of immune and structural cell pheontypes as it relates to wound healing, aortic aneurysms, and inflammation. This work will provide important information on inflammatory macrophages in peripheral tissue and their contribution to chronic inflammation that may lead to novel treatment modalities.
Recent Publications
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Moon JY, Wolf SJ, Joshi AD, Zhang H, Shadiow J, Bauer TM, Mangum KD, Hughes LD, Audu CO, Melvin WJ, Barrett EC, Rocco S, de Jimenez GS, Estor AL, Nelapudi M, Li Q, Bogle R, Levi B, Davis FM, Obi AT, Moore BB, Tsoi LC, Gudjonsson JE, Gallagher KA. Nature Communications, 2026 Dec 1; 17 (1):Journal ArticleIL-17A is increased in diabetic wounds and impairs keratinocyte function via histone demethylase JMJD3
DOI:10.1038/s41467-025-67456-3 PMID: 41413388 -
Brown CS, Dualeh S, Osborne NH, Albright J, Huang A, Kabbani L, Davis FM, Aronow HD, Kimball AS, Laveroni E, Bove P, Constantinou C, Mouawad NJ, Henke PK. J Vasc Surg, 2026 May 14;Journal ArticleCharacterizing the Association of Heparin Dose and Activated Clotting Time on Lower Extremity Bypass Outcomes.
DOI:10.1016/j.jvs.2026.05.014 PMID: 42140454 -
Davis F. 2026 Jun 3;PresentationAbstract Session III
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Davis F. 2026 Jun 3;Additional ScholarshipAsymptomatic Carotid Artery Stenosis: Clinical Challenges in Vascular Surgery Date of release May 7, 2026 (Number of Listeners: 3,756), Behind the Knife
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Davis F. 2026 Jun 3;Additional ScholarshipAsymptomatic Carotid Artery Stenosis: Clinical Challenges in Vascular Surgery Date of release May 7, 2026 (Number of Listeners: 3,756), Behind the Knife
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Davis F. 2026 Mar 16;PresentationBasic Science: Breast, Plastics and Vascular Oral Session
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Bauer TM, Mangum KD, Buckley SD, Shadiow J, Joshi AD, Audu CO, Moon JY, Hughes LD, Bogel R, Tsoi LC, Li Q, Zhang H, Kunkel S, Gudjonsson JE, Davis FM, Gallagher KA. Jci Insight, 2026 Jan 9; 11 (1):Journal ArticleTNF-α represses fibroblast to myofibroblast transition through the histone methyltransferase Setdb
DOI:10.1172/jci.insight.202699 PMID: 41480743 -
Callow B, He X, Juriga N, Heist K, Jang Y, Pierre-Louis D, Ross B, Davis F. Annals of Vascular Surgery, 2026 Jan 7;Journal Article35. Lp-182 As A Novel Therapeutic Drug For Abdominal Aortic Aneurysms
DOI:10.1016/j.avsg.2025.11.090
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