Janelle Pugashetti, MD

 profile-janelle-pugashetti-2022
Assistant Professor of Internal Medicine
Medical School
Available to mentor
Janelle Pugashetti, MD
profile-janelle-pugashetti-2022
Assistant Professor
  • About
  • Qualifications
  • Center Memberships
  • Recent Publications

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    • About

    Dr. Pugashetti is an Assistant Professor at the University of Michigan, in the Division of Pulmonary and Critical Care. After receiving her undergraduate degree from UCLA, she went on to receive her medical degree, Internal Medicine training, and fellowship in Pulmonary and Critical Care at UC Davis. Dr. Pugashetti has also completed a Master’s Degree in Epidemiology. She joined Michigan Medicine in 2022, where she now provides expert care for patients with interstitial lung disease (ILD) at the Taubman Pulmonary Clinic. She also staffs the Taubman Connective Tissue Disease-Associated ILD Clinic (CTD-ILD) where she works closely alongside Rheumatology colleagues. She leads the Interstitial Lung Disease program at the Ann Arbor VA.

    Dr. Pugashetti is interested in the intersection between autoimmune disease and lung disease. She is an emerging expert in CTD-ILD and is NIH-funded to study predictive biomarkers to guide therapeutic selection, thereby improving outcomes for patients with CTD-ILD.

    Qualifications
    • Fellowship
      University of California Davis, Pulmonary & Critical Care Medicine, Sacramento, United States
      2019 - 2022
    • Residency
      University of California Davis, Internal Medicine, Sacramento, United States
      2019 - 2019
    • M.S., Epidemiology
      University of California Davis, Sacramento, United States
      2021 - 2022
    • M.D.
      University of California Davis, Sacramento, United States
      2012 - 2016
    • B.S., Psychobiology
      University of California, Los Angeles, Los Angeles, CA, United States
      2007 - 2011

    Center Memberships
    • Center Member
      AI and Digital Health Innovation

    Recent Publications

     See All Publications
    • Journal Article
      A15-05 Screening for Interstitial Lung Disease Using Quantitative CT Thresholds
      Wang JM, Pugashetti JV, Murray S, Mohan N, Kang E, Kazerooni E, Flaherty KR, Belloli E, Sheth JS, O’Dwyer DN, Han MK, Hatt CR, Oldham J. American Journal of Respiratory and Critical Care Medicine, 2026 May 20; 212 (Supplement_1): aamag162.2203 DOI:10.1093/ajrccm/aamag162.2203
    • Journal Article
      B23-09 Comparing Survival Outcomes Between Radiomic UIP and Visual UIP Classification in Fibrotic ILD
      Wang JM, Pugashetti JV, Murray S, Mohan N, Kang E, Kazerooni E, Flaherty KR, Belloli E, Sheth JS, O’Dwyer DN, Han MK, Hatt CR, Oldham J. American Journal of Respiratory and Critical Care Medicine, 2026 May 20; 212 (Supplement_1): aamag162.2446 DOI:10.1093/ajrccm/aamag162.2446
    • Journal Article
      B95-01 Prioritizing Therapeutic Targets for Progressive Pulmonary Fibrosis: A Causal Mediation Analysis
      Oldham J, Molyneaux PL, Maddali MV, Newton C, Kim J, Pugashetti JV, Liu GY, Goobie GC, Adegunsoye AO, Ma S, Jenkins RG, Linderholm A, Strek ME, Chen C-H, Fahy W, Zemans RL, Moore BB, Khanna D, Hoffmann-Vold AH, Maher TM, Garcia CK, Wolters PJ, Noth I, Martinez FJ. American Journal of Respiratory and Critical Care Medicine, 2026 May 20; 212 (Supplement_1): aamag162.2615 DOI:10.1093/ajrccm/aamag162.2615
    • Journal Article
      B95-06 Immunosuppressant Exposure and Survival in Interstitial Pneumonia With Autoimmune Features
      Hammoud N, Yu A, Jee AS, Chua F, Hazbeck L, Lee CT, Liu GY, Adams TN, Adegunsoye AO, Wolters PJ, Strek ME, Molyneaux PL, Oldham J, Pugashetti JV, Newton C. American Journal of Respiratory and Critical Care Medicine, 2026 May 20; 212 (Supplement_1): aamag162.2619 DOI:10.1093/ajrccm/aamag162.2619
    • Journal Article
      Sex-related transcriptomic differences in idiopathic pulmonary fibrosis.
      Menon AA, Moll M, Pugashetti JV, Linderholm AL, Liu GY, Krishna R, Noth I, Hunninghake GM, Feghali-Bostwick C, Ghosh AJ. Am J Respir Crit Care Med, 2026 Feb 21; DOI:10.1093/ajrccm/aamag080
      PMID: 41738237
    • Journal Article
      Prioritizing Therapeutic Targets for Interstitial Lung Disease: A Causal Mediation Analysis.
      Oldham J, Molyneaux P, Maddali M, Newton C, Kim J, Konkol S, Pugashetti J, Liu G, Goobie G, Adegunsoye A, Ma S-F, Bornstein D, Murray S, Wain L, Saini G, Stewart I, Johnson S, Jenkins G, Strek M, Linderholm A, Chen C-H, Fahy W, Zemans R, Moore B, Khanna D, Ryerson C, Flaherty K, Suresh M, Hoffmann-Vold A-M, Maher T, Garcia C, Wolters P, Martinez F, Noth I, Smith JA. Res Sq, 2026 Feb 5; DOI:10.21203/rs.3.rs-8714555/v1
      PMID: PMC12889817
    • Journal Article
      Molecular endotypes predict differential response to immunosuppressant therapy in non-IPF interstitial lung disease
      Maddali MV, Pugashetti JV, Pienkos SM, Moore AR, Konkol SB, Kim JS, Ma S-F, Newton CA, Garcia CK, Adegunsoye A, Strek ME, Chen C-H, Linderholm AL, Zemans RL, Moore BB, Wolters PJ, Raj R, Chen JH, Martinez FJ, Noth I, Rogers AJ, Oldham JM. American Journal of Respiratory and Critical Care Medicine, 2026 Feb 1; DOI:10.1093/ajrccm/aamag006
    • Proceeding / Abstract / Poster
      A CT imaging measure of combined pulmonary fibrosis and emphysema (CPFE)
      Wang J, Pugashetti J, Murray S, Mohan N, Nazemi N, Kang E, Kazerooni E, Flaherty K, Belloli E, Sheth J, O'Dwyer D, Hatt C, Han M, Oldham J. 2025 Dec 1; pa2971 DOI:10.1183/13993003.congress-2025.pa2971