Janelle Pugashetti, MD
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About
Dr. Pugashetti is an Assistant Professor at the University of Michigan, in the Division of Pulmonary and Critical Care. After receiving her undergraduate degree from UCLA, she went on to receive her medical degree, Internal Medicine training, and fellowship in Pulmonary and Critical Care at UC Davis. Dr. Pugashetti has also completed a Master’s Degree in Epidemiology. She joined Michigan Medicine in 2022, where she now provides expert care for patients with interstitial lung disease (ILD) at the Taubman Pulmonary Clinic. She leads the pulmonary presence in the Connective Tissue Disease-Associated ILD Clinic (CTD-ILD) program and she directs the Interstitial Lung Disease program at the Ann Arbor VA.
Dr. Pugashetti is interested in the intersection between autoimmune disease and lung disease. She is an emerging expert in CTD-ILD and is NIH-funded to study predictive biomarkers to guide therapeutic selection, thereby improving outcomes for patients with CTD-ILD.
Qualifications
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FellowshipUniversity of California Davis, Pulmonary & Critical Care Medicine, Sacramento, United States
2019 - 2022
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ResidencyUniversity of California Davis, Internal Medicine, Sacramento, United States
2019 - 2019
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M.S., EpidemiologyUniversity of California Davis, Sacramento, United States
2021 - 2022
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M.D.University of California Davis, Sacramento, United States
2012 - 2016
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B.S., PsychobiologyUniversity of California, Los Angeles, Los Angeles, CA, United States
2007 - 2011
Center Memberships
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Center MemberAI and Digital Health Innovation
Recent Publications
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Jee AS, Pugashetti JV, Yazbeck L, Curnow A, Lee CT, Yu A, Hammoud N, Liu GY, Wang JM, Lynn E, Chua F, White E, O'Dwyer DN, Adams T, Wolters PJ, Strek ME, Adegunsoye A, Newton CA, Molyneaux PL, Oldham JM. Eur Respir J, 2026 Oct 23;Journal ArticleFibrotic Morphology and Survival in Interstitial Pneumonia with Autoimmune Features.
DOI:10.1183/13993003.00978-2026 PMID: 42919640 -
Pugashetti JV, Jee AS, Yu AR, Hammoud N, Chua F, Yazbeck L, Lee CT, Liu GY, Adams TN, Adegunsoye A, Wolters PJ, Khanna D, Strek ME, Oldham JM, Molyneaux PL, Newton CA. American Journal of Respiratory and Critical Care Medicine, 2026 Oct 1; 212 (10): 2493 - 2503.Journal ArticleMycophenolate and azathioprine in fibrotic interstitial lung disease
DOI:10.1093/ajrccm/aamag362 PMID: 42432856 -
Menon AA, Moll M, Pugashetti JV, Linderholm AL, Liu GY, Krishna R, Ma SF, Noth I, Hunninghake GM, Feghali-Bostwick C, Ghosh AJ. American Journal of Respiratory and Critical Care Medicine, 2026 Oct 1; 212 (10): 2510 - 2513.Journal ArticleSex-related transcriptomic differences in idiopathic pulmonary fibrosis
DOI:10.1093/ajrccm/aamag080 PMID: 41738237 -
Pugashetti JV, Jee AS, Newton CA. Am J Respir Crit Care Med, 2026 Sep 25;Journal ArticleReply to Gogali and Kostikas: Beyond the Average Treatment Effect: Toward Precision Immunosuppression in Fibrotic Interstitial Lung Disease.
DOI:10.1093/ajrccm/aamag504 PMID: 42788651 -
Zhyvylo I, Sood N, Pugashetti JV, Linderholm AL, Hsu SW, Oldham J, Chen CH, Goncharova EA. Pulmonary Circulation, 2026 Sep 1; 16 (3):Journal ArticleSmoking-Related Clinical and Molecular Abnormalities in Idiopathic Pulmonary Fibrosis—Associated Pulmonary Hypertension
DOI:10.1002/pul2.70349 -
Wang JM, Pugashetti JV, Thompson J, Kang E, Kazerooni EA, Flaherty KR, Belloli EA, Sheth JS, O'Dwyer DN, Han MK, Hatt CR, Oldham JM, Chung JH. Chest, 2026 Aug 12;Journal ArticleSurvival According to Radiomic and Visual Usual Interstitial Pneumonia Classification in Fibrotic Interstitial Lung Disease.
DOI:10.1016/j.chest.2026.08.002 PMID: PMC13494922 -
Adegunsoye A, Oldham JM, Aracena KA, Sickinger D, Ghasemiesfe A, Devaraj A, Pugashetti JV, Lee CT, Udofia I, Ventura IB, Bellam S, Thakrar K, Husain AN, Sperling AI, Noth I, Strek ME, Molyneaux PL, Chelala L, Chung JH. Chest, 2026 Jul 7;Journal ArticleAssociation of Longitudinal Mediastinal Lymph Node Dynamics With Mortality and Fibrosis Progression in Fibrotic Interstitial Lung Disease.
DOI:10.1016/j.chest.2026.05.052 PMID: PMC13639882 -
Pugashetti JV, Jee AS, Yu A, Hammoud N, Chua FJ, Yazbeck L, Lee CT, Liu GY, Adams TN, Adegunsoye AO, Wolters PJ, Strek ME, Oldham J, Molyneaux PL, Newton C. American Journal of Respiratory and Critical Care Medicine, 2026 Jun 24; 212 (Supplement_2): aamag286.168Journal ArticleA75-25 Immunosuppression in Interstitial Lung Disease: A Multi-center Clone-censor-weighting Analysis
DOI:10.1093/ajrccm/aamag286.168