Bruce A Palfey

 labcoat
Associate Professor of Biological Chemistry
Medical School
[email protected]
Available to mentor
Bruce A Palfey
labcoat
Associate Professor
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    • Recent Publications

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    • Journal Article
      Structural and biochemical basis for cannabinoid cyclase activity in marine bacterial flavoenzymes
      Love AC, Sirohi H, Hubert FM, Kao YC, Quinnell DE, Lan T, Gappy R, Sheehy M, Hsu J, Lee A, Zangwill L, Chang T, Palfey BA, Chang G, Moore BS. Nature Chemical Biology, 2026 Jan 1; DOI:10.1038/s41589-026-02257-3
    • Journal Article
      Flavin binding affinity and initial kinetic characterization of DnmZ, a flavin-dependent N-oxygenase
      Vaca V, Huynh K, Hinojosa A, Villanueva Molina D, Palfey B, Vey J. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2022 May 1; 36: DOI:10.1096/fasebj.2022.36.S1.L8016
      PMID: 35556555
    • Journal Article
      An enzymatic activation of formaldehyde for nucleotide methylation
      Bou-Nader C, Stull FW, Pecqueur L, Simon P, Guérineau V, Royant A, Fontecave M, Lombard M, Palfey BA, Hamdane D. Nature Communications, 2021 Dec 1; 12 (1): DOI:10.1038/s41467-021-24756-8
      PMID: 34315871
    • Journal Article
      Fast Kinetics Reveals Rate-Limiting Oxidation and the Role of the Aromatic Cage in the Mechanism of the Nicotine-Degrading Enzyme NicA2
      Tararina MA, Dam KK, Dhingra M, Janda KD, Palfey BA, Allen KN. Biochemistry, 2021 Feb 2; 60 (4): 259 - 273. DOI:10.1021/acs.biochem.0c00855
      PMID: 33464876
    • Journal Article
      Kinetic Analysis of Transient Intermediates in the Mechanism of Prenyl-Flavin-Dependent Ferulic Acid Decarboxylase
      Kaneshiro AK, Koebke KJ, Zhao C, Ferguson KL, Ballou DP, Palfey BA, Ruotolo BT, Marsh ENG. Biochemistry, 2021 Jan 19; 60 (2): 125 - 134. DOI:10.1021/acs.biochem.0c00856
      PMID: 33342208
    • Journal Article
      Tunable Heteroaromatic Sulfones Enhance in-Cell Cysteine Profiling
      Motiwala HF, Kuo YH, Stinger BL, Palfey BA, Martin BR. Journal of the American Chemical Society, 2020 Jan 29; 142 (4): 1801 - 1810. DOI:10.1021/jacs.9b08831
      PMID: 31881155
    • Journal Article
      Erratum: Enzymatic control of dioxygen binding and functionalization of the flavin cofactor (Proceedings of the National Academy of Sciences of the United States of America (2018) 115 (4909-4914) DOI: 10.1073/pnas.1801189115
      Saleem-Batcha R, Stull F, Sanders JN, Moore BS, Palfey BA, Houk KN, Teufel R. Proceedings of the National Academy of Sciences of the United States of America, 2019 Jul 23; 116 (30): 15309 DOI:10.1073/pnas.1910997116
      PMID: 31308229
    • Journal Article
      Structural Basis for Selectivity in Flavin-Dependent Monooxygenase-Catalyzed Oxidative Dearomatization
      Rodríguez Benítez A, Tweedy SE, Baker Dockrey SA, Lukowski AL, Wymore T, Khare D, Brooks CL, Palfey BA, Smith JL, Narayan ARH. ACS Catalysis, 2019 Apr 5; 9 (4): 3633 - 3640. DOI:10.1021/acscatal.8b04575