George A Mashour
Edward F Domino Collegiate Professor of Neuroscience
Vice Dean for Faculty
Professor of Anesthesiology
Program Director, Anesthesiology
Professor of Pharmacology
Medical School
Email:
[email protected]
Available to mentor
George A Mashour
VICE DEAN
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Qualifications
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MD, PhDGeorgetown University, Washington D.C., United States
Research Overview
Multidisciplinary approaches to the study of consciousness
- Network mechanisms of consciousness and unconsciousness
-Theories of consciousness
- Interfaces of sleep neurobiology and general anesthesia
- Intraoperative awareness and metrics of consciousness
Recent Publications
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Huang Z, Tarnal V, Fotiadis P, Vlisides PE, Janke EL, Puglia M, McKinney AM, Jang H, Dai R, Picton P, Mashour GA, Hudetz AG. Scientific Data, 2026 Dec 1; 13 (1):Journal ArticleAn open fMRI resource for studying human brain function and covert consciousness under anesthesia
DOI:10.1038/s41597-025-06442-2 PMID: 41513662 -
Jang H, Fotiadis P, Mashour GA, Hudetz AG, Huang Z. Nature Communications, 2026 Dec 1; 17 (1):Journal ArticleAuthor Correction: Role of thalamus in human conscious perception revealed by low-intensity focused ultrasound neuromodulation (Nature Communications, (2025), 16, 1, (11700), 10.1038/s41467-025-66832-3)
DOI:10.1038/s41467-026-69395-z PMID: 41644954 -
Dai R, Jang H, Hudetz AG, Huang Z, Mashour GA. Cell Rep, 2026 Aug 12; 45 (8): 117830Journal ArticleOpposite network patterns of integration-segregation in psychedelic and sedated states of consciousness.
DOI:10.1016/j.celrep.2026.117830 PMID: 42585017 -
Park Y, Cha Y, Kim H, Kim Y, Woo JH, Lee J, Cho H, Mashour GA, Xu T, Lee UC, Hong SJ, Honey CJ, Moon JY. Current Biology, 2026 Jul 20; 36 (14): 3548 - 3565.e8.Journal ArticleSub-second fluctuations between top-down and bottom-up modes distinguish diverse human brain states
DOI:10.1016/j.cub.2026.06.014 PMID: 42392069 -
Janda AM, Tellor Pennington BR, Colquhoun DA, Kumar SS, Neuman MD, Politi MC, Spino C, Kidwell KM, Swisher L, Bollini M, Vaughn MT, Cloyd C, Pescatore NA, Thelen-Perry S, Gregory SH, du Toit L, Henrichs B, Torres B, Avidan MS, Kheterpal S, Rosen S, Percich J, Valdez M, Karanikolas E, Budelier T, Shoemake R, Patel A, Huynh D, Patel A, Sieg A, Bahamonde A, Santos D, Jung Y, Zittleman A, Coleman R, Dehring M, Sinha A, Romanowski M, Liu X, Balaji M, Shah N, Burns M, Krambrink A, Ignacio RV, Huang S, Swanson B, Hoover D, Moskal D, Menio D, Ziegler G, Klosterman H, Robison L, Campos H, Oberst K, Fodor K, Zukowski L, Grant M, Wurst M, Geml T, Sychtysz M, Hicks M, Dacey R, Kronzer A, McKinnon S, Abdallah AB, Lane-Fall M, Hall BL, Price A, Chu L, Saffary R, Carron J, Vlisides PE, Mashour GA, Kent CD, Hassett A. Anesthesiology, 2026 Jul 1; 145 (1): 59 - 71.Journal ArticleFeasibility Pilot Trial for the Trajectories of Recovery after Intravenous Propofol versus Inhaled Volatile Anesthesia (THRIVE) Pragmatic Randomized Clinical Trial
DOI:10.1097/ALN.0000000000006089 PMID: 41950401 -
Deverett B, Li D, Lii TR, Vlisides PE, Tarnal V, Forsyth A, Sumner R, Sikka P, Schatzberg AF, Muthukumaraswamy S, Mashour GA, Heifets BD. JAMA Psychiatry, 2026 Jun 3; 83 (6): 640 - 644.Journal ArticleGeneral Anesthesia and Discrete Components of Ketamine Neurophysiology
DOI:10.1001/jamapsychiatry.2026.0190 PMID: 41949829 -
Fotiadis P, Jang H, Dai R, Li D, Cofré R, Timmermann C, Mashour GA, Hudetz AG, Huang Z. 2026 Jun 1;PreprintReorganization of Human Brain Waves Across Diverse States of Consciousness.
DOI:10.64898/2026.05.27.728182 PMID: 42282806 -
Douville NJ, Kumar SS, Mashour GA. Anesthesiology, 2026 Apr 1; 144 (4): 1026 - 1027.Journal ArticleMinimum Alveolar Concentration Ratio Factors: Reply
DOI:10.1097/ALN.0000000000005889 PMID: 41619741
Featured News & Stories
Health Lab
Brains and stock markets follow the same rules in crisis, study finds
University of Michigan researchers reveal that the behaviors of brains and economies during crises can be explained using observations common in the realm of physics.
Medical School News
George A. Mashour, M.D., Ph.D., appointed interim executive vice dean for academic affairs/chief academic officer
On Dec. 5, the Board of Regents approved the appointment of George A. Mashour, M.D., Ph.D., as interim executive vice dean for academic affairs (EVDAA) in the Medical School, effective January 1, 2025. He also will serve as interim chief academic officer (CAO) for Michigan Medicine. He takes over EVDAA/CAO duties from Debra F. Weinstein, M.D., who is leaving Michigan Medicine at the end of this year to become president and chief executive officer of the Accreditation Council for Graduate Medical Education
Health Lab
The brain in balance
In a recent study, using network neuroscience, investigators found a way to objectively determine the balance of integration and segregation in fMRI-measured brain signals during wakefulness as well as during sleep and anesthesia.
Department News
Green Anesthesia Initiative exceeds lofty goals for reduction in emissions
The Department of Anesthesiology’s Green Anesthesia Initiative (GAIA) has taken an ambitious approach to environmental sustainability resulting in an 88% reduction of inhaled anesthetic greenhouse gas emissions.
Department News
George Mashour, MD, PhD, featured on the StarTalk Podcast
George Mashour, MD, PhD at the University of Michigan Department of Anesthesiology featured on the StarTalk Podcast.
Department News
Green Anesthesia Initiative quickly shows progress
Is there a common path to the psychedelic experience?
