Matthew Brody, PhD

 Matthew Brody headshot
Pfizer Upjohn Early Career Research Professor of Molecular Pharmacology
Assistant Professor of Pharmacology and Assistant Professor of Internal Medicine
Medical School
[email protected]
Available to mentor
Matthew Brody, PhD
Matthew Brody headshot
Assistant Professor
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    • Center Memberships
    • Center Member
      Samuel and Jean Frankel Cardiovascular Center

    Links
    • Brody Lab Website

    Recent Publications

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    • Journal Article
      Self-cleavage-dependent and -independent functions of Adgrg1/Gpr56 in mice
      Kwarcinski FE, Bernadyn TF, Teuber JP, Nascimento M, Bergin I, Shen T, Gandhi R, Lu X, Brody MJ, Holinstat M, Tall GG. Proceedings of the National Academy of Sciences of the United States of America, 2026 Apr 28; 123 (17): e2527832123 DOI:10.1073/pnas.2527832123
      PMID: 42018412
    • Journal Article
      G protein Gαq subunits engage targets in the nucleus involved in chromatin remodeling and gene expression
      Loomis J, Chandan N, Burroughs M, Abraham S, Zhang R, Cao Y, Brody MJ, Tall GG, Smrcka AV. Journal of Biological Chemistry, 2026 Apr 1; 302 (4): DOI:10.1016/j.jbc.2026.111322
      PMID: 41759731
    • Journal Article
      Cardiomyocyte Rac1 signaling in hypertrophy, arrhythmia, and cardiac stress adaptation
      Teuber JP, Scissors RE, Brody MJ. Journal of Molecular and Cellular Cardiology Plus, 2025 Dec 1; 14: DOI:10.1016/j.jmccpl.2025.100826
    • Journal Article
      Cardiomyocyte Janus kinase 1 (JAK1) signaling is required for cardiac homeostasis and cytokine-dependent activation of STAT3
      Subramani A, Essandoh K, Young MY, Marino FH, Teuber JP, Wagner KU, Brody MJ. Journal of Molecular and Cellular Cardiology, 2025 Aug 19; 207: 13 - 23. DOI:10.1016/j.yjmcc.2025.07.017
    • Presentation
      Session XII: Fusion, Fission, Membrane Contact, and Cell Migration
      2025 Oct 23;
    • Presentation
      Session XII: Fusion, Fission, Membrane Contact, and Cell Migration
      2025 Oct 23;
    • Journal Article
      Rac1 palmitoylation is required for cardiac stress adaptation and regulation of Protein Kinase A signaling.
      Teuber JP, Scissors RE, Subramani A, Madamanchi N, Brody MJ. JCI Insight, 2025 Sep 21; DOI:10.1172/jci.insight.193733
    • Journal Article
      Abstract Wed028: Palmitoylation of Rac1 at Cysteine-178 is Required for Proper Cardiac Stress Adaptation
      Teuber J, Scissors R, Subramani A, Brody M. Circulation Research, 2025 Oct 9; 137 (Suppl_1): DOI:10.1161/res.137.suppl_1.wed028