Yuanfang Guan, PhD
Professor
Email:
[email protected]
Available to mentor
Yuanfang Guan, PhD
Professor
Manage Your Profile
Qualifications
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Ph.D., Molecular BiologyPrinceton University, Princeton, NJ, United States
2005 - 2010
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BS, BiologyThe University of Hong Kong, Hong Kong, China
2002 - 2005
Research Overview
The Guan lab's research focus is machine learning in biology and medical fields.
Links
Guan Lab
Recent Publications
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Huang R, Zhu H, Huang Y, Zhang H, Guan Y, Wang M, Zhang L, Gong Y, Zhao H, Huang S-M, Zineh I, Shen YL, Feng G, Lemery S, Theoret MR, Fashoyin-Aje L, Wang S, Tiwari M, Zou J, Thrun S, Liu Q. npj Digital Medicine, 2026 Oct 14;Journal ArticleDevelopment of a scoring system via an interpretable end-to-end neural network for prognostic stratification of patients with advanced melanoma
DOI:10.1038/s41746-026-03379-7 -
Guan Y. 2026 Jul 8; bioRxiv,PreprintComputationally mapping olfactory receptors to odor percepts using docking energy scores
DOI:10.64898/2026.06.30.735315 -
Deng K, Schwendeman PS, Guan Y. Advanced Science, 2026 May 28; 13 (30):Journal ArticleLearnable Diffusion Framework for Mouse V1 Neural Decoding
DOI:10.1002/advs.202520220 -
Song X, Deng K, Chen M, Guan Y. Science Advances, 2026 Apr 29; 12 (18):Journal ArticlePSGRN: Gene regulatory network inference from single-cell perturbational data through self-training with synthetic gold standards
DOI:10.1126/sciadv.aeb3376 PMID: 42054465 -
Deng K, Wang Y, Min JC, Liu X, Ueharu H, Myers G, Yu L, Hammoud S, Adam A, Saba R, Natogi V, Drysdale C, Chen B, Yee J, Kitzman JO, Lyssiotis CA, Mishina Y, Jones M, Kaartinen V, Guan Y, Khoriaty R, Engel JD, Singh SA. Blood Advances, 2026 Apr 14; 10 (7): 2272 - 2285.Journal ArticleLipid metabolism transcriptomic signature of defective erythropoiesis in Diamond Blackfan anemia syndrome
DOI:10.1182/bloodadvances.2025017318 PMID: 41576344 -
Huang R, Zhu H, Huang Y, Zhang H, Guan Y, Wang M, Zhang L, Gong Y, Zhao H, Huang S-M, Zineh I, Shen YL, Feng G, Lemery S, Theoret MR, Fashoyin-Aje L, Wang S, Tiwari M, Zou J, Thrun S, Liu Q. 2025 Dec 20; Research Square,PreprintDevelopment of A Scoring System via An Interpretable End-to-end Neural Network for Prognostic Stratification of Patients with Advanced Melanoma
DOI:10.21203/rs.3.rs-8118762/v1 -
Deng K, Xu X, Zhou M, Li H, Keller ET, Shelley G, Lu A, Garmire L, Guan Y. Nature Communications, 2025 Dec 1; 16 (1):Journal ArticleImageDoubler: image-based doublet identification in single-cell sequencing
DOI:10.1038/s41467-024-55434-0 PMID: 39747095 -
Schreiber JM, Boix CA, wook Lee J, Li H, Guan Y, Chang CC, Chang JC, Hawkins-Hooker A, Schölkopf B, Schweikert G, Carulla MR, Canakoglu A, Guzzo F, Nanni L, Masseroli M, Carman MJ, Pinoli P, Hong C, Yip KY, Spence JP, Batra SS, Song YS, Mahony S, Zhang Z, Tan W, Shen Y, Sun Y, Shi M, Adrian J, Sandstrom RS, Farrell NP, Halow JM, Lee K, Jiang L, Yang X, Epstein CB, Strattan JS, Bernstein BE, Snyder MP, Kellis M, Noble WS, Kundaje AB. Genome Biology, 2025 Dec 1; 26 (1):Journal ArticlePublisher Correction: The ENCODE Imputation Challenge: a critical assessment of methods for cross-cell type imputation of epigenomic profiles (Genome Biology, (2023), 24, 1, (79), 10.1186/s13059-023-02915-y)
DOI:10.1186/s13059-025-03494-w PMID: 39948633
Featured News & Stories
Department News
Five DCMB faculty are promoted, congratulations!
Five DCMB faculty were promoted. They are Yuanfang Guan, Ph.D., Jie Liu, Ph.D., Ryan Mills, Ph.D., Stephen C.J. Parker, Ph.D., and Arvind Rao, Ph.D. Congratulations!
