Michigan Alzheimer’s Disease Research Center at AAIC 2025
Welcome to our showcase of contributions from the Michigan Alzheimer’s Disease Research Center (Michigan ADRC) at the Alzheimer’s Association International Conference (AAIC) 2025. We are proud to highlight the impactful work our faculty, staff, trainees, and collaborators are presenting at this year’s conference in Toronto.
Each year, AAIC gathers researchers, clinicians, and advocates from around the world to advance the science of Alzheimer’s disease and related dementias. The Michigan ADRC community is honored to take part in this global dialogue, sharing discoveries, fostering collaboration, and continuing our mission to improve lives through research and innovation.
From breakthroughs in early detection and biomarker research to studies focused on caregiving, equity, and prevention, these sessions reflect the depth and diversity of work happening across our Center. You can find a full list of Michigan ADRC-led posters and talks at AAIC 2025, including topics, presentation times, and locations, by viewing the list below.
If you are attending AAIC 2025 in person, we invite you to stop by these sessions, connect with our team, and learn more about our work. And whether you're joining in Toronto or following from afar, thank you for supporting the Michigan ADRC research community—we’re grateful to share this journey with you.
We look forward to connecting with you at AAIC 2025!
| Date | Time | Location | Poster Title | Authors | Poster Number | Presenter |
| Sunday, July 27 | ||||||
| 7:30 am - 4:15 pm | Exhibit | Balancing Act: Exploring Well-Being in Sandwiched and Non-Sandwiched Caregivers | Virginia Gallagher, PhD, Natasha L Nemmers, PhD, Yuchen Zhang, and Sarah E. Patterson | #97629 | Virginia Gallagher and Natasha Nemmers | |
| 7:30 am - 4:15 pm | Exhibit | Environmentally Relevant Perinatal Lead Exposure Alters Metabolic Pathways Related to Oxidative Stress, Inflammation, and Lipid Metabolism in Mouse Cerebral Cortex and Blood Plasma with Implications for Dementia | Rachel K Morgan, Evelyn K Matei, Tomoko Ishikawa, Junru Pan, Katelyn M Polemi, Dana C Dolinoy, Kelly M. Bakulski and Justin A Colacino | #102954 | Rachel Morgan | |
| 7:30 AM – 4:15 PM | Exhibit | Rethinking the Obesity Paradox: BMI and Longitudinal Cognitive Decline in Older Adults | Subhamoy Pal, PhD, Bilal Irfan, MS, Jonathan Reader, MS, Kelly Bakulski, PhD, Voyko Kavcic, PhD; Bruno Giordani, PhD | #108137 | Subhamoy Pal | |
| 7:30 AM – 4:15 PM | Exhibit | Living Arrangements and Dementia Care Networks: Variations in Size, Composition, and Care Tasks | Natasha Nemmers, PhD, Wenjing Li, MS, Wenhua Lai, PhD, Amanda Leggett, PhD | #97451 | Natasha Nemmers | |
| 7:30 AM – 4:15 PM | Exhibit | Balancing Acts: Exploring Well-Being in Sandwiched and Non-Sandwiched Caregivers | Virginia Gallagher, PhD, Natasha Nemmers, PhD, Yuchen Zhang, BSN, Sarah Patterson, PhD | #97629 | Virginia Gallagher | |
| 7:30 AM – 4:15 PM | Exhibit | Preliminary and Ongoing Investigation of Human Induced Pluripotent Stem Cell-Derived Frontotemporal Dementia Cortical Organoids Assessed by Mass Spectrometry | Merci N Best, PhD, Jared Lamp, PhD, Andrew Umstead, MPS, Mariana Sierra, BS, Amber Spencer, BS, Ilkim Erturk, DVM, Elizabeth M Tank, PhD, Jonathan Sexton, PhD, Sami Barmada, MD, PhD, Irving E Vega, PhD, and Henry L Paulson, MD, PhD | #102339 | Merci Best | |
| 7:30 AM – 4:15 PM | Exhibit | Residential proximity to a lead releasing facility is associated with cognition in KHANDLE and STAR cohort | Scarlet Cockell, Kelly Bakulski, Ai-Lin Tsai, Chinomnso Okorie, Stacey Alexeeff, Rachel Whitmer, Paola Gilsanz, Kathryn Conlon | #103527 | Scarlet Cockell | |
| 7:30 AM – 4:15 PM | Exhibit | Predictors of Alzheimer’s Disease Treatment Optimism Among a Nationally Representative Sample of Older Adults | Sarah McCain, MPH, Jonathan M. Reader, MS, and J. Scott Roberts, PhD | #107068 | Sarah McCain | |
| 7:30 AM – 4:15 PM | Exhibit | Community support utilization by Black dementia caregivers: key factors | Florence Johnson, Sheria Robinson-Lane, Marie Jeanne Tuyisenge, Jada Jackson, Tasneem Qurashi, Priya Tripathi, and Bruno Gordani | #104384 | Florence Johnson | |
| 7:30 AM – 4:15 PM | Exhibit | Rethinking the Obesity Paradox: BMI and Longitudinal Cognitive Decline in Older Adults | Subhamoy Pal, PhD; Bilal Irfan, MS, Jonathan Reader, MS; Kelly Bakulski, PhD; Voyko Kavcic, PhD; Bruno Giordani, PhD | #108137 | Subhamoy Pal | |
| Monday, July 28 | ||||||
| 7:30 AM – 4:15 PM | Exhibit | Neuropsychiatric Symptoms, Gray Matter Microstructural Integrity and Alzheimer’s Disease Pathology in Older Adults with Amnestic Mild Cognitive Impairment and Dementia of Alzheimer’s Type | Quentin Devignes, Patrick J. Pruitt, Kenneth Petscavage, Robert A. Koeppe, Roger L. Albin, Scott Peltier, Annalise Rahman-Filipiak, Bruno Giordani, Benjamin M. Hampstead, Alexandru D. Iordan | #105226 | Quentin Devignes | |
| 7:30 AM – 4:15 PM | Exhibit | Health-Related Behaviours in Octogenarians and Nonagenarians with Robust Cognitive Longevity: Progress from the SuperAging Research Initiative | Roberts, Angela & Ooteghem, Karen & McIlroy, Bill & Culum, Ivan & Beyer, Kit & Thai, Vanessa & Aulakh, Nimrit & Li, John & Dunne, Ciara & Lim, Andrew & Swartz, Richard & Finger, Elizabeth & Cook, Amanda & Okonkwo, Ozioma & Goldstein, Felicia & Huentelman, Matthew & Geula, Changiz & Rogalski, Emily | #105769 | ||
| 7:30 AM – 4:15 PM | Exhibit | Increased Cdkn2a, a regulator of cellular senescence, in the PS19 mouse model of tauopathy. | Dylan Finneran, Brianna G Jackman, Taylor Desjarlais, Dave Morgan, & Marcia N Gordon | #107206 | Dylan Finneran | |
| 7:30 AM – 4:15 PM | Exhibit | Wild type human tau is more prone to phosphorylation than P301L-tau in the presence of amyloidosis in mouse brain. | Dave Morgan, Dylan Finneran, Brianna G Jackman, Taylor Desjarlais, & Marcia N Gordon. | #3107183 | Dave Morgan | |
| 7:30 AM – 4:15 PM | Exhibit | Predictors of transitions between normal cognition, cognitive impairment, and dementia in a longitudinal cohort | Nan Shi, MPH, Kelly M. Bakulski, PhD, James Burke, MD, MS and Andrew F Brouwer, PhD, | #97437 | Andrew Brouwer | |
| 7:30 AM – 4:15 PM | Exhibit | DNA methylation age acceleration and cognitive status among older adults in the US, 1999-2002 | Erika Walker, MPH, Scarlet M Cockell, MPH, Belinda L Needham, PhD, Sung Kyun Park, ScD, MPH and Kelly M Bakulski, PhD | #100927 | Erika Walker | |
| 7:30 AM – 4:15 PM | Exhibit | DNA methylation-wide association study of prevalent and incident dementia in the US Health and Retirement Study | John Dou, Scarlet M Cockell, Herong Wang, Lindsay H Ryan, Matthew Zawistowski, Erin B Ware, and Kelly M. Bakulsk | John Dou | ||
| 7:30 AM – 4:15 PM | Exhibit | Comparing the straightness of driving between senior drivers with elevated amyloid burden and those without | Anu M. Kumar, Yi Lu Murphey, Amanda Cook Maher, Carol Persad, Robert Koeppe, & Bruno Giordani | #103449 | ||
| 7:30 AM – 4:15 PM | Exhibit | Change in post-task resting state EEG differences between cognitively normal adults with and without elevated PET Amyloid | Amanda Cook Maher, PhD, Jordan R Bross, BA, Carol C Persad, PhD, McKenna Sawitz-Warren, BA, Bruno Giordani, PhD, and Voyko Kavcic, PhD | #107930 | Amanda Maher | |
| 7:30 AM – 4:15 PM | Exhibit | Exploring variability in daily health-related behaviors as a feature of exceptional cognitive aging in people 80+ years of age: Early findings from the SuperAging Research Initiative | #108450 | |||
| Tuesday, July 29 | ||||||
| 7:30 AM – 4:15 PM | Exhibit | Improved Detection of Mild Cognitive Impairment from Temporal Language Markers Using Subject-invariant Representation Learning using I-CONECT data | Bao Hoang, Yijiang Pang, Siqi Liang, Hiroko H Dodge, and Jiayu Zhou | #103800 and #110588 | Jiayu Zhou | |
| 7:30 AM – 4:15 PM | Exhibit | Exploring racial and diagnostic differences in motor performance along the Alzheimer’s disease continuum: Insights from the ARMADA study | Kylie R. Kadey, PhD, Subhamoy Pal, PhD, Bruno Giordani, PhD, Aubryn H Samaroo, BS, Emily H Ho, PhD, Richard C. Gershon, PhD, Sandra Weintraub, PhD, Vitali Ustsinovich, MA, and Amanda Cook Maher, PhD | #102194 | ||
| 7:30 AM – 4:15 PM | Exhibit | Early Detection of MCI based on both EEG and NIH-Toolbox Cognition Scores | Ming Gu, Boxin Sun, Voyko Kavcic, Jian Ren, Bruno Giordani, Tongtong Li | #104092 | Tongtong Li | |
| 7:30 AM – 4:15 PM | Exhibit | Linear regression analysis of driving straightness among older adult drivers with and without elevated amyloid burden | Anu M. Kumar, Yi Lu Murphey, Amanda Cook Maher, Carol Persad, Savannah Rose, Robert Koeppe, & Bruno Giordani | #103521 | ||
| 7:30 AM – 4:15 PM | Exhibit | Prediction of Amyloid Status using EEG-Based Brain Effective Connectivity | Boxin Sun, Ming Gu, Amanda Maher, Kelly N. DuBois, Nicholas M. Kanaan, Jordan Bross, Robert Koeppe, Voyko Kavcic, Jian Ren, Tongtong Li, and Bruno Giordani | #104038 | ||
| 7:30 AM – 4:15 PM | Exhibit | Determinants of Dementia Diagnosis in U.S. Primary Care in the Past Decade: A Scoping Review | Chelsea G. Cox, MPH, MSW, Barbara L. Brush, PhD, ANP-BC, FAAN, Lindsay C. Kobayashi, PhD and J. Scott Roberts, PhD | #98209 | Chelsea Cox | |
| Wednesday, July 30 | ||||||
| 7:30 AM – 4:15 PM | Exhibit | Enrollment and Scientific Update for the Multisite SuperAging Research Initiative | Amanda Cook Maher, PhD, Robert Bartha, PhD, Ivan Culum, PhD, Elizabeth Finger, MD, Changiz Geula, PhD, Felicia C. Goldstein, PhD, Matthew J Huentelman, PhD, Andrew Lim, MD, Adam Martersteck, PhD, Marsel Mesulam, MD, Ozioma C Okonkwo, PhD, Henry L Paulson, MD, PhD, Angela C Roberts, PhD, MA-SLP, Edna Rose, PhD, MSW, RN-BC, Phyllis Timpo, MS, Antoine R Trammell, MD, MPH, Richard H Swartz, MD, PhD, Karen Van Ooteghem, PhD, Emily J Rogalski, PhD, and SuperAging Research Initiative | #104075 | Amanda Maher | |
| 7:30 AM – 4:15 PM | Exhibit | Solo Act or Teamwork: Contrasting Characteristics of Caregiving Networks by Dementia Status and Single Caregiver Structures | Amanda Leggett, PhD, Shushun Ren, M.S, Sophia Tsuker, B.S.,Wenhua Lai, PhD, Natasha Nemmers, PhD | #97452 | Amanda Leggett | |
| 7:30 AM – 4:15 PM | Exhibit | Caregiving Preparedness and Self-Efficacy Following Alzheimer’s Disease Biomarker Disclosure: Findings from Care Partners of Individuals with Cognitive Impairment | Sara J. Feldman, Mary Lesniak, Gloria Whitaker, Haley Kohl, Keiris Surita, J. Scott Roberts, Benjamin M. Hampstead, & Annalise Rahman-Filipiak | #104881 | Sara Feldman | |
| 7:30 AM – 4:15 PM | Exhibit | A personalized multi-platform assessment of somatic mosaicism in the human frontal cortex | Weichen Zhou, PhD, Camille Mumm, Yanming Gan, Jessica A Switzenberg, PhD, Jinhao Wang, Paulo De Oliveira, PhD, Kunal Kathuria, PhD, Steven J Losh, Torrin L McDonald, PhD, Brandt Bessell, Kinsey Van Deynze, Michael J McConnell, PhD, Alan P Boyle, PhD and Ryan E Mills, PhD | #103962 | Weichen Zhou | |
| 7:30 AM – 4:15 PM | Exhibit | The Perceptions of Foreign-Born Arab Americans on Dementia and Mental Health Research: A Focus Group Study | Sumiyyah M Zimami, PhD Candidate, MSN, RN, Hala J Darwish, PhD, APN, RN, FAAN, Kristine J Ajrouch, PhD, Sarah Abboud, PhD, RN and Daniel Velez Ortiz, PhD, | #107203 | Sumiyyah Zimami | |
| 7:30 AM – 4:15 PM | Exhibit | Bilingualism as a Unique Resource for Cognitive Aging | Kristine J. Ajrouch, Toni C. Antonucci, Simon Brauer, Wassim Tarraf, Laura B. Zahodne | #105106 | Kristine Ajrouch | |
| Virtual | ||||||
| Online | Exploring driving behaviors as biomarkers for early identification of individuals at risk for Alzheimer's Disease | Sai Santosh Reddy Danda, Yi Lu Murphey, Amanda Cook Maher, Savannah Rose, Carol Persad, Robert Koeppe, & Bruno Giordani | #103413 | |||
| Online | Trip-Based Measures of Naturalistic Driving: Exploring connections to older adult drivers with respect to amyloid-positive and amyloid-negative | Alper Kursat Uysal, Sai Shanmukh Varma Rudraraju, Sai Santosh Reddy Danda, Yi Lu Murphey, Amanda Cook Maher, Carol Persad, Savannah Rose, Robert Koeppe, & Bruno Giordani | #103469 | |||
| Online | Glucose lowering treatment in high fat diet-induced cognitive impairment indicates that cognitive deficits may be glucose independent | Sarah E. Elzinga, Kai Guo, Ali Turfah, Rosemary E. Henn, Ian F. Webber-Davis, John M. Hayes, Crystal M. Pacut, Samuel J. Teener, Andrew D. Carter, Diana M. Rigan, Adam M. Allouch, Dae-Gyu Jang, Rachel Parent, Emily Glass, Geoffrey G. Murphy, Stephen I. Lentz, Kevin S. Chen, Lili Zhao, Junguk Hur, Eva L. Feldman | #98593 | Sarah Elzinga | ||
| Online | Daily affect within care dyads: links to cortisol and alpha-amylase synchrony in couples living with early-stage dementia. | Polenick CA, Turkleson A, Garner C, Liu Y, Birditt KS | Courtney Polenick | |||
| Online | RAVLT Delayed Recall predicts two-year changes in cerebrospinal fluid total-tau for cognitively healthy older adults | John L. Woodard, PhD, J. Carson Smith, PhD, Kristy A. Nielson, PhD, Sally Durgerian, S.B., Audrey Zhu, MS, Maria Khrestian, MS and Stephen M. Rao, PhD | Lauren Sather | |||
| Online | Delayed recall predicts change in cerebrospinal fluid biomarkers over two years. | Dixon, B.J., Woodard, J.L., Bekris, L.M., Khrestian, M., DiFilippo, F.P., Nielson, K.A., Smith, J.C., Durgerian, S. & Rao, S.M. | #106534 | Bradley J. Dixon | ||
| Online | The Impact of Returning Individual Research Results: Program Evaluation of the Michigan Alzheimer’s Disease Research Center’s Participant Feedback Program | Flores, B., Kohl, H., Maher, A., Posby, B., Gierzynski, T., Whitaker, G., Pleskaczynska, J., Reader, J., Cooper, M., Hampstead, B. M., Roberts, J. S., & Rahman-Filipiak, A | #108817 | Bernardo Flores | ||
| Online | Assessing Motivation for Engaging in an Alzheimer's Disease Research Registry Purpose: To better understand why respondents chose to join the registry, and whether motivations differ by demographic characteristics of the participant. | Le'Elle Davis, MS, Reginald Wilburn, BS, Theresa F. Gierzynski, MSW, Jennifer Dinh, Kate Hanson, MA, Holly Bunker, MA, Bernardo Flores, BS, Joshua T Fox-Fuller, PhD, Renee Gadwa, MBA, Arijit K Bhaumik, BA, CCRP, J. Scott Roberts, PhD, Henry L Paulson, MD, PhD, and Annalise Rahman-Filipiak, PhD | #99720 | Le’Elle Davis | ||
| Online | Evaluating Factors that Increase ‘Matriculation’ from a Research Registry to ADRD Research Studies | Reginald Wilburn, BS, Le'Elle Davis, MS, Theresa F. Gierzynski, MSW, Jennifer Dinh, Kate Hanson, MA, Holly Bunker, MA, Bernardo Flores, BS, Joshua T Fox-Fuller, PhD, Renee Gadwa, MBA, Arijit K Bhaumik, BA, CCRP, J. Scott Roberts, PhD, Henry L Paulson, MD, PhD, and Annalise Rahman-Filipiak, PhD | #101108 | Reginald Wilburn | ||
| Presentations | ||||||
| Sunday, July 27, 2025, from 8:00 AM – 8:45 AM EDT | Room 106 | Exploring Emotional Well-Being in Exceptional Aging: Data from the SuperAging Research Initiative | Claire Alexander, PhD, Kylie Kadey, PhD, Rhiana Schafer, BA, Ozioma C. Okonkwo, PhD, Felicia Goldstein, PhD, Angela C Roberts, PhD, Adam Martersteck, PhD, The SuperAging Research Initiative, Amanda Cook Maher, PhD, Emily Rogalski, PhD | |||
| Wednesday, July 30, 2025, from 2:00–3:30 PM EDT | Room 801 | Association of Neighborhood-Level Disadvantage with Antemortem MRI Brain Volumes in a Multi-site Brain Bank Donor Cohort | Hammond A, Navaratna R, Moody J, DeWitt A, Alosco ML, Atri A, Bakulski KM, Beach TG, Brewer JB, Carrion C, Chodosh J, Fabio A, Tomaszewski Farias S, Henderson VW, Kofler J, Langbaum J, Lepping RJ, Mahnken JD, Marsh K, Meyer OL, Morris JK, Neugroschl JA, O'Connor MK, Paulson HL, Reiman EM, Rodriguez Espinoza P, Sano M, Saykin AJ, Shaaban E, Sultzer DL, Whitmer RA, Wisniewski T, Zhu CW, Buckingham WR, Powell WR, Kind AJH, Betthauser T, Bendlin BB. | Angel Hammond |
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