Anna Megdell

Science writer and editor

Megdell joined the University of Michigan Rogel Cancer Center communications team in 2022. Prior to that she served as the natural sciences writer for the University of Michigan College of Literature, Science, and the Arts. Contact: [email protected]

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Health Lab

Researchers identify novel biomarker linked to renal cancer recurrence

Researchers from the University of Michigan Health Rogel Cancer Center have discovered a biomarker that could help identify which renal cancer patients have a higher risk of recurrence.
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Health Lab

Pediatric brain tumors rely on different metabolic “route” to fuel treatment resistance

Researchers at the University of Michigan Health Rogel Cancer Center are one step closer to understanding how pediatric DIPG tumors work.
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Health Lab

White blood cell “nets” could be early warning sign of major immunotherapy complication

When white blood cells, meant to protect the body from infection, are overly activated, they eject their DNA into nets, further disrupting the immune system and making patients more likely to develop a potentially severe reaction to immunotherapy.
[from left to right] Filip Bednar, M.D., Ph.D.; Marina Pasca di Magliano, Ph.D.; Timothy Frankel, M.D.
Illuminate

Collaborative Excellence

Marina Pasca di Magliano, Maud T. Lane Professor of Surgical Immunology, discusses the collaboration that makes Rogel’s pancreatic cancer team unique.
Close-up view of the histotripsy device
Illuminate

Histotripsy: Making the Impossible Possible

Learn about the clinical histotripsy device (EdisonTM), created by Zhen Xu, Ph.D. at the University of Michigan. It's a completely non-invasive—no needles, no incision, no exposure to radiation, non-thermal—way to destroy target tissue, in this case, cancer tumors.
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Health Lab

Researchers discover urine based test to detect head and neck cancer

At-home test can detect tumor DNA fragments in urine samples, providing a non-invasive alternative to traditional blood-based biomarker tests
DNA helix technology robotic cybernetic image
Health Lab

Metabolite tells cells whether to repair DNA

Findings from researchers at the University of Michigan Health Rogel Cancer Center, published in Cancer Discovery, show how a specific nucleotide metabolite called GTP controls responses to radiation and chemotherapy in an unexpected way.
Health Lab

Hungry for more

Metabolism pathways make tumors sensitive or resistant to treatments. A collaborative group leverages these avenues to explore the growing foundation of new potential therapies
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Health Lab

Hitting the mark

University of Michigan Rogel Cancer Center researchers are unraveling its nuances, advancing enabling technologies, advocating for patients and figuring out how to ethically integrate this technology into clinical care.
News Release

Rogel awarded SPORE grant designed to further research on radiosensitization

The grant will include projects on pancreas, brain and breast cancers, and will examine each disease using a different way of overcoming radiation resistance.
blood sample
Health Lab

Early findings suggest clinical and lab-based approach critical to tracking head and neck cancer recurrence

Early findings of two studies from the University of Michigan Rogel Cancer Center shed light on new ways to anticipate recurrence in HPV-positive head and neck cancer sooner. The papers, published in Cancer and Oral Oncology, offer clinical and technological perspectives on how to measure if recurrence is happening earlier than current blood tests allow, and provide a framework for a new, more sensitive blood test that could help in this monitoring.
nanoparticles floating green blue
Health Lab

Gene therapy for brain tumor shows promising early results in humans

Research from the University of Michigan Department of Neurosurgery and Rogel Cancer Center shows promising early results that a therapy combining cell-killing and immune-stimulating drugs are safe and effective in extending survival for patients with gliomas, a highly aggressive form of brain cancer.
pink purple microscopic cells
Health Lab

Study shows new approach to target deadly form of prostate cancer

A study from the University of Michigan Rogel Cancer Center uncovers a new mechanism to explain why some prostate tumors switch from a common, treatable form to a more rare and aggressive form of prostate cancer.
gloved hand doing microplate samples
Health Lab

Study brings insight to kidney cancer with gene mutation

A study from clinicians and researchers at the University of Michigan Rogel Cancer Center reveals findings from over 800 clinical assays performed for kidney patients with MiTF family gene mutations.
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Health Lab

Study finds cancer cells use a new fuel in absence of sugar

Sugar free: investigator finds cancer cells use a new fuel in absence of sugar