Biological Chemistry Research
Asking and Answering Fundamental Questions
We explore biological phenomena at the molecular and mechanistic levels to make discoveries about life and health.
Understanding the Foundations of Life
Scientists in the Department of Biological Chemistry integrate many technologies and approaches to study the molecular processes that are the foundation for life and health. Research projects can be grouped into the four broad areas of Biochemical Signaling, Macromolecular Structure & Mechanism, Protein Processing & Folding and Regulation of Gene Expression.
Close ties and cross-appointments with the Life Sciences Institute, the Center for RNA Biomedicine, the Michigan Neuroscience Institute, the Chemical Biology Program, and the LSA departments of Biology, Biophysics, and Chemistry place Biological Chemistry at the center of the University of Michigan's strong biochemical community.
Our interdisciplinary research into the molecular mechanisms of life offers a wide variety of investigative opportunities to students, fellows, and scientific collaborators.
Research Areas
Biochemical Signaling
Probe how cells respond to changes in their environment.
Macromolecular Structure & Mechanism
Focus in on how biological macromolecules function at the molecular and atomic level.
Protein Processing & Folding
Understanding the folding, translocation, and processing of proteins is integral to modern molecular and cell biology.
Regulation of Gene Expression
Use and develop groundbreaking research techniques to uncover the mechanisms that govern gene expression.
Biological Chemistry News & Stories
Patrick O'Brien, PhD, featured in ASBMB Today
CRISPR acts as commander-in-chief for backup defenses in bacteria
Congratulations to Carmen Castillo, PhD
Scientists discover that bacteria use an understudied polymer found in all life to protect cell functions during stress
Adrian Palumbo chosen for a position in the Pharmacological Sciences Training Program