Discovery Science

Strengthening Basic Science Research & Education at the U-M Medical School
Lab member looking into microscope

There are nine fundamental research departments within Michigan Medicine. Each is dedicated to understanding the biology of the human body and biological processes to provide the foundational knowledge needed to advance treatments and cures or the implementation of such knowledge to improve medical care.

Awards & Accolades

Discover the groundbreaking work of our researchers.

Giving

Your gift supports the groundbreaking work of our researchers.

Participating Units
  • Biological Chemistry
  • Biomedical Engineering
  • Cell & Developmental Biology
  • Computational Medicine & Bioinformatics
  • Human Genetics
  • Learning Health Sciences
  • Microbiology & Immunology
  • Molecular & Integrative Physiology
  • Pharmacology
    • Scientists engaged in discussion at a research poster

    Upcoming Events

    Attend an event with our departments to connect with fellow researchers and celebrate new discoveries across the U-M Medical School.

    Explore events

    Explore the Impact of Discovery Science


    Discovery Science drives innovation, its breakthroughs forming the foundation of tomorrow's therapeutics. 

    In this video, co-chairs Beth Moore, PhD and Phyllis Hanson, PhD of the Endowment for Basic Sciences at the U-M Medical School join with some of our researchers in promoting their essential work.

    Support the research
    Discovery Science @ University of Michigan Medical School

    Learn more about Discovery Science at U-M Medical School.

    Featured News & Stories
    Purple shaded illustration of doctor listening to heart of patient on a bed
    Health Lab

    The AI is listening: Implications of machine generated clinical notes on health care

    Michigan Medicine experts argue that use of artificial intelligent scribes during health care visits should be more carefully examined .
         A stylized digital image of an X-ray of a human skeleton superimposed on a strand of DNA
    Health Lab

    Bigger data reveals the second, third and fourth switches controlling a gene

    A University of Michigan study reveals the untapped potential of the NIH-sponsored Trans-Omics for Precision Medicine, or TOPMed, program.
         layers of skin pink to yellow
    Health Lab

    Study outlines a new framework for direct cell reprogramming

    In a new paper published in the journal iScience, Lindsey Muir, Ph.D. and her lab at Michigan Medicine propose a framework for direct cell reprogramming.
         cells close up blue and green background microscope
    Health Lab

    Engineered nanoparticles sensitize gliomas to radiotherapy

    University of Michigan researchers discovered a new pathway that sensitizes mIDH1 gliomas to radiation in human and mouse mIDH1 glioma cells and mouse models, paving the way for phase 1 clinical trials in humans
         cells floating close up green blue pink
    Health Lab

    Uncovering cellular stress signal triggered by Salmonella

    In a new paper published in Infection and Immunity, researchers from the O’Riordan lab looked for causes of stress for cells infected with Salmonella. 
         Microscope images of prostate cancer cells
    Health Lab

    New drug combination may help treat advanced prostate cancer

    University of Michigan researchers found that combining BET bromodomain and DNMT inhibitors may slow the growth of treatment-resistant prostate cancer by targeting transdifferentiated tumors.