Michigan Biology Of Cardiovascular Aging

Educating Future Leaders to Run Ingenious Research

Educating and training junior faculty and future leaders to run cutting-edge research is at the heart of M-BoCA.

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Mission Statement

The mission of the Michigan Biology of Cardiovascular Aging Center is to advance scientific understanding of the mechanisms driving cardiovascular aging and age-related heart diseases. Through collaborative and inclusive research, we investigate how biological aging influences cardiovascular health, integrate insights from diverse disciplines, and foster partnerships across the scientific community. Our goal is to discover novel therapeutic strategies that improve cardiovascular outcomes and promote healthy aging for all.

Research

Michigan Biology Of Cardiovascular Aging program is made up of various research labs that share a common ground of Cardiovascular Aging research.

Education

Educating and training junior faculty and future leaders to run cutting-edge research is at the heart of M-BoCA.

People

We are focused on aging and cardiovascular disease that enhances collaborative research knowledge between team members, and others.

M-BOCA VIRTUAL SEMINAR SERIES

"From Raw RNA-seq Data to Gene Expression Matrix: Exploratory Analysis and Machine Learning Applications"

Tuesday, September 15, 2026
1:00pm-2:00pm 

Rong Tian, MD, PhD
Professor of Anesthesiology & Pain Medicine, and Bioengineering
Director of Mitochondria and Metabolism Center
University of Washington

A multidisciplinary science program to foster research collaborations, mentoring, networking, and education in the area of aging and cardiovascular disease via monthly public lecture series, visiting speakers, an annual symposium, and more.

Join us for the next M-BoCA Virtual Seminar, Tuesday, September 15, 2026 from 1:00pm-2:00pm featuring Rong Tian, MD, PhD presenting with the title "Mitochondria and Cardiac Remodeling in Heart Failure with Preserved Ejection Fraction"Please see the meeting information below.

Join us via Zoom.

Meet our Biostatistician

Liu Liu, PhD

Liu Liu, PhD

I provide bioinformatics consulting for collaborators working across regenerative biology, cellular reprogramming, functional genomics, and translational biomedical research.

My background combines 10+ years of work in cardiac regeneration, fibroblast reprogramming, iPSC differentiation, single-cell omics, computational biology, and AI/ML for therapeutic discovery.

I help investigators translate biological and clinical questions into analytical strategies, reproducible workflows, and interpretable results across transcriptomic, clinical, immune-profiling, and other high-dimensional datasets.

My consulting work supports study design, data analysis, candidate prioritization, and manuscript- and grant-ready scientific outputs, with particular strength in projects involving cell-state conversion, perturbation biology, and regenerative systems.

Liu Liu, PhD
Adjunct Associate Research Scientist, Internal Medicine

Cutting-Edge Research at the Heart of M-BoCA

Computer screen with heart and world map

Lecture Series Schedule

Explore groundbreaking insights into cardiovascular health from esteemed experts, unraveling the mysteries of heart function, disease mechanisms, and innovative therapies.

Current Events
Swirski

Annual MBoCA Symposium

Each year M-BoCA hosts a large-scale symposium to bring even greater cardiovascular and aging collaboration to the University of Michigan. This year's symposium will be held on Friday, October 2nd in the Danto Auditorium at the Frankel Cardiovascular Center. Our keynote speaker is Filip Swirski, PhD from the Icahn School of Medicine at Mount Sinai Hospital. His talk will be "Inter-Organ Communication and Cardiovascular Health". Email Bruce Skinner at [email protected] for more information and how to register.

Our Most Recent Event

A Multidisciplinary Science Program

Michigan Biology of Cardiovascular Aging (M-BoCA) is a multidisciplinary science program focused on aging and cardiovascular disease that enhances collaborative research knowledge between established investigators, team members, and others whose work and interests closely relate. Educating and training junior faculty and future leaders to run cutting-edge research is at the heart of M-BoCA.

Featured News and Events

View all M-BoCA News and Events
Rong Tian
Research News

Rong Tian, MD, PhD, will present, "Mitochondria and Cardiac Remodeling in Heart Failure with Preserved Ejection Fraction"

Rong Tian, MD, PhD, will present, "Mitochondria and Cardiac Remodeling in Heart Failure with Preserved Ejection Fraction"
Liu Liu, PhD
Research News

Liu Liu, PhD, Will Present a Mini-Symposium, “From Raw RNA-seq Data to Gene Expression Matrix: Exploratory Analysis and Machine Learning Applications”

Liu Liu, PhD, Will Present a Mini-Symposium, “From Raw RNA-seq Data to Gene Expression Matrix: Exploratory Analysis and Machine Learning Applications”
Crewe
Research News

Clair Crewe, PhD will present “The surprising functions of adipocyte extracellular vesicles"

Clair Crewe, PhD will present “The surprising functions of adipocyte extracellular vesicles" May 19, 2026