Date: Tuesday, August 15, 2023

Speaker: Jaroslava Seflova, PhD

Talk Title: "Sodium pump regulatory mechanisms"

Time: 12:00PM-1:00PM

Location: https://umich.zoom.us/j/92341148353

Date: Tuesday, July 18, 2023

Speaker: Jianrui Song, PhD

Talk Title: "Itaconate suppresses atherosclerosis by activating a Nrf2-dependent anti-inflammatory response in macrophages"

Time: 12:00PM-1:00PM

Location: https://umich.zoom.us/j/96829915961

Date: Tuesday, June 20, 2023

Speaker: Daniel Beard, PhD

Talk Title: "Metabolic and Mechanical Determinants of Reserve Cardiac Power Output"

Time: 12:00PM-1:00PM

Location: https://umich.zoom.us/j/94073785459

Date: Tuesday, May 23, 2023

Speaker: Colin Stomberski, MD, PhD

Talk Title: "Biasing protein phosphatase 2A for cardiovascular benefit"

Time: 12:00PM-1:00PM

Location: https://umich.zoom.us/j/99039588557

Date: Tuesday, April 18, 2023

Speaker: Tony Rosenzweig, MD

Talk Title: "Proteostasis Networks in Hypertrophic Cardiomyopathy "

Time: 12:00PM-1:00PM

Location: https://umich.zoom.us/j/93705196981

Date: Tuesday, March 21, 2023

Speaker: Andrea Dooley Thompson, MD, PhD

Talk Title: "Proteostasis Networks in Hypertrophic Cardiomyopathy "

Time: 12:00PM-1:00PM

Location: https://umich.zoom.us/j/92635756641

Date: Tuesday, February 21, 2023

Speaker: Nadia Sutton, MD

Talk Title: "Circulating Ectonucleotidases and Myocardial Perfusion"

Time: 12:00PM-1:00PM

Location: https://umich.zoom.us/j/96226276786

Date: Thursday, January 19, 2023

Speaker: Salim Hayek, MD

Talk Title: "From Biomarker to BioMaker: The Story of Soluble Urokinase Receptor (SuPAR) in Kidney and Cardiovascular Disease"

Time: 12:00PM-1:00PM

Location: https://umich.zoom.us/j/94397761547

2021-2022 Lecture Series schedule below:

Date: Tuesday, November 15, 2022

Speaker: Ora Singer, MD, MS

Talk Title: "Aortitis in Giant Cell Arteritis: A New Horizon in an Old Disease"

Time: 12:00PM-1:00PM

Location: https://umich.zoom.us/j/94158501935(link is external)

Date: Tuesday, September 20, 2022

Speaker: Ahmed Abdel-Latif, MD, Phd

Talk Title: "Exploring Cardiomyocyte Autonomous and Non-Autonomous Therapeutic Targets in Ischemic Heart Disease:  Translational Perspectives"

Time: 12:00PM-1:00PM

Location: https://umich.zoom.us/j/97563275755

Date: Tuesday, August 2, 2022

Speaker: Paul Tang, MBBS, Phd

Talk Title: "Metabolic reprogramming of donor hearts to improve performance"

Time: 12:00PM-1:00PM

Location: https://umich.zoom.us/j/95665855989

Date: Tuesday, July 19, 2022

Speaker: Nageswara Madamanchi, Phd

Talk Title: "Mitochondrial Oxidative Stress and Impaired Mitochondrial Dynamics in Diastolic Dysfunction"

Time: 12:00PM-1:00PM

Location: https://umich.zoom.us/j/91078013923

Date: Tuesday, April 19th, 2022

Speaker: Andre Monteiro da Rocha, Phd DVM

Talk Title: "Effects of ischemia on ventricular cardiomyocytes derived from hiPSCs carrying a mutation causative of advanced aging syndrome"

Time: 12:00PM-1:00PM

Location: https://umich.zoom.us/j/93677733299

Date: Tuesday, March 22nd, 2022

Speaker: Vittorio Sebastiano, PhD

Talk Title: “Repurposing the principles of reproduction to stall and reverse cellular aging”

Time: 12:00PM-1:00PM

Location: https://umich.zoom.us/j/91885368144

Date: Tuesday, February 15th, 2022

Speaker: C. Alberto Figueroa, PhD

Talk Title: “Comparative Study of Human and Murine Aortic Biomechanics and Hemodynamics in Vascular Aging”

Time: 12:00PM-1:00PM

Location: https://umich.zoom.us/j/95515231709

Date: Tuesday, January 18th, 2022

Speaker: Morgan Salmon, PhD

Talk Title: “Pro-Resolving Lipid Mediators and Aortic Aneurysm Formation”

Time: 12:00PM-1:00PM

Location: Zoom https://umich.zoom.us/j/93200534206

No MBoCA Lecture for December, 2021 

Date: Tuesday, November 16th, 2021

Speaker: Todd Herron, PhD

Talk Title: "Human Stem Cell Derived Cardiomyocytes and Tissues for Research and Disease Modeling"

Time: 12:00PM-1:00PM

Location: Zoom https://umich.zoom.us/j/96516244464

2019-2020 Lecture Series schedule below:

Date: Tuesday, October 1st, 2019

Speaker: Todd Herron, PhD

Talk Title: "Personalized Cardiac Disease Modeling and Medication Screening Using Human Induced Pluripotent Stem Cell Derived Cardiomyocytes"

Time: 12:00PM-1:00PM

Location: Frankel Cardiovascular Center #5321 (5th Floor Boardroom)

--

Date: Tuesday, November 19th, 2019

Speaker: C. Alberto Figueroa, PhD

Talk Title: "Data-driven Computational Modeling of Hemodynamics, Central Artery Stiffness, and Hypertension"

Time: 12:00PM-1:00PM

Location: Frankel Cardiovascular Center #5321 (5th Floor Boardroom)

--

Date: Tuesday, December 3rd, 2019

Speaker: Daniela Ponce Balbuena, PhD

Talk Title: "Cardiac Kir2.1 and NaV1.5 channels in sickness and in health together"

Time: 12:00PM-1:00PM

Location: Frankel Cardiovascular Center #5321 (5th Floor Boardroom)

--

Date: Tuesday, January 21st, 2020

Speaker: Nadia Sutton, MD

Talk Title: "Ectonucleotidases in vascular aging: spiked with experiential tips and pitfalls"

Time: 12:00PM-1:00PM

Location: Frankel Cardiovascular Center #5321 (5th Floor Boardroom)

--

Date: Tuesday, February 4th, 2020

Speaker: Daniel Lawrence, PhD

Talk Title: "Development of an Orally Active Small Molecule Inhibitor of PAI-1 for the Treatment of Fibrotic Disease"

Time: 12:00PM-1:00PM

Location: CVC Executive Conference Room, Cardiac Surgery Suite (5th Floor, #5162A)

--

Date: Tuesday, June 16, 2020

Speaker: Daniel Tyrrell, PhD

Talk title: "Mechanisms of Blood Brain Barrier Breakdown in Cerebrovascular Aging"

Time: 12:00PM-1:00PM

Zoom Link: https://umich-health.zoom.us/j/91651002116

--

Date: Tuesday, July 14, 2020

Speaker: Anna V. Mathew, MD

Talk Title: “Tryptophan Catabolism and CKD-associated Cardiovascular Disease”

Time: 12:00PM-1:00PM

Zoom Link: https://umich-health.zoom.us/j/99368088613

--

Date: Thursday, September 10, 2020

Speaker: Rosanne Rouf, MD

Talk Title: “Microenvironmental Regulation of Myocardial Function by Extracellular Fibrillin-1"

Time: 12:00PM-1:00PM

Zoom Link: https://umich-health.zoom.us/j/92925267698

--

Date: Tuesday, October 13, 2020

Speaker: Oren Rom, PhD, RD

Talk Title: “Cardiometabolic diseases at the interface between amino acid and lipid metabolism: mechanisms and potential therapies"

Time: 1:00PM-2:00PM

Zoom Link: https://umich-health.zoom.us/j/92493336725

--

Date: November 10, 2020

Speaker: Richard Mortensen, MD, PhD

Talk Title: Itaconate and Glucose Metabolism: Immune Response and Aging

Time: 12:00PM-1:00PM

Zoom Link: https://umich-health.zoom.us/j/91293189008

--

Date: POSTPONED

Speaker: Paul Tang, MD, PhD

Talk Title: TBA

Time: 12:00PM-1:00PM

Location: TBA

--

Date: POSTPONED

Speaker: David Pinsky, MD

Talk Title: TBA

Time: 12:00PM-1:00PM

Location: TBA

Date: Tuesday, January 18th, 2022

Speaker: Morgan Salmon, PhD

Talk Title: “Pro-Resolving Lipid Mediators and Aortic Aneurysm Formation”

Time: 12:00PM-1:00PM

Location: Zoom https://umich.zoom.us/j/93200534206

No MBoCA Lecture for December, 2021 

Date: Tuesday, November 16th, 2021

Speaker: Todd Herron, PhD

Talk Title: "Human Stem Cell Derived Cardiomyocytes and Tissues for Research and Disease Modeling"

Time: 12:00PM-1:00PM

Location: Zoom https://umich.zoom.us/j/96516244464

Date: Tuesday, October 2nd, 2018

Speaker: Yogen Kanthi, MD

Talk Title: "Purinergic Regulation of Venous Thrombo-Inflammation"

Time: 12:00PM-1:00PM

Location: Frankel Cardiovascular Center #5321 (5th Floor Boardroom)

--

Date: Thursday, November 29th, 2018

Speaker: L. Michel Espinoza-Fonseca, PhD

Talk Title: "Calcium pump activators for heart failure therapy"

Time: 12:00PM-1:00PM

Location: Cardiovascular Medicine Library #2722K (2nd Floor of CVC)

--

Date: Tuesday, December 4th, 2018

Speaker: Marion Hofmann Bowman, MD, PhD

Talk Title: "S100/RAGE-mediated Inflammation and modified Cholesterol Lipoproteins as mediators of vascular calcification"

Time: 12:00PM-1:00PM

Location: Frankel Cardiovascular Center #5321 (5th Floor Boardroom)

--

Date: Thursday, January 21st, 2019

Speaker: Y. Eugene Chen, MD, PhD

Talk Title: "Nitration of unsaturated fatty acids: from bench to bedside"

Time: 12:00PM-1:00PM

Location: Frankel Cardiovascular Center #5321 (5th Floor Boardroom)

--

Date: Tuesday, February 5th, 2019

Speaker: Justus Anumonwo, PhD

Talk Title: "The MAGUK Protein, Sap97: Synchronizing ‘Pacemaker Clocks’ of the Sino Atrial Node"

Time: 12:00PM-1:00PM

Location: Frankel Cardiovascular Center #5321 (5th Floor Boardroom)

--

Date: Tuesday, March 5th, 2019

Speaker: Andre Monteiro da Rocha, PhD

Talk Title: "Progeria: a laminopathy shedding light into cardiovascular aging"

Time: 12:00PM-1:00PM

Location: Frankel Cardiovascular Center #5321 (5th Floor Boardroom)

--

Date: Tuesday, April 2nd, 2019  

Speaker: Scott Soleimanpour, PhD

Talk Title: "New insights into mitochondrial quality control in pancreatic beta cells during aging and obesity"

Time: 12:00PM-1:00PM

Location: Frankel Cardiovascular Center #5321 (5th Floor Boardroom)

--

Date: Tuesday, May 7th, 2019

Speaker: Maria Papaleontiou, MD

Talk Title: "Thyroid hormones & cardiovascular risk"

Time: 12:00PM-1:00PM

Location: Frankel Cardiovascular Center #5321 (5th Floor Boardroom)

--

Date: Wednesday, May 29th, 2019

Speaker: Anthony Donato, PhD, MS

Talk Title: "Telomere uncapping induces cellular senescence and inflammation in arteries: implications for arterial aging and hypertension"

Time: 1:30PM-2:30PM

Location: Frankel Cardiovascular Center #5321 (5th Floor Boardroom)

Date: Tuesday, October 17th, 2017

Speaker: Randy Seeley, PhD

Talk Title: "Bariatric Sugery: It's not what you think it is - Molecular targets for the effects of surgery on obesity, diabetes and beyond."

Time: 12:30PM-1:30PM

Location: Frankel Cardiovascular Center #5321 (5th Floor Boardroom)

--

Date: Tuesday, November 21st, 2017

Speaker: Jun Wu, PhD

Talk Title: "Beige-specific-fat regulation in mouse and human"

Time: 12:30PM-1:30PM

Location: Frankel Cardiovascular Center #5321 (5th Floor Boardroom)

--

Date: Tuesday, December 19th, 2017

Speaker: Markus Bitzer, MD

Talk Title: "Aging-associated Glomerulopathy"

Time: 12:30PM-1:30PM

Location: Frankel Cardiovascular Center #5321 (5th Floor Boardroom)

--

Date: Tuesday, January 16th, 2018

Speaker: Charles Burant, MD, PhD

Talk Title: "Molecular basis of slowed aging by high oxidative capacity in rats and people"

Time: 12:30PM-1:30PM

Location: Frankel Cardiovascular Center #5321 (5th Floor Boardroom)

--

Date: Tuesday, February 20th, 2018

Speaker: Kanakadurga Singer, MD & Mita Varghese, PhD

Talk Title: "Sex differences in diet-induced inflammation and lipolytic responses"

Time: 12:30PM-1:30PM

Location: Frankel Cardiovascular Center #5321 (5th Floor Boardroom)

--

Date: Tuesday, March 20th, 2018

Speaker: Nadia Sutton, MD

Talk Title: "Ectonucleotidases and Vascular Aging"

Time: 12:30PM-1:30PM

Location: Frankel Cardiovascular Center #5321 (5th Floor Boardroom)

--

Date: Tuesday, April 10th, 2018

Speaker: Scott Leiser, PhD

Talk Title: "From perception to physiology: The role of stress response in aging"

Time: 12:30PM-1:30PM

Location: Frankel Cardiovascular Center #5321 (5th Floor Boardroom)

--

Date: Tuesday, May 15th, 2018

Speaker: Scott Pletcher, PhD

Talk Title: "Central Control of Aging in Drosophila"

Time: 12:30PM-1:30PM

Location: Frankel Cardiovascular Center #5321 (5th Floor Boardroom)

--

Date: Tuesday, June 19th, 2018

Speaker: Dan Tyrrell, PhD

Talk Title: "Aging enhances vascular inflammation, mitophagy, macrophage infiltration and atherosclerosis plaque necrosis, independently of metabolic dysfunction"

Time: 12:30PM-1:30PM

Location: Frankel Cardiovascular Center #5321 (5th Floor Boardroom)

Date: Friday, November 18th, 2016

Speaker: Joan Greve, PhD

Talk Title: "Murine Models are Not Immune to the Challenges Aging Imposes"

Time: 2:00PM-3:00PM

Location: Frankel Cardiovascular Center #5321 (5th Floor Boardroom)

--

Date: Monday, December 19th, 2016

Speaker: Scott Hummel, MD

Talk Title: "Heart Failure with Preserved Ejection Fraction: Salt and Sensitivity?"

Time: 12:00PM-1:00PM

Location: Cardiovascular Medicine Library #2722K (2nd Floor of CVC)

--

Date: Wednesday, January 25th, 2017

Speaker: Aleksandr Vendrov, MD & Chandrika Canugovi, PhD

Talk Title: "Mitochondrial-Specific Nox 4 Overexpression Increases Aortic Stiffening" & "Modulation of mitochondrial oxidative stress in prevention of vulnerable plaque in aged hyperlipidemic mice"

Time: 12:00PM-1:00PM

Location: Frankel Cardiovascular Center #5321 (5th Floor Boardroom)

--

Date: Thursday, February 16th, 2017

Speaker: Daniel Beard, PhD

Talk Title: "Interplay of vascular mechanics and autonomic reflexes in hypertension & "Myocardial mechano-energetic coupling in heart failure"

Time: 12:00PM-1:00PM

Location: Frankel Cardiovascular Center, Danto Auditorium

--

Date: Thursday, March 16th, 2017

Speaker: Billy Giblin, PhD

Talk Title: "Age-Associated Epigenetic Dysregulation in Mouse Heart"

Time: 3:00PM-4:00PM

Location: Biomedical Science Research Building (BSRB), Seminar Rooms A, B, C

--

Date: Tuesday, March 21st, 2017

Speaker: Preeti, Malani, MD, MS

Talk Title: "Embracing Change in Medical Publishing: An Insider's Look at JAMA"

Time: 3:00PM-4:00PM

Location: Frankel Cardiovascular Center, Danto Auditorium

--

Date: Thursday, April 13th, 2017

Speaker: Markos Koutmos, PhD

Talk Title: "RNA processing by mitochondrial RNase Ps: a new class of ribonucleases and their role in mitochondrial function"

Time: 4:00PM-5:00PM

Location: Frankel Cardiovascular Center #5321 (5th Floor Boardroom)

--

Date: Tuesday, April 18th, 2017

Speaker: Sharlene Day, MD

Talk Title: "Effects of acarbose on motor function and cardiac aging"

Time: 4:00PM-5:00PM

Location: Frankel Cardiovascular Center #5321 (5th Floor Boardroom)

--

Date: Wednesday, May 17th, 2017

Speaker: Nuo Sun, PhD

Talk Title: "Mitophagy as a regulator of cardiac function in physiological and pathophysiological conditions"

Time: 4:00PM-5:00PM

Location: Frankel Cardiovascular Center #5321 (5th Floor Boardroom)

--

Date: Monday, May 22nd, 2017

Speaker: Kaikobad Irani, MD

Talk Title: "Microbes and MicroRNAs in Cardiometabolic Diseases"

Time: 4:00PM-5:00PM

Location: Cardiovascular Medicine Library #2722K (2nd Floor of CVC)

--

Date: Wednesday, May 24th, 2017

Speaker: Mike Holinstat, PhD

Talk Title: "12-Lipoxygenase and its oxylipins represent novel regulators of platelet function and thrombosis"

Time: 4:00PM-5:00PM

Location: Cardiovascular Medicine Library #2722K (2nd Floor of CVC)

--

Date: Monday, June 19th, 2017

Speaker: Chi Fung Lee, PhD

Talk Title: "Targeting NAD+ - Sensitive Acetylation as Therapy for Mitochondria-related Diseases"

Time: 12:00PM-1:00PM

Location: Frankel Cardiovascular Center #5321 (5th Floor Boardroom)

--

Date: Wednesday, June 21st, 2017

Speaker: Richard Miller, MD, PhD

Talk Title: "Drugs that Slow Aging in Mice: The Search for Shared Mechanisms"

Time: 4:00PM-5:00PM

Location: Cardiovascular Medicine Library #2722K (2nd Floor of CVC)