National Center of Rabbit Models for Translational Research
Expanding access to gene edited rabbit models across the United States for their use in biomedical research.
Explore NCRM
The National Center of Rabbit Models for Translational Research (NCRM) was established in 2025 with a grant support from the National Institutes of Health (NIH). The NCRM's mission is to expand access to gene edited rabbit models across the United States for their use in biomedical research. We are dedicated to generating novel gene edited rabbit models with direct translational relevance to cardiovascular, ocular, neurologic, immunology and infectious diseases, genetic diseases, and other human diseases, to disseminating these models to researchers across the nation, and to providing training workshop to potential users on these novel models and related technologies.
Contact Us
NCRC B26-361S
Ann Arbor, MI 48109
New Model Requests
NCRM provides rabbit model production services to researchers in the nation.
Currently we offer conventional transgenic (random insertion), gene knockout and gene knock-in model development. The typical turnover time is 6 to 12 months for founder production. Please contact us to schedule a meeting to discuss your project.
Available Models
NCRM has produced multiple rabbit models for translational research. Researchers across the nation have also deposited their rabbit models to the Center. Please contact us to inquire the availability of available models.
Events
NCRM is excited to announce that we will host a workshop in the 2026 AALAS annual conference.
Workshop name: Genetically Modified Rabbit Production and Colony Management Techniques
Workshop description: Genetically modified (GM) rabbits offer great potential as translationally relevant models of human disease for many biomedical research applications. Thanks to their evolutionary closeness to humans, long lifespan, medium body size, and favorable reproduction features, GM rabbits represent a new optimal laboratory friendly animal model for biomedical advancement.
The newly created, NIH funded, National Center of Rabbit Models for Translational Research (NCRM) was established at the University of Michigan to expand access of US researchers to GM rabbit models. The NCRM provides a centralized source for generating GM rabbit models, cryopreservation, bio-banking, and distribution of rabbit models, and the training of research staff on the care, maintenance, and related technologies required to successfully maintain a GM rabbit colony.
The workshop will include lecture education, video based demonstrations, and hands on learning opportunities to participants on topics including methods for creating GM rabbit models, rabbit breeding, husbandry and veterinary care tactics in a reproductive rabbit colony.
The overall mission of this workshop is to provide education and training to researchers, veterinarians, veterinary technicians, and husbandry technicians on the methods required for the successful generation and maintenance of a genetically modified rabbit colony.
Sponsor: National Center of Rabbit Models for Translational Research (NCRM)
Contact Information for Workshop Leaders:
Zach Freeman, DVM, DACLAM: [email protected]
Brooke Pallas, DVM, DACLAM: [email protected]
The AALAS conference site: https://www.aalas.org/meeting/main
