In the Shavit laboratory we perform “clinically directed basic research” in the field of hemostatic and thrombotic disorders.
Welcome to the Shavit Laboratory at the University of Michigan. We study the genetics of human blood and cardiovascular disorders using zebrafish and mouse models. We are developing large scale zebrafish mutagenesis screens to identify genetic and chemical modifiers of these disorders. This will be followed by investigation of these modifiers in mouse models and human populations.
Our laboratory is a member of the Departments of Pediatrics and Human Genetics, Cardiovascular Center, and Comprehensive Cancer Center.
Henry and Mala Dorfman Family Professor of Pediatric Hematology/Oncology
Professor of Pediatrics
Professor of Human Genetics
Patients with deficiencies of particular blood coagulation factors are often labeled with bleeding or clotting disorders, yet often have no phenotype. On the other hand there are patients with phenotypes out of proportion to their laboratory clotting factor profile. Thus we are often unable to predict an individual patient’s risk with any useful degree of accuracy.
8200 MSRB III 1150 West Medical Center Drive
Ann Arbor, MI 48109-5646 USA
Email: [email protected]
Join Us!
Graduate student and postdoctoral fellow positions are available
Contact [email protected] for more information
