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Key Publications
- Zou W. Immune regulation in the tumor microenvironment and its relevance in cancer therapy. Cellular & molecular immunology. 2022;19(1):1-2.
- Sun D, Wang W, Guo F, Pitter MR, Du W, Wei S, et al. DOT1L affects colorectal carcinogenesis via altering T cell subsets and oncogenic pathway. Oncoimmunology. 2022;11(1):2052640.
- Liao P, Wang W, Wang W, Kryczek I, Li X, Bian Y, et al. CD8(+) T cells and fatty acids orchestrate tumor ferroptosis and immunity via ACSL4. Cancer cell. 2022;40(4):365-78.e6.
- Li S, Yu J, Huber A, Kryczek I, Wang Z, Jiang L, et al. Metabolism drives macrophage heterogeneity in the tumor microenvironment. Cell reports. 2022;39(1):110609.
- Holcomb EA, Zou W. A forced marriage of IL-2 and PD-1 antibody nurtures tumor-infiltrating T cells. The Journal of clinical investigation. 2022;132(3).
- Du W, Frankel TL, Green M, Zou W. IFNγ signaling integrity in colorectal cancer immunity and immunotherapy. Cellular & molecular immunology. 2022;19(1):23-32.
- Zhou J, Kryczek I, Li S, Li X, Aguilar A, Wei S, et al. The ubiquitin ligase MDM2 sustains STAT5 stability to control T cell-mediated antitumor immunity. Nature immunology. 2021;22(4):460-70.
- Zhao K, Zhang Q, Flanagan SA, Lang X, Jiang L, Parsels LA, et al. Cytidine Deaminase APOBEC3A Regulates PD-L1 Expression in Cancer Cells in a JNK/c-JUN-Dependent Manner. Molecular cancer research : MCR. 2021;19(9):1571-82.
- Yu J, Green MD, Li S, Sun Y, Journey SN, Choi JE, et al. Liver metastasis restrains immunotherapy efficacy via macrophage-mediated T cell elimination. Nature medicine. 2021;27(1):152-64.
- Xia H, Green DR, Zou W. Autophagy in tumour immunity and therapy. Nature reviews Cancer. 2021;21(5):281-97.
- Certain gene signaling rewires tumors after immunotherapy
- Oncogene activation during immunotherapy triggers cancer hyperprogression
- Researchers find natural mechanism to sensitize cancer to immunotherapy
- LIMITing tumours with an immunogenic lncRNA
- Liver metastases inhibit immunotherapy efficacy
- Liver metastases cultivate an immune desert
- Liver metastases siphon T cells and blunt immunotherapy responses
- Cancer immunotherapy: Macs in the middle
- Liver Metastasis Irradiation Can Restore Immunotherapeutic Responsiveness
- Subversion of calreticulin exposure as a strategy of immune escape
- Turning cold tumors into hot tumors by improving T-cell infiltration
- How a Little-Known Glycoprotein Blocks a Cancer Cell’s Immune Response
- Glycoprotein Revealed to Be a Barrier against Cancer Immunotherapy
- Stanniocalcin 1 reversely correlates with checkpoint therapy efficacy
Featured News & Stories
Health Lab
Certain gene signaling rewires tumors after immunotherapy
For some patients, immunotherapy furthers tumor progression instead of halting it. What distinguishes those who benefit from those who don’t?
Health Lab
Researchers find natural mechanism to sensitize cancer to immunotherapy
A study defines how a type of cell death occurs from a protein and fatty acid found inside the body.
Health Lab
How a Little-Known Glycoprotein Blocks a Cancer Cell’s Immune Response
Targeting this inside-the-cell checkpoint could potentially improve response to cancer immunotherapy.
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