stock photo of a cancer cell

Cancer Genetics

Over the past two decades, the study of cancer genetics has provided new insights into the biological diversity of human cancers through high-throughput technologies. Research in this area has improved our understanding of the diversity of somatic variation in DNA and how these sequence changes (as well as epigenetic changes) lead to oncogenic phenotypes. 

Cancer genetics can be subdivided into three main areas of study: analysis of patient populations; the impact chromosome biology on phenotypes; and mutagenesis and the impact of variation on gene function. Through these studies, we obtain knowledge on the molecular underpinnings of cancer and avenues through which therapeutics may be developed. Please browse the profiles of the cancer genetics faculty below to explore the research of individual laboratories.

Principal Investigators

Eric fearon

Eric R Fearon

Emanuel N Maisel Professor of Oncology
Director, University of Michigan Rogel Cancer Center
Associate Dean for Cancer Programs
Professor of Internal Medicine
Professor of Pathology
Professor of Human Genetics
Medical School
Thomas Glover

Thomas W Glover

Professor of Human Genetics
Professor of Pediatrics
Professor of Pathology, Medical School
Jacob Kitzman headshot

Jacob Kitzman, PhD

Associate Professor of Human Genetics
Associate Chair, Department of Human Genetics
Associate Professor of Computational Medicine and Bioinformatics
Medical School
Jun Li, PhD

Jun Li, PhD

Adjunct Professor of Human Genetics
Medical School
portrait of Agnieszka Lukaszewicz

Agnieszka Lukaszewicz

Assistant Professor of Human Genetics
Medical School
Gotham narla

Goutham, Narla, MD, PhD

Louis Newburgh Research Professor of Internal Medicine
Professor of Internal Medicine
Professor of Human Genetics and Program Assistant
Internal Medicine
Medical School
Gilber Omenn

Gilbert S Omenn, MD, PhD

Harold T Shapiro Distinguished University Professor of Medicine
Professor of Computational Medicine and Bioinformatics
Professor of Internal Medicine
Professor of Human Genetics
Medical School
Professor of Environmental Health Sciences
School of Public Health
JoAnn Sekiguchi

JoAnn M Sekiguchi, PhD

Associate Professor of Internal Medicine
Associate Professor of Human Genetics and Program Director
Human Genetics
Medical School
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Thomas E Wilson, MD, PhD

Legacy Professor of Pathology Research
Professor of Pathology
Professor of Human Genetics
Associate Medical Director, Molecular Diagnostics Laboratory and Program Assistant
MGP Fellowship Director
Medical School