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DNA Recombination & Repair

DNA recombination is process that facilitates propagation of the genome across generations and that provides variation within a species. DNA repair is a mechanism for cells to repair damage to DNA caused by internal or external forces in order to maintain genome stability. Our laboratories use ground-breaking technologies to define the molecular machinery involve in DNA recombination and repair, and to determine the source and quantity of genomic variation. These studies have applications to foundational knowledge in molecular and cellular biology, for understanding disease mechanisms including cancer, and for developing technologies applicable to both basic science and therapeutics. 

Please browse the profiles of the faculty below to explore the research of individual laboratories.

Principal Investigators

Thomas Glover

Thomas Glover, PhD, FACMG

Professor of Human Genetics
Professor of Pediatrics
Professor of Pathology, Medical School
Michelle Hays

Michelle J Hays, PhD

Assistant Professor of Human Genetics, Medical School
Jacob Kitzman headshot

Jacob Kitzman, PhD

Professor of Human Genetics
Professor of Computational Medicine and Bioinformatics, Medical School
portrait of Agnieszka Lukaszewicz

Agnieszka Lukaszewicz, PhD

Assistant Professor of Human Genetics, Medical School
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John V Moran, PhD

Gilbert S Omenn Legacy Professor of Human Genetics
Professor of Human Genetics
Professor of Internal Medicine
Program Director, PhD Graduate Program in Genetics and Genomics, Medical School
JoAnn Sekiguchi

JoAnn M Sekiguchi, PhD

Associate Professor of Internal Medicine
Associate Professor of Human Genetics
Program Director, Human Genetics, Medical School
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Thomas E Wilson, MD, PhD

Legacy Professor of Pathology Research
Professor of Pathology
Professor of Human Genetics
Associate Medical Director, Molecular Diagnostics Laboratory
Program Assistant
MGP Fellowship Director, Medical School