illuminated cells under a microscope

Epigenetics

Epigenetics is the study of how chemical modifications (e.g., DNA methylation and histone modification) of genes alters cellular biology; this field has transformed the way we think about genomes. 

Epigenetic changes in DNA control gene activity without changing DNA sequences and are important for regulating gene expression. These mechanisms are involved in the regulation of all biological processes in the body from conception to death and thus are a major area of study in genetics and genomics. Our researchers study the effects of epigenetic modifications on genome function and how errors in this process cause human genetic disease. 

Please browse the profiles of the Epigenetics faculty below to explore the research of individual laboratories.

Principal Investigators

Stephanie Bielas

Stephanie Bielas, PhD

Morton S and Henrietta K Sellner Professor of Human Genetics
Professor of Human Genetics
Professor of Pediatrics
Medical School
Alan Boyle

Alan P Boyle, PhD

Professor of Computational Medicine and Bioinformatics
Professor of Human Genetics
Medical School
portrait of Margit Burmeister

Margit Burmeister, PhD

Associate Chair, Department of Computational Medicine and Bioinformatics
Program Director, Bioinformatics Graduate Program
Professor of Human Genetics
Professor of Psychiatry
Research Professor, Michigan Neuroscience Institute and Professor of Computational Medicine and Bioinformatics
Medical School
Saher "Sue" Hammoud

Saher Sue Hammoud, PhD

Associate Professor of Human Genetics
Associate Professor of Urology
Associate Professor of Obstetrics and Gynecology
Medical School
portrait of Shigeki Iwase

Shigeki Iwase PhD

Professor of Human Genetics
Professor of Pediatrics
Medical School
Sundeep Kalantry, PhD

Sundeep Kalantry

Professor of Human Genetics
Medical School
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John V Moran

Professor of Human Genetics
Professor of Human Genetics
Professor of Internal Medicine and Program Director
PhD Graduate Program in Genetics and Genomics
Medical School
Steven Parker

Stephen CJ Parker, PhD

Professor of Computational Medicine and Bioinformatics
Professor of Human Genetics, Medical School
Professor of Biostatistics, School of Public Health
Rajesh Rao, MD

Rajesh C Rao, MD

Leonard G Miller Professor of Ophthalmology and Visual Sciences
Associate Professor of Ophthalmology and Visual Sciences
Associate Professor of Pathology
Associate Professor of Human Genetics
Medical School
profile-peter-todd-2014

Peter K Todd, MD, PhD

Chester and Anne Alecks Sackett Endowed Professor
Professor of Neurology
Associate Chair for Research
Department of Neurology
Medical Director, Neurology
Professor of Human Genetics
Medical School