illuminated cells under a microscope

Epigenetics

Epigenetics is the study of how chemical modifications (e.g., DNA methylation and histone modification) of genes alters cellular biology; this field has transformed the way we think about genomes. 

Epigenetic changes in DNA control gene activity without changing DNA sequences and are important for regulating gene expression. These mechanisms are involved in the regulation of all biological processes in the body from conception to death and thus are a major area of study in genetics and genomics. Our researchers study the effects of epigenetic modifications on genome function and how errors in this process cause human genetic disease. 

Please browse the profiles of the Epigenetics faculty below to explore the research of individual laboratories.

Principal Investigators

Stephanie Bielas

Stephanie Bielas, PhD

Morton S and Henrietta K Sellner Professor of Human Genetics
Professor of Human Genetics
Professor of Pediatrics
Alan Boyle

Alan P Boyle, PhD

Professor of Computational Medicine and Bioinformatics
Professor of Human Genetics, Medical School
portrait of Margit Burmeister

Margit Burmeister, PhD

Associate Chair, Department of Computational Medicine and Bioinformatics
Program Director, Bioinformatics Graduate Program
Professor of Human Genetics
Professor of Psychiatry
Research Professor, Michigan Neuroscience Institute
Professor of Computational Medicine and Bioinformatics, Medical School
Saher "Sue" Hammoud

Sue S Hammoud, PhD

Associate Director of Cellular and Molecular Biology
Associate Professor of Human Genetics
Associate Professor of Urology
Associate Professor of Obstetrics and Gynecology, Medical School
portrait of Shigeki Iwase

Shigeki Iwase, PhD

Professor of Human Genetics
Professor of Pediatrics, Medical School
Sundeep Kalantry, PhD

Sundeep Kalantry, PhD

Professor of Human Genetics, Medical School
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John V Moran, PhD

Gilbert S Omenn Legacy Professor of Human Genetics
Professor of Human Genetics
Professor of Internal Medicine
Program Director, PhD Graduate Program in Genetics and Genomics, Medical School
Steven Parker

Stephen CJ Parker, PhD

Professor of Computational Medicine and Bioinformatics
Professor of Human Genetics, Medical School
Professor of Biostatistics, School of Public Health
Rajesh Rao, MD

Rajesh C Rao, MD

Leonard G Miller Professor of Ophthalmology and Visual Sciences
Associate Professor of Ophthalmology and Visual Sciences
Associate Professor of Pathology
Associate Professor of Human Genetics, Medical School
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Peter K Todd, MD, PhD

Chester and Anne Alecks Sackett Endowed Professor
Professor of Neurology
Associate Chair for Research, Department of Neurology
Medical Director, Neurology
Professor of Human Genetics, Medical School