Angeles Lab Publications

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Key Publications

 

  1. Shafer AM, Kenna E, Golden LAF, Elhossiny AM, Perry KD, Wilkowski J, Yan W, Kaczkofsky B, McGue J, Bresler SC, Courtney AH, Dalman JM, Galban CJ, Jiang W, Espinoza CE, Chugh R, Iyer MK, Frankel TL, Pasca di Magliano M, Dlugosz AA, Angeles CV. Immunocompetent Murine Models Recapitulate the Heterogeneous Tumor-Immune Microenvironment of Human Liposarcoma. Clinal Cancer Research, 1 December 2025; 31 (23): 5078–5095. 
  2. Bresler SC, Gosnell HL, Ko JS, Angeles CV, Ronen S, Billings SD, Patel RM. Subcutaneous Leiomyosarcoma: An Aggressive Malignancy Portending a Significant Risk of Metastasis and Death. Am J Surg Pathol. 2023 Dec 1;47(12):1417-1424. doi: 10.1097/PAS.0000000000002126. Epub 2023 Sep 19. PubMed PMID: 37727934.
  3. Du W, Menjivar RE, Donahue KL, Kadiyala P, Velez-Delgado A, Brown KL, Watkoske HR, He X, Carpenter ES, Angeles CV, Zhang Y, Pasca di Magliano M. WNT signaling in the tumor microenvironment promotes immunosuppression in murine pancreatic cancer. J Exp Med. 2023 Jan 2;220(1). doi: 10.1084/jem.20220503. Epub 2022 Oct 14. PubMed PMID: 36239683; PubMed Central PMCID: PMC9577101.
  4. Angeles CV, Velez A, Rios J, Laxa B, Shum D, Ruiz PD, Shen Y, Ostrovnaya I, Gularte-Mérida R, Nacev BA, Dickson MA, Djaballah H, Okada T, Singer S. A High-Content Screen for C/EBPα Expression Identifies Novel Therapeutic Agents in Dedifferentiated Liposarcoma. Clin Cancer Res. 2022 Jan 1;28(1):175-186. doi: 10.1158/1078-0432.CCR-19-2486. Epub 2021 Oct 19. PubMed PMID: 34667024; PubMed Central PMCID: PMC9265140.
  5. Molodtsov AK, Khatwani N, Vella JL, Lewis KA, Zhao Y, Han J, Sullivan DE, Searles TG, Preiss NK, Shabaneh TB, Zhang P, Hawkes AR, Malik BT, Kolling FW 4th, Usherwood EJ, Wong SL, Phillips JD, Shirai K, Angeles CV, Yan S, Curiel TJ, Huang YH, Cheng C, Turk MJ. Resident memory CD8(+) T cells in regional lymph nodes mediate immunity to metastatic melanoma. Immunity. 2021 Sep 14;54(9):2117-2132.e7. doi: 10.1016/j.immuni.2021.08.019. PubMed PMID: 34525340; PubMed Central PMCID: PMC9015193.
  6. Vella JL, Molodtsov A, Angeles CV, Branchini BR, Turk MJ, Huang YH. Dendritic cells maintain anti-tumor immunity by positioning CD8 skin-resident memory T cells. Life Sci Alliance. 2021 Oct;4(10). doi: 10.26508/lsa.202101056. Print 2021 Oct. PubMed PMID: 34362825; PubMed Central PMCID: PMC8356251.
  7. Han J, Zhao Y, Shirai K, Molodtsov A, Kolling FW, Fisher JL, Zhang P, Yan S, Searles TG, Bader JM, Gui J, Cheng C, Ernstoff MS, Turk MJ, Angeles CV. Resident and circulating memory T cells persist for years in melanoma patients with durable responses to immunotherapy. Nat Cancer. 2021 Mar;2(3):300-311. doi: 10.1038/s43018-021-00180-1. Epub 2021 Mar 24. PubMed PMID: 34179824; PubMed Central PMCID: PMC8223731.
  8. Han J, Khatwani N, Searles TG, Turk MJ, Angeles CV. Memory CD8(+) T cell responses to cancer. Semin Immunol. 2020 Jun;49:101435. doi: 10.1016/j.smim.2020.101435. Epub 2020 Nov 30. Review. PubMed PMID: 33272898; PubMed Central PMCID: PMC7738415.

  9. Gene Expression Profile-Based Test to Predict Melanoma Sentinel Node Status: The MERLIN_001 Study.

  10. Hieken TJ, Egger ME, Angeles CV, Hyngstrom JR, Burke EE, Lowe MC, Beasley GM, Bartlett EK, Bresler SC, Harms KL, Zager JS, Lehman JS, Wasif N, Bagaria SP, McMasters KM, Wada DA, Pandalai P, Delman KA, Lee J, Busam KJ, Messina JL, Sondak VK. JAMA Surg. 2025 Dec 1;160(12):1358-1366. doi: 10.1001/jamasurg.2025.4399.

  11. Vaccines in Melanoma: Past, Present, and Future. Janes LA, Haykal T, Angeles CV. Surg Oncol Clin N Am. 2025 Jul;34(3):411-421. doi: 10.1016/j.soc.2025.01.004. Epub 2025 Feb 21.

In the News

Dr. Angeles’ 2021 publication as co-corresponding/senior author in Nature Cancer was groundbreaking, revealing that patients with metastatic melanoma who develop vitiligo during treatment with immunotherapy maintain long-term immunological memory from the time of primary melanoma.

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