Humphries Lab
Dr. Brock Humphries
The Humphries lab studies cell signaling in tumor recurrence and metastasis. We use our expertise in cell biology and molecular imaging to uncover the mechanisms that contribute to cancer cell heterogeneity, including mitochondrial morphology, cell metabolism, and interactions with the extracellular matrix. Ultimately, we aim to utilize the new information we find out about these processes and transition them into targeted therapies for cancer. Please explore our website for more information.
Explore the Humphries Lab
Undergraduate Research Opportunities in the Humphries Lab
Undergraduates interested in my lab and research are welcome year-round.
We are seeking students who will assist with the construction and testing of/in cell-based and mouse models of breast cancer. Duties include cell culture, cell assay seeding, cell and tissue staining, and assisting with mouse colony management, animal imaging, and animal surgeries. We value collaborative thinking, and students will train and work closely with a diverse, interactive team of undergraduate and PhD students, postdocs and faculty members. The first three months of training will begin with an online volunteer arrangement, with hourly pay and in-person work after successful completion of the training phase. Approximate time commitment is 6-10 hrs per week during the academic year.
Collaborators
Center for Molecular Imaging
University of Michigan
The Center for Molecular Imaging is a state-of-the-art facility aimed at providing the research community with the latest imaging Instruments. CMI is located at the Biomedical Science Research Building and is a shared resource aimed at providing state-of-the-art imaging services for the research community.
Gary & Kathy Luker Lab
University of Michigan
The Luker lab studies functions of cell signaling in primary and metastatic cancer. Their multidisciplinary group combines expertise in medicine, biology, and engineering to uncover the mechanisms by which biochemical events in the tumor microenvironment, including chemokine signaling, metabolic regulation, and extracellular matrix interactions regulate the disease progression and response to therapy.
Mitra Aliabouzar Lab
University of Michigan
The Aliabouzar Lab aims to develop ultrasound-based technologies for micron-scale tissue characterization. More broadly, the lab investigates how ultrasound-induced bubbles can be used to probe into the viscoelasticity of the surrounding medium.
Mario Fabiilli Lab
University of Michigan
The Fabiilli Lab develops biomaterials that enable the controlled delivery of therapeutic molecules (e.g., proteins, DNA) using focused ultrasound. The use of focused ultrasound enables us to control the localization of a therapeutic agent in both space and time. Non-invasive ultrasound also enables active control of drug release and uptake, which is unlike conventional drug formulations or delivery techniques. Our goal is to improve the efficacy and mitigate toxicity of various classes of therapeutic agents while also enabling personalization of a drug therapy based on patient response.
Contact Us
Brock Humphries, PhD
A698 Biomedical Sciences Research Building
Ann Arbor, MI 48109
