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Recent Publications
Explore the latest publications from our lab.
- Mitochondrial Metabolism and Dynamics in Pancreatic Beta Cell Glucose Sensing. Guy A. Rutter et al, Biochem J. 2023
- Reciprocal Regulatory Balance Within the CLEC16A-RNF41 Mitophagy Complex Depends on an Intrinsically Disordered Protein Region. Morgan A. Gingerich et al, JBC. 2023
- An Intrinsically Disordered Protein Region Encoded by the Human Disease Gene CLEC16A Regulates Mitophagy, Gingerich MA et al, Autophagy. 2022
- Mitofusin 1 and 2 Regulation of Mitochondrial DNA Content Is a Critical Determinant of Glucose Homeostasis, Sidarala V et al, Nat Commun. 2022
- New Aspects of Diabetes Research and Therapeutic Development, Satin LS et al, Pharmacol Rev. 2021
- A Selective Look at Autophagy in Pancreatic β-Cells, Pearson GL et al, Diabetes. 2021
- Mitophagy Protects Beta Cells from Inflammatory Damage in Diabetes, Sidarala V et al, JCI Insight. 2020.
- Clarifying the function of genes at the chromosome 16p13 locus in type 1 diabetes: CLEC16A
and DEXI, Gingerich MA et al, Genes Immun. 2019 - Visualization of endogenous mitophagy complexes in situ in human pancreatic beta cells utilizing proximity ligation assay, Pearson G and Soleimanpour SA, J Vis Exp 2019
- Transition from pediatric to adult care in emerging adults with type 1 diabetes: a blueprint for effective receivership, Iyengar J et al, Clin Diabetes Endocrinol 2019
- The E3 ubiquitin ligase parkin is dispensable for metabolic homeostasis in murine pancreatic beta cells and adipocytes, Corsa CAS et al, J Biol Chem 2019
- A ubiquitin-dependent mitophagy complex maintains mitochondrial function and insulin secretion in beta cells, Pearson G and Soleimanpour SA, Autophagy 2018
- Clec16a, Nrdp1, and USP8 form a ubiquitin-dependent tripartite complex that regulates beta cell mitophagy, Pearson G et al, Diabetes 2018
- Diabetes susceptibility genes Pdx1 and Clec16a function in a pathway regulating mitophagy in beta cells, Soleimanpour SA et al, Diabetes 2015
- Mitochondrial regulation of beta cell function: maintain the momentum for insulin release, Kaufman B et al, Mol Aspects Med 2015
- The diabetes susceptibility gene Clec16a regulates mitophagy, Soleimanpour SA et al, Cell 2014
- The pancreatic beta cell and type 1 diabetes: innocent bystander or active participant? Soleimanpour SA and Stoffers DA, Trends Endocrinol Metab 2013