Publications of the Soleimanpour Lab

• LONP1 Regulation of Mitochondrial Protein Folding Provides Insight into Beta Cell Failure in Type 2 Diabetes. Li J, et al. Nature Metabolism, 2025.

• Retrograde Mitochondrial Signaling Governs the Identity and Maturity of Metabolic Tissues. Walker EM, Pearson GL, et al, Science. 2025
• Untangling the Genetics of Beta Cell Dysfunction and Death in Type 1 Diabetes. Robertson CC, Elgamal RM, Henry-Kanarek BA, et al, Molecular Metabolism. 2024
• Complementary Approaches to Interrogate Mitophagy Flux in Pancreatic β-Cells. Levi-D'Ancona E, et al, JoVE. 2023
• Protein Disorder in the Regulatory Control of Mitophagy. Mikhail and Soleimanpour, Autophagy Reports. 2023
• Mitochondrial Metabolism and Dynamics in Pancreatic Beta Cell Glucose Sensing. Guy A. Rutter et al, Biochem J. 2023
• Reciprocal Regulatory Balance Within the CLEC16A-RNF41 Mitophagy Complex Depends on an Intrinsically Disordered Protein Region. Morgan A. Gingerich et al, JBC. 2023
• An Intrinsically Disordered Protein Region Encoded by the Human Disease Gene CLEC16A Regulates Mitophagy, Gingerich MA et al, Autophagy. 2022
• Mitofusin 1 and 2 Regulation of Mitochondrial DNA Content Is a Critical Determinant of Glucose Homeostasis, Sidarala V et al, Nat Commun. 2022
• New Aspects of Diabetes Research and Therapeutic Development, Satin LS et al, Pharmacol Rev. 2021
• A Selective Look at Autophagy in Pancreatic β-Cells, Pearson GL et al, Diabetes. 2021
• Mitophagy Protects Beta Cells from Inflammatory Damage in Diabetes, Sidarala V et al, JCI Insight. 2020.
• Clarifying the function of genes at the chromosome 16p13 locus in type 1 diabetes: CLEC16A
  and DEXI, Gingerich MA et al, Genes Immun. 2019
• Visualization of endogenous mitophagy complexes in situ in human pancreatic beta cells utilizing proximity ligation assay, Pearson G and Soleimanpour SA, J Vis Exp 2019
• Transition from pediatric to adult care in emerging adults with type 1 diabetes: a blueprint for effective receivership, Iyengar J et al, Clin Diabetes Endocrinol 2019
• The E3 ubiquitin ligase parkin is dispensable for metabolic homeostasis in murine pancreatic beta cells and adipocytes, Corsa CAS et al, J Biol Chem 2019
• A ubiquitin-dependent mitophagy complex maintains mitochondrial function and insulin secretion in beta cells, Pearson G and Soleimanpour SA, Autophagy 2018
• Clec16a, Nrdp1, and USP8 form a ubiquitin-dependent tripartite complex that regulates beta cell mitophagy, Pearson G et al, Diabetes 2018

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