a person pointing at a poster

Viral Pathogens

DNA and RNA viruses can cause acute and persistent infections in humans and model organisms.

At the University of Michigan Medical School Department of Microbiology & Immunology, we actively research basic molecular virology, genetics, and pathogenesis of these viruses.

Learn more about Virology at Michigan, a website that lists faculty and labs interested in viruses across U-M.

Areas of Investigation

Specific areas of investigation include:

  • Virus entry, assembly and egress
  • Genetic determinants of virulence
  • Viral RNA replication
  • Viral genome recombination
  • Intracellular trafficking of viruses
  • Viral oncogenesis
  • Gene therapy vectors
  • Mechanisms of immune evasion
  • Innate and adaptive immune responses to viruses
  • Imaging of live virally infected mice
  • Host factors contributing to virus susceptibility

Viruses currently being studied:

  • DNA viruses: adenoviruses, BKV, and herpesviruses
  • Retroviruses: HIV and murine leukemia virus
  • RNA viruses: noroviruses, influenza virus, poliovirus, hepatitis C virus, dengue virus and emerging bunyaviruses

Faculty researching Viral Pathogens

Kathleen L. Collins

Kathleen Collins, MD, PhD

Professor of Internal Medicine
Professor of Microbiology and Immunology
Associate Dean for Physician Scientist Education and Training
Medical School
imperiale-mike

Michael J Imperiale, PhD

Arthur F Thurnau Professor Emeritus
Professor Emeritus of Microbiology and Immunology
Medical School
Philip D. King

Philip D King, PhD

Professor of Microbiology and Immunology
Medical School
Denise E. Kirschner

Denise E Kirschner, PhD

Professor of Microbiology and Immunology
Medical School
Adam Lauring

Adam Lauring, MD, PhD

Lydia DeWitt Collegiate Professor of Internal Medicine
Professor of Internal Medicine
Section Head, Internal Medicine
Professor of Microbiology and Immunology
Medical School
Professor of Ecology and Evolutionary Biology
College of Literature, Science, and the Arts
Bethany B. Moore

Bethany Moore, PhD

Nancy Walls Professor of Microbiology and Immunology
Chair, Department of Microbiology and Immunology
Professor of Microbiology and Immunology and Professor of Internal Medicine
Medical School
Akira Ono

Akira Ono, PhD

Associate Chair, Department of Microbiology and Immunology
Professor of Microbiology and Immunology
Medical School
Malini Raghavan

Malini Raghavan, PhD

Nancy Walls Research Professor of Microbiology and Immunology
Professor of Microbiology and Immunology, Medical School
Katherine Spindler

Katherine R Spindler, PhD

Professor Emerita of Microbiology and Immunology
Medical School
headshot of Andrew Tai

Andrew W Tai, MD, PhD

Associate Professor of Internal Medicine
Associate Professor of Microbiology and Immunology
Assistant Dean for Early Medical Education
Medical School
headshot of Alice-Telesnitsky

Alice Telesnitsky, PhD

Professor of Microbiology and Immunology
Medical School
Jason B. Weinberg

Jason B Weinberg, MD

James L Wilson M.D. Research Professor of Pediatrics
Associate Professor of Pediatrics
Associate Professor of Microbiology and Immunology
Pediatric Infectious Diseases and Division Director
Infectious Diseases
Medical School
wobus-christiane

Christiane Wobus, PhD

Associate Professor of Microbiology and Immunology
Medical School