Heart Failure & Cardiomyopathy Working Group

The Cardiomyopathy and Heart Failure Working Group is composed of investigators interested in the mechanisms of genetic and acquired heart disease.  Researchers in our group are exploring the cellular dysfunction and adverse cardiac remodeling in hypertrophic and dilated cardiomyopathy, as well as acquired form of heart disease resulting from hypertension or underlying coronary heart disease, with the goal of developing effective new therapies for disease prevention.  A wide variety of laboratory approaches are being used including stem cell derived human heart tissues in culture, rodent animal models, human patient tissues and clinical data, and computational modeling.