Heart Failure & Cardiomyopathy Working Group

Three greeters sit at the large circular CVC welcome desk

Exploring Adverse Cardiac Remodeling

The Working Group is composed of investigators interested in the mechanisms of genetic and acquired heart disease. 

Working Group Focus

Hypertrophic cardiomyopathy, dilated cardiomyopathy, heart failure, cardiac hypertrophy, cardiac injury, cardiac remodeling, fibrosis.

The Cardiomyopathy and Heart Failure Working Group is composed of investigators interested in the mechanisms of genetic and acquired heart disease.  Researchers in our group are exploring the cellular dysfunction and adverse cardiac remodeling in hypertrophic and dilated cardiomyopathy, as well as acquired form of heart disease resulting from hypertension or underlying coronary heart disease, with the goal of developing effective new therapies for disease prevention.  A wide variety of laboratory approaches are being used including stem cell derived human heart tissues in culture, rodent animal models, human patient tissues and clinical data, and computational modeling.  

Working Group Members

Daniel E. Michele

Daniel E Michele

John A Jacquez Collegiate Professor of Physiology
Chair, Department of Molecular and Integrative Physiology
Professor of Molecular and Integrative Physiology
Professor of Internal Medicine
Program Director, Molecular and Integrative Physiology, Medical School
portrait of Ahmed Abdel-Latif

Ahmed Abdel-latif

Research Professor
Clinical Professor of Internal Medicine
Program Director, Internal Medicine, Medical School
Daniel A. Beard

Daniel A Beard

Carl J Wiggers Legacy Professor of Cardiovascular Physiology
Professor of Molecular and Integrative Physiology
Director Graduate Studies, Molecular and Integrative Physiology
Professor of Internal Medicine
Professor of Emergency Medicine, Medical School
Professor of Biomedical Engineering, Medical School and College of Engineering
Matthew Brody headshot

Matthew Brody, PhD

Associate Professor of Pharmacology
Associate Professor of Internal Medicine, Medical School
Brian Carlson

Brian Carlson

Research Associate Professor, Molecular and Integrative Physiology, Medical School
 L Michel M Espinoza-Fonseca

L Michel Espinoza-Fonseca, PhD

Associate Professor of Internal Medicine, Medical School
goonewardena-sascha

Sascha Goonewardena

Associate Professor of Internal Medicine, Medical School
Adam Helms

Adam Helms, MD

Associate Professor of Internal Medicine
Associate Professor of Molecular and Integrative Physiology, Medical School
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Nageswara Madamanchi

Research Scientist, Internal Medicine, Medical School
Richard Mortensen, MD, PhD

Richard M Mortensen

Professor of Molecular and Integrative Physiology
Professor of Internal Medicine, Medical School
 Anthony Rosenzweig, MD

Anthony Rosenzweig, MD

Stanley and Judith Frankel Professor of Heart and Brain Health
Professor of Internal Medicine
Professor of Pharmacology
Center Director, MM Institute for Heart and Brain Health, Medical School
Yatrik M. Shah

Yatrik M Shah

Horace W Davenport Legacy Professor of Physiology
Professor of Molecular and Integrative Physiology
Professor of Internal Medicine
Associate Director Academic Programs, Cancer Biology Graduate Program, Medical School
headshot of Alan Smrcka

Alan Smrcka

Benedict R Lucchesi Legacy Professor of Cardiovascular Pharmacology
Professor of Pharmacology, Medical School
Professor of Biophysics, College of Literature, Science, and the Arts.
Laurie K Svoboda

Laurie K Svoboda

John G Searle Assistant Professor of Environmental Health Sciences
Assistant Professor of Environmental Health Sciences, School of Public Health
Assistant Professor of Pharmacology, Medical School
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Andrea D Thompson

Assistant Professor of Internal Medicine, Medical School
Matthias C. Truttmann

Matthias Truttmann PhD

Associate Professor of Molecular and Integrative Physiology
Research Associate Professor, Institute of Gerontology, Medical School
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Alison Vander Roest, PhD

Assistant Professor, Biomedical Engineering
Zhong Wang headshot

Zhong Wang

Professor of Cardiac Surgery, Medical School