Research | Judith Tam ALK Lung Cancer Research Initiative
Projects Powering Discovery and Innovation
At the heart of the Judith Tam ALK Lung Cancer Research Initiative is a passion for discovery and a commitment to making a meaningful impact on the lives of people affected by ALK+ lung cancer. Our research portfolio spans basic science, translational studies, and clinical innovation—each project designed to answer pressing questions, develop better therapies, and improve outcomes. Explore our active, developing, and past research projects below. Each project listing links to more detailed information, including project aims, leadership, publications, and recent news.
Browse Our Projects
Project 1
Understanding Efficacy and Resistance in ALK NSCLC Through Tumor Organoid Drug Testing and Multi-omic Integration
Project 2
Modeling and Characterizing Early ALK-dependent Tumorigenesis
Project 3
Pursuing New Approaches to Invent and Test a New Strategy for Using Combinations of Drugs Against ALK and Create Novel Inhibitors Against ALK, by Targeting a Portion of the ALK Molecule Not Usually Targeted by Conventional Therapies
Developing Projects
Explore our pipeline of developing projects—each designed to push the boundaries of understanding, prevention, detection, and treatment of lung cancer.
Past Projects
Our journey toward better lung cancer outcomes is built on a foundation of collaboration, discovery, and progress.
Our collaborators
Advancing meaningful research is a team effort, and we are deeply grateful to our valued collaborators whose expertise and partnership accelerate progress in ALK+ lung cancer research. Together, we are pushing boundaries, sharing knowledge, and making a greater impact for patients and families.
We extend special thanks to our notable collaborators:
GenPrex
Advancing novel gene therapies and translational approaches for lung cancer treatment.
Genprex is honored to have an active and productive collaboration with the Judith Tam ALK Lung Cancer Research Initiative. Through this partnership, our company has been able to conduct important and successful preclinical research that opens the door for a new clinical trial that of quaratusugene ozeplasmid (REQORSA) and seeks to offer additional treatment options for patients with ALK rearrangements.”
– Dr. Mark Berger, MD, Chief Medical Officer for Genprex
Seoul National University
Providing cutting-edge clinical insights, international collaboration, and vital tissue samples—directly supporting our work in modeling and characterizing early ALK-dependent tumorigenesis.
ALK Positive Summit
Empowering the patient community and accelerating research through advocacy, engagement, and support.
We thank each of our collaborators for their dedication and partnership. Together, we are making a real difference in the fight against ALK+ lung cancer.
News and Stories
Doctor helps one father’s race against lung cancer
ALK Positive Summit Blood Collection
$7.6 million gift launches new lung cancer research initiative at U-M
Changing the treatment of cancer