Laboratory equipment in the DCMB

4D Nucleome

4D nucleome research analyzes the 3D spatial organization of DNA, RNA, and protein in the nucleus of cells, over time (4D). This research yields further insights into the interactions among these components and how they influence various cellular behaviors, including regulation processes along the DNA-RNA-protein production chain.  

This research answers foundational questions toward a better understanding of normal and dysfunctional biological processes that lead to diseases, at the cellular level. 

This research overlaps with the study of Genomics, regulatory genomics and epigenomics and of the Application to complex genetic diseases. 

The following DCMB faculty members work in this area. 

Associated Faculty

Brian Athey

Brian D Athey, PhD

Professor
Minji Kim

Minji Kim, PhD

Assistant Professor
Jie Liu

Jie Liu, PhD

Associate Professor
Indika Rajapakse

Indika Rajapakse, PhD

Professor
Joshua Welch

Joshua Welch, PhD

Associate Professor