Genomics, Gene Regulation & Epigenomics

Regulatory genomics and epigenomics research aims to understand how the timing, quantity and variant forms of gene activity are controlled both by regulatory elements in the DNA sequences and by chemicals that bind and modify the DNA and the chromatins. The study of the genome, the regulatory genome and the epigenome together sheds light on the human genome as a dynamic system shaped by DNA sequences that is invariant in an individual’s life span and by chemical modifications through intrinsic and external factors.  

Eventually, we hope that research in these areas will uncover the secret of how the human genome defines our species, the individuals, and their health. 

DCMB faculty members’ research in these areas spans from basic science to clinical applications, as well as the development of tools and methods that enable the advancement of the field.  

This research overlaps with the study of 4D Nucleome and the Application to Complex Genetic Diseases.

The following DCMB/CCMB faculty members work in this area.