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AI & Machine Learning -
Applications to Complex Genetic Diseases -
4D Nucleome -
Genomics, Gene Regulation & Epigenomics -
Multi-“omics” Integrative Bioinformatics -
Protein Structure, Proteomics & Alternative Splicing -
Systems Biology & Networks Analysis -
Translational Bioinformatics, Drug Discovery & Pharmacogenomics -
Grants -
Software & Bioinformatics Tools
Genomics, Gene Regulation & Epigenomics
Genomics research is at the center of DCMB’s endeavor to understand the structure, function, and evolution of our genome and its role in variations of biological traits and diseases.
Regulatory genomics and epigenomics research aims to understand how the timing, quantity and variant forms of gene activity are controlled both by regulatory elements in the DNA sequences and by chemicals that bind and modify the DNA and the chromatins. The study of the genome, the regulatory genome and the epigenome together sheds light on the human genome as a dynamic system shaped by DNA sequences that is invariant in an individual’s life span and by chemical modifications through intrinsic and external factors.
Eventually, we hope that research in these areas will uncover the secret of how the human genome defines our species, the individuals, and their health.
DCMB faculty members’ research in these areas spans from basic science to clinical applications, as well as the development of tools and methods that enable the advancement of the field.
This research overlaps with the study of 4D Nucleome and the Application to Complex Genetic Diseases.
The following DCMB/CCMB faculty members work in this area.
Associated Faculty
Brian D Athey, PhD
Chair, Department of Computational Medicine and Bioinformatics
Professor of Computational Medicine and Bioinformatics
Professor of Psychiatry
Medical School
Veera Baladandayuthapani, PhD
Chair, Department of Biostatistics
Professor of Biostatistics
School of Public Health
Professor of Computational Medicine and Bioinformatics
Medical School
Kin Fai Au, PhD
Medical School
Alan P Boyle, PhD
Professor of Human Genetics
Medical School
Ivo Dinov, PhD
Professor of Nursing
Director Academic Program, School of Nursing
Professor of Computational Medicine and Bioinformatics, Medical School
Yuanfang Guan, PhD
Professor of Internal Medicine, Medical School
Jeffrey Kidd
Professor of Computational Medicine and Bioinformatics
Medical School
Minji Kim, PhD
Medical School
Jacob Kitzman, PhD
Associate Chair, Department of Human Genetics
Associate Professor of Computational Medicine and Bioinformatics
Medical School
Cong Ma, PhD
Medical School
Rajasree Menon, PhD
Computational Medicine and Bioinformatics
Medical School
Ryan Mills, PhD
Professor of Computational Medicine and Bioinformatics
Professor of Human Genetics
Medical School
Stephen CJ Parker, PhD
Professor of Human Genetics, Medical School
Professor of Biostatistics, School of Public Health
Indika Rajapakse, PhD
Professor of Mathematics, College of Literature, Science, and the Arts
Professor of Biomedical Engineering, Medical School and College of Engineering
Arvind Rao, PhD
Professor of Radiation Oncology
Medical School
Professor of Biostatistics
School of Public Health
Maureen Sartor, PhD
Bioinformatics Graduate Program
Professor of Computational Medicine and Bioinformatics
Medical School
Professor of Biostatistics
School of Public Health
Elizabeth K Speliotes, MD, PhD, MPH
Professor of Internal Medicine
Professor of Computational Medicine and Bioinformatics
Associate Director
Medical Scientist Training Program (MSTP)
Program Director
Precision Medicine Program
Medical School
Lam (Alex) C Tsoi, PhD
Associate Professor of Computational Medicine and Bioinformatics
Research Associate Professor, Mary H Weiser Food Allergy, Medical School
Research Associate Professor, Biostatistics, School of Public Health
Joshua Welch, PhD
Associate Professor of Electrical Engineering and Computer Science, College of Engineering
Yue Zhao, PhD
Computational Medicine and Bioinformatics
Medical School
