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Aerial view of U-M Health and surrounding in Ann Arbor, Michigan.

Applications to Complex Genetic Diseases

Many human diseases are linked to genetic dysfunctions. DCMB faculty collaborate with human genetics experts to:

Identify foundational knowledge gaps and develop innovative bioinformatics and computational biology theories and AI and Machine Learning methods to address these.
Test and refine existing theories and AI and Machine Learning methods in bioinformatics and computational medicine toward the study of genetic diseases.
Develop new AI and Machine Learning methods and computational tools for diagnostics and treatments.

The diseases that DCMB/CCMB faculty members study include:

Alzheimer’s Disease (Guan)
Amyotrophic Lateral Sclerosis - ALS (Boyle, Karnovsky, Sartor)
Ataxia (Burmeister)
Cancers (Baladandayuthapani, Guan, Kitzman, Omenn, Rajapakse, Sartor, Taylor)
Heart and Brain Health (Wang)
Mental disorders (Athey, Burmeister )
Metabolic diseases and obesity (Speliotes)
Renal diseases (Kretzler)
Skin diseases (Tsoi)
Substance Use Disorders - SUD (Burmeister, Athey)
Type 2 Diabetes - T2D (Parker)

This research overlaps with the study of 4D Nucleome.

Associated Faculty

Brian Athey

Brian D Athey, PhD

Professor

[email protected]

portrait of Margit Burmeister

Margit Burmeister, PhD

Professor

[email protected]

Yuanfang Guan, PhD

Professor

[email protected]

Veera Baladandayuthapani

Veera Baladandayuthapani, PhD

Professor

[email protected]

Jacob Kitzman, PhD

Professor

[email protected]

Kretzler

Matthias Kretzler, MD

Professor

[email protected]

Lara Garmire

Lana Garmire, PhD

Adjunct Associate Professor

[email protected]

Rajasree Menon, PhD

Research Scientist

[email protected]

Gilber Omenn

Gilbert S Omenn, MD, PhD

Professor

[email protected]

Steven Parker

Stephen CJ Parker, PhD

Professor

[email protected]

Indika Rajapakse, PhD

Professor

[email protected]

Maureen Sartor

Maureen Sartor, PhD

Professor

[email protected]

Elizabeth K Speliotes, MD, PhD, MPH

Professor

[email protected]

Matthew O'Meara

Matthew James O'Meara, PhD

Assistant Professor

[email protected]

Jeremy M Taylor, PhD

Professor

[email protected]

portrait of Alex Tsoi

Lam (Alex) C Tsoi, PhD

Associate Professor

[email protected]

Joshua Welch

Joshua Welch, PhD

Associate Professor

[email protected]

Yue Zhao

Yue Zhao, PhD

Research Assistant Professor

[email protected]