Pilot Projects
As we seek to understand and cure Alzheimer's disease and related dementias (ADRD), we consider it among our highest priorities to support innovative, high impact research.
This program provided “kick starter” research pilot project funds ($35,000 in direct costs) to investigators at the University of Michigan, Michigan State University, Wayne State University, and Veteran Affairs Ann Arbor Healthcare System, to test new ideas about the causes and treatment of dementing disorders.
2021 PILOT PROJECTS
Alexandru Iordan, PhD
Multimodal Investigation of Neural Plasticity Induced by Non-invasive Brain Stimulation
Ketlyne Sol, PhD
Risk and resilience mechanisms underlying race disparities in ADRD: An examination of neighborhood resources, brain integrity, and cognition
Natalie Tronson, PhD
Inflammation and the risk for cognitive decline and dementia after COVID-19
Hanna Trzeciakiewicz, PhD
Distinguishing Tauopathies by a Post-translational Modification Profile
2020 PILOT PROJECTS
Andrew Bender, PhD
White Matter Microstructure and Cognitive Plasticity: New Markers of Resilience in ADRD
DeAnnah Byrd, PhD
Cognitive Decline in African Americans: The Impact of Hypertension, Stress, and Coping
Ana M. Daugherty, PhD
Brain Iron Accumulation as a Pathway of Hypertension-Related Risk for Alzheimer’s Disease and Related Dementia
Peter Todd, PhD
Age-Associated Alterations in Protein Translation Dynamics
Omar Ahmed, PhD, University of Michigan - Understanding retrosplenial dysfunction in Alzheimer's disease to identify novel therapeutic targets
Norman Cheng, PhD, Wayne State University, and Scott Counts, PhD, Michigan State University - Magnetic properties of microvascular lesions as potential biomarkers for dementia
Benjamin Combs, PhD, Michigan State University - Mechanisms of tau-mediated retrograde transport inhibition
Patrick Pruitt, PhD, Wayne State University - Linking social isolation and cognition through functional brain network correlates in non-demented older adults
Sheria Robinson-Lane, PhD, University of Michigan - Toward a Culturally Responsive Intervention for Black Caregivers of Persons with Dementia
Benjamin Singer, PhD, University of Michigan - Amyloid potentiates neuroinflammation and cognitive decline after sepsis survival
Matthias Truttman, PhD, University of Michigan - The impact of protein AMPylation on Alzheimer’s disease
Navid Seraji-Bozorgzad, MD, University of Michigan, and Rohit Marawar, MD, Wayne State University - Cortical Microstructural Changes in African-Americans with Alzheimer’s Disease
Chandra Sripada, PhD, University of Michigan - Characterization of faster onset of Alzheimer’s disease within mild cognitive impairment patients by brain functional connectivity and genetic variants
Peter Todd, MD, PhD, University of Michigan - RNA binding protein sequestration in Non-Amyloid Dementia
Laura Zahodne, PhD, University of Michigan - Inflammation, social stress, and racial disparities in cognitive aging
Sami Barmada, MD, PhD, University of Michigan - Defining RNA-based Mechanisms of Neurodegeneration in FTLD-TDP
Jessica Damoiseaux, PhD, Wayne State University - Hippocampal Connectivity Along The Spectrum of Pre-clinical Alzheimer’s Disease
Irving Vega, PhD, Michigan State University, and Magdalena Ivanova, PhD, University of Michigan - Determine The Role of the Novel EFhd2 Protein on Tau Oligomerization
Jenna Wiens, PhD, University of Michigan - Leveraging Longitudinal Electronic Health Records for the Characterization of the Progression of Alzheimer's Disease
Benjamin Hampstead, PhD, Univeristy of Michigan - Reducing subjective memory complaints in older adults through non-invasive brain stimulation
Vikas Kotagal, MD, MS, University of Michigan - Novel approaches to measuring and facilitating the clearance of soluble amyloid from the brain
Deborah A. Levine, MD, MPH, University of Michigan - Decision Making for Cardiovascular Therapy in Adults with Mild Cognitive Impairment (MCI)
Peter K Todd, MD, PhD, University of Michigan - Screening for novel G4C2 hexanucleotide repeat expansions in neurodegenerative disease