
Supporting innovative research in cutaneous biology
The University of Michigan Skin Research Center accelerates science and innovation among the Center's members and the broader community of cutaneous researchers by supporting innovative basic research in cutaneous biology and facilitating its translation to clinical practice.
The Animal Modeling Core (AMC) provides services to help researchers design and develop genetically engineered mouse models (GEMMs). Services include resources for GEMM production, breeding, screening, validation, and the creation of primary cell cultures and cell lines. Additionally, the AMC provides services for GEMM phenotyping and in vivo manipulation, such as transgene induction and models for UV irradiation, inflammation, and fibrosis.
The Functional Analytics Core (FAC) offers advanced CRISPR/Cas9 mutagenesis services for keratinocytes, including genomic profiling and integration into a systems biology pipeline for data analysis and interpretation. the FAC provides direct access to bioinformatics analysis and large-scale genomic datasets via a web-based interface.
It is extremely important that our grant is cited in all publications resulting from the use of UM-SBDRC services and funding. Our productivity and effectiveness as a center are measured in part by the citation of the grant in published work. Please use the following acknowledgement in your publications:
This work utilized Core Services and Pilot or Feasibility project funding supported by grant UM-SBDRC 1P30AR075043 of NIH/NIAMS to the University of Michigan