Functional Analytics Core

The Functional Analytics Core (FAC) provides support and services to accelerate and enhance the effectiveness of basic and translational research in the field of cutaneous biology.

Services

We provide systems biology analyses, disease- and cytokine-specific gene expression profiling, and bioinformatics training to support skin-related research:

• Service 1: Disease case/comparison of repository genomics (Single cell RNA-seq) to aid in creating disease mouse models with bioinformatics analysis
• Service 2: Disease case/comparison of genomics in Rodent vs repository human genomics (single cell RNA-seq) to aid in creating disease mouse models with bioinformatics analysis
• Service 3: Disease case/comparison of genomics (Spatial RNA-seq) in human tissue with bioinformatics analysis
• Service 4: Disease case/comparison of genomics (Single cell RNA-seq) in human tissue and blood with bioinformatics analysis
• Service 5: Consultation with UM-SRC Functional Analytics Core
• Service 6: Protocol Development UM-SRC Functional Analytics Core

For current FAC Service Recharge rates, please email [email protected]. 

CRISPR/Cas9 Genome Editing

We provide CRISPR/Cas9 genome editing services in keratinocytes for generation of both knock-out and knock-in keratinocytes, as well as functional characterization of mutant keratinocyte lines.

Skin Genes Query

The U-M SRC Skin Genes Query supports comparison of normal and disease gene expression in human and mouse skin utilizing datasets supplied by SRC members. This tool is available to all UM-SRC members and requires University of Michigan level-1 account verification. If you are unable to access this tool and are a current UM SRC member, please email: [email protected] for assistance.

Skin Genes Query (SRC Members Only)

Contact Us

If you are interested in the FAC bioinformatics services, please email [email protected].
If you are interested in the FAC cell line services, please email [email protected].