Functional Analytics Core
Scientist discussing his research poster with a colleague

Providing innovative, state-of-the art services

The Functional Analytics Core (FAC) provides support and services to accelerate and enhance the effectiveness of basic and translational research in the field of cutaneous biology.

Services

We provide systems biology analyses, disease- and cytokine-specific gene expression profiling, and bioinformatics training to support skin-related research:

  • Service 1: Disease case/comparison of repository genomics (Single cell RNA-seq) to aid in creating disease mouse models with bioinformatics analysis
  • Service 2: Disease case/comparison of genomics in Rodent vs repository human genomics (single cell RNA-seq) to aid in creating disease mouse models with bioinformatics analysis
  • Service 3: Disease case/comparison of genomics (Spatial RNA-seq) in human tissue with bioinformatics analysis
  • Service 4: Disease case/comparison of genomics (Single cell RNA-seq) in human tissue and blood with bioinformatics analysis
  • Service 5: Consultation with UM-SRC Functional Analytics Core 
  • Service 6: Protocol Development UM-SRC Functional Analytics Core

FAC Service Recharge Rates

CRISPR/Cas9 Genome Editing

We provide CRISPR/Cas9 genome editing services in keratinocytes for generation of both knock-out and knock-in keratinocytes, as well as functional characterization of mutant keratinocyte lines.

Knockout (KO) Keratinocytes Lines Available

Skin Genes Query

The U-M SRC Skin Genes Query supports comparison of normal and disease gene expression in human and mouse skin utilizing datasets supplied by SRC members. This tool is available to all UM-SRC members and requires University of Michigan level-1 account verification. If you are unable to access this tool and are a current UM SBDRC member, please email Carmel McKeon ([email protected]) for assistance.

Skin Genes Query (SRC Members Only)

If you are interested in the FAC bioinformatics services, please email [email protected].
If you are interested in the FAC cell line services, please email [email protected]

 

Directors
Johann Gudjonsson Johann E Gudjonsson
Arthur C Curtis Professor of Skin Molecular Immunology
Professor of Dermatology
Professor of Internal Medicine and Research Professor
Mary H Weiser Food Allergy
portrait of Alex Tsoi Lam (Alex) C Tsoi, PhD
Assistant Professor of Dermatology
Assistant Professor of Computational Medicine and Bioinformatics
Research Assistant Professor, Mary H Weiser Food Allergy
Research Assistant Professor, Biostatistics
portrait of Mrinal Sarkar Mrinal K Sarkar, PhD
Assistant Research Scientist
Dermatology
Research Acknowledgement

It is extremely important that our grant is cited in all publications resulting from the use of UM-SBDRC services and funding. Our productivity and effectiveness as a center are measured in part by the citation of the grant in published work. Please use the following acknowledgement in your publications:

This work utilized Core Services and Pilot or Feasibility project funding supported by grant UM-SBDRC 1P30AR075043 of NIH/NIAMS to the University of Michigan