Research About Michigan Medicine Patient Care Research Education Departments

Clinical Studies

Make a Gift

Research & Innovation
Labs & Departments
Office of Research
Careers

Back to Main Menu Rogel Cancer Center Research Home Rogel Cancer Center Research Home
- Back to Rogel Cancer Center Research Home Research Research
  - Back to Research Basic Science Division Basic Science Division
    
    Back to Basic Science Division Signaling & Tumor Microenvironment Signaling & Tumor Microenvironment
    
    Back to Basic Science Division Cancer Genetics Cancer Genetics
    
    Back to Basic Science Division Developmental Therapeutics Developmental Therapeutics
    
    Back to Basic Science Division Hematological Malignancies Program Hematological Malignancies Program
  - Back to Research Cancer Control & Population Sciences Cancer Control & Population Sciences
  - Back to Research Translational & Clinical Research Translational & Clinical Research
  - Back to Research Clinical Research Division Clinical Research Division
  - Back to Research SPORES SPORES
    
    Back to SPORES LMS LMS
    
    Back to LMS LMS External Advisory Board LMS External Advisory Board
    
    Back to LMS LMS Funding Opportunities LMS Funding Opportunities
    
    Back to SPORES Prostate SPORE Prostate SPORE
    
    Back to Prostate SPORE Prostate Cancer SPORE Cores Prostate Cancer SPORE Cores
    
    Back to Prostate SPORE Prostate Cancer SPORE Projects Prostate Cancer SPORE Projects
    
    Back to SPORES Radiosensitization SPORE Radiosensitization SPORE
- Back to Rogel Cancer Center Research Home Patient Care Patient Care
- Back to Rogel Cancer Center Research Home Education Education
- Back to Rogel Cancer Center Research Home People People
- Back to Rogel Cancer Center Research Home Shared Resources Shared Resources
  - Back to Shared Resources Cancer Data Science Cancer Data Science
  - Back to Shared Resources Cell & Tissue Imaging Cell & Tissue Imaging
  - Back to Shared Resources Epigenetics & Epigenomics Epigenetics & Epigenomics
  - Back to Shared Resources Experimental Irradiation Experimental Irradiation
  - Back to Shared Resources Flow Cytometry Flow Cytometry
  - Back to Shared Resources Health Communications Health Communications
  - Back to Shared Resources Immune Monitoring Immune Monitoring
  - Back to Shared Resources Liquid Biopsy Liquid Biopsy
  - Back to Shared Resources Pharmacokinetics Pharmacokinetics
  - Back to Shared Resources Preclinical Molecular Imaging Preclinical Molecular Imaging
  - Back to Shared Resources Protoemics Resource Facility Protoemics Resource Facility
  - Back to Shared Resources Single Cell Spatial Analysis Single Cell Spatial Analysis
  - Back to Shared Resources Structure & Drug Screening Structure & Drug Screening
  - Back to Shared Resources Tissue & Molecular Pathology Tissue & Molecular Pathology
  - Back to Shared Resources Transgenic Animal Models Transgenic Animal Models
- Back to Rogel Cancer Center Research Home About About
  - Back to About Community Outreach & Engagement Community Outreach & Engagement
    
    Back to Community Outreach & Engagement Research Support Research Support
    
    Back to Community Outreach & Engagement Community Connections Community Connections
    
    Back to Community Outreach & Engagement Student Opportunities Student Opportunities
    
    Back to Community Outreach & Engagement Our Team & Advisors Our Team & Advisors
    
    Back to Community Outreach & Engagement Cancer 101 Cancer 101
  - Back to About Illuminate Magazine Illuminate Magazine
  - Back to About Rogel Leadership Rogel Leadership
  - Back to About Community Outreach & Engagement Community Outreach & Engagement
- Back to Rogel Cancer Center Research Home Forbes Institute for Cancer Discovery Forbes Institute for Cancer Discovery
Back to Main Menu Student Opportunities Student Opportunities

Pharmacokinetics

Gloved hand places pink colored capsules into a tray

Maize Block M Rogel Cancer Center University of Michigan Health

Advancing discovery of how the body processes drugs

The mission of the University of Michigan Rogel Cancer Center's Pharmacokinetics Shared Resource is to facilitate both preclinical and clinical pharmacokinetic-based cancer research efforts through a range of services to help advance discovery:

Discover new medicines
Obtain research funding
File patent applications
Publish academic research findings

Pharmacokinetics Objectives

Our pharmacokinetics team studies molecular ADME (absorption, distribution, metabolism, and excretion) and pharmacokinetics of drugs with three objectives:

To support preclinical pharmacokinetics, drug metabolism and LC-MS analysis for lead compound selection and dose optimization in anticancer drug discovery and development
To support clinical pharmacokinetics (Non-GLP), LC-MS analysis and dose optimization for clinical trials of anticancer drugs
To enhance joint grant applications, joint publications and joint patent applications with Rogel Cancer Center members in pharmacokinetic (PK) studies

Service Highlights

Access to state-of-the-art instrumentation for bioanalysis and MS imaging operated by highly-trained technicians
Support for drug metabolism and PK of 2600 compounds for drug discovery and development since inception
Six patents and $15M in grant funding from joint grant applications with Rogel Cancer Center members
Free consultation for Rogel Cancer Center members

If you have questions about pharmacokinetics services, please contact our team:

Director: Duxin Sun, PhD
Co-Director: Amit Pai, PharmD

Manager: Bo Wen, PhD

Location: NCRC, Bldg 520, 3400
Phone: 734-615-3470

Or visit our website