Cardiac Surgery Research

Lab googles with the Michigan block "M" sit on the table

Driving Change in Cardiovascular Care

Our dedicated team of scientists is continually advancing the field through impactful research and novel discoveries.

Decades of Discovery, Future of Promise

In the U-M Medical School Department of Cardiac Surgery, research is embedded in everything we do from the operating room to the laboratory. Researchers are actively involved in advancing the prevention, diagnosis, and treatment of cardiovascular diseases for patients of all ages. Our faculty lead groundbreaking research at every stage—from uncovering disease mechanisms to designing next-generation devices, advancing clinical trials, and evaluating healthcare delivery systems to enhance quality and efficiency. This depth of expertise is recognized nationally, with surgeons across the country turning to our team for insight and guidance on surgical techniques.

Surgeons and scientists at Michigan Medicine have long been creators and champions of new technology. This culture of innovation began decades ago with the introduction of extracorporeal membrane oxygenation, developed right here at the U-M Medical School. Since then, our department has pioneered numerous procedures, including minimally invasive valve surgery and safer methods to repair aortic aneurysms and dissections. We conduct trailblazing research that benefits both adult and pediatric patients, translating discoveries into real-world improvements in care. Michigan is also a world leader in treating hypoplastic left heart syndrome, with over 1,000 newborns cared for and mortality rates below 10%. This legacy of excellence reflects our longstanding commitment to advancing outcomes for patients of all ages with complex heart disease.

What sets our research approach apart is the close collaboration and seamless integration between researchers and clinicians, which enables us to accelerate the translation of scientific discovery into real-world patient care. Researchers in the lab work hand in hand with those performing surgery on patients—the surgeon implanting a valve is often the same person exploring how to create a valve out of a patient's own tissues. This approach facilitates bringing the newest innovations directly to patients. To support this work, we actively recruit faculty with demonstrated research skills and ensure they have the resources to be successful. As a result, the department consistently produces a high volume of influential publications across both congenital and adult cardiac care.

Areas of Research

Basic Science & Translational Research

Our researchers study the root causes of cardiovascular disease, translating benchside discoveries into bedside treatments for patients.

Clinical Research

Our clinical trials evaluate surgical advancements and treatments, bringing the latest research into the hands of care teams.

Health Services Research & Quality

Our team studies healthcare delivery and outcomes, using data-driven insights to improve quality and efficiency in cardiac surgery care.

Medical Device Innovation

Our innovators bridge clinical insight with biomedical engineering to design next-generation tools that improve patient care.

Pediatric Cardiovascular Research

Our research advances care for children with congenital heart disease, enhancing clinical outcomes and long-term quality of life.

Where Education Meets Expertise

Our research environment provides exceptional opportunities for trainees. Residents and fellows are exposed to the full scope of cardiovascular research during their time here, with some electing to spend dedicated time in clinical trials alongside their clinical patient care training. We recruit individuals with a strong interest in research and ensure they have the mentorship and resources needed to thrive. This strong foundation in research and collaboration not only benefits our trainees, it also reflects the caliber and influence of the faculty who mentor them. 

Our faculty members are frequently invited to speak at major professional meetings, both national and international, and many play key roles in professional societies and national working groups. Whether in the lab, clinic, or policy space, we are committed to driving progress that leads to better outcomes and longer, healthier lives for patients everywhere.

Close up image of a heart transplant

Cardiac Surgery by the Numbers in 2024

$6.8M
Research Funding
127
Peer-Reviewed Publications
56
Active Clinical Trials

Featured News & Stories

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Man on the left in a hospital bed with his thumb up. Man on the right is standing next to a motorcycle wearing a suit and a helmet.
Health Lab

Texas man walking on ‘new legs’ after complex vascular procedures

A Texas man walks five miles daily on “new legs” after undergoing a minimally invasive vascular procedure at University of Michigan to restore blood flow to blocked vessels.
doctor in white coat with heart model in hand in hallway looking down
Health Lab

How a temporary heart pump can support high risk cardiac surgery

A cardiac surgeon from Michigan Medicine offers helpful details on Impella devices.
grandma with baby in arms smiling
Health Lab

Treating a rare coronary artery aneurysm without open heart surgery

Cardiologists at University of Michigan Health prevented the rupture of an aneurysm in a woman’s heart and used a minimally invasive solution to avoid open heart surgery. 
A woman stands in a plaid sweater over a red shirt with a cross necklace on the left. On the right, a woman in a hospital gown poses for a photo by the window with two people.
Health Lab

Fighting rejection antibodies to make heart transplant possible

A woman who spent more than a decade with life-threatening heart rhythms received a transplant despite having high levels of antibodies that reject donor organs.
Members of Eugene Chen's laboratory with a basketball
News Release

A night of two national titles for U-M, as scientists and basketball players both triumph

On the same night that the U-M men's basketball team triumphed in the NCAA tournament, U-M cardiovascular researchers won a national tournament of science
surgeons up close in surgery with scrubs and scrub hats on green teal
Health Lab

Failed TAVR? Heart surgeons explain TAVR explant, options and risks

As transcatheter aortic valve replacement, or TAVR, gains popularity, cardiac surgeons are seeing more cases of failing valves. Two cardiac surgeons from Michigan Medicine explain TAVR explant and other surgical options.