T32 Pharmacological Sciences Training Program (PSTP)
The Pharmacological Sciences Training Program (PSTP) is a unique collaboration between the Medical School and the College of Pharmacy that provides synergistic, translational education, research training, and career development with the ultimate goal of preparing our graduates to excel as leaders in the field of experimental therapeutics, both in the academy and in the private sector.
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Program Overview
PSTP trainees will develop a strong foundation in basic principles of pharmacology and medicinal chemistry and a broad knowledge of other related basic science disciplines including biochemistry, chemistry, and physiology so that they can ultimately direct cutting-edge research in pharmacology and therapeutics and address scientific questions from multiple perspectives.
Trainee activities include participation in: joint seminars, the annual PSTP Symposium, semi-annual Pharmacology and Experimental Therapeutics Career Day, College of Pharmacy Career and Networking Events. All trainees complete a core curriculum in pharmacological sciences consisting of courses in pharmacology, medicinal chemistry, statistical analysis, and grant-writing and scientific communication; with other courses designed to fit the programmatic needs of individual students and the degree requirements of the individual departments.
Participating Programs
PSTP Faculty
PSTP Trainees & Recent Alumni
2025 Cohort
Avery Campbell
Pharmacology PhD Trainee
Ruas Lab
Gracie Kmiec
Pharmacology PhD Trainee
Jenkins Lab
Jimena Alvarez-Castanon
Pharmacology PhD Trainee
Lorberbaum Lab
Olivia Kohler
Biological Chemistry PhD Trainee
E. Scott Lab
Alyssa Rodriguez
Medicinal Chemistry PhD Trainee
Balunas Lab
Vincent Cicale
Pharmaceutical Sciences PhD Student
Bordeau Lab
2024 Cohort
Alex Powell
Pharmacology PhD Student
Traynor Lab
Erika Ruskie
Pharmacology PhD Student
Hastings and Scott Labs
Tyler Brant
Biological Chemistry PhD Student
Sherman Lab
Ashley Scheutzow
Biological Chemistry PhD Student
Baldridge Lab
Sierra Hefferan
Medicinal Chemistry PhD Student
Sherman Lab
Katherine Hoegeman
Medicinal Chemistry PhD Student
Clasby Lab
Ryan Russo
Medicinal Chemistry PhD Student
Narayan Lab
Helen SaTsu
Medicinal Chemistry PhD Student
Hastings Lab
Hannah Myatt
Pharmaceutical Sciences PhD Student
Sun Lab
2023 Cohort
Kalynn Bird
Pharmacology PhD Student
Jenkins Lab
Kaitlyn Digsby
Pharmacology PhD Student
J Miller/Brody Lab
Krystal Santiago Colon
Pharmacology PhD Student
Mattis/Isom Lab
Hannah Boesger
Medicinal Chemistry PhD Student
Sherman Lab
Julia Catalano
Pharmaceutical Sciences PhD Student
Schwendeman Lab
Vishakha Choudhary
Biological Chemistry PhD Student
Smith Lab
2022 Cohort
Jeremy Dortch
Biological Chemistry PhD Student
Baldridge Lab
Behirda Karaj
Pharmacology PhD Student
Brenner Lab
Cristian Martinez-Ramos
Pharmacology PhD Student
Osawa Lab
Kathryn Hoegeman
Medicinal Chemistry PhD Student
Clasby lab
2022 Cohort
Derrick Ousley, PhD,
Thesis: “Genome and Transcriptome Mining of Macrocyclic Plant Peptide Natural Products for Multi-omics guided Drug Discovery”
Advisor: Roland Kersten, PhD
Mariana Romero-Gonzalez, PhD,
Thesis: “Mechanistically Guided Design of an Inhaled Synergistic Antibiotic Combination Therapy”
Advisor: Ashlee Brunaugh, PhD
Livia Stanger, PhD, Associate Consultant, ZS
Thesis: “Antithrombotic Therapies: Targeting Novel Approaches to Improve the Treatment of Cardiovascular Disease”
Advisor: Mike Holinstat, PhD
2021 Cohort
Adam Ard, PhD, Postdoctoral Research at University of Michigan
Thesis: ”Discovery and SAR-Guided Development of Small-Molecule SERCA2a Activators for Cardiovascular Applications”
Advisor: Martin Clasby
Adaeze Eneli, PhD, Postdoctoral Research Fellow at University of Michigan
Thesis: “Understanding the Critical Quality Attributes Influencing Doxil? Performance In Vitro and In Vivo”
Advisor: Anne Schwendeman, PhD
Kassidy Jungles, PhD, Medical Writer, Precision AQ
Thesis: ”The Implementation of Combination Therapies for the Treatment of Triple Negative Breast Cancer (TNBC)”
Advisor: James Rae, PhD
Sophia Meyer, PhD, Principal Scientist at Intero Biosystems
Thesis: ”Single-Cell Multiplexed Imaging to Enhance Prediction, Detection, and Mechanistic Understanding of Drug Efficacy and Toxicity in Hepatic and Intestinal Systems”
Advisor: Jonathan Sexton, PhD
Tenzin Ngodup, PhD, Postdoctoral Fellow
Thesis: “Role of Hypoxia in Fibroblast Reprogramming in Pancreatic Cancer”
Advisor: Kyoung Lee, PhD
Claire Shudde, PhD, Postdoctoral Fellow at Oklahoma Medical Research Foundation
Thesis: ”Cytokine-Independent Activation of STAT5 Promotes the Persistence and Function of CD4+ Regulatory T Cells”
Advisor: Adam Courtney, PhD
2020 Cohort
Shreeya Bakshi, PhD, Postdoctoral Researcher at University of Michigan
Thesis: “Better Retained than Forgotten: Investigation of SCN1B intron 3 Retention and Its Link to Developmental and Epileptic Encephalopathy”
Advisor: Lori Isom, PhD
Elyse Frydendall, PhD, Consultant, Boston Consulting Group
Thesis: “Human Cytochrome P450 Enzymes in Drug and Fatty Acid Metabolism”
Advisor: Emily Scott, Ph.D.
Natalia Harris, PhD, Postdoctoral Researcher at University of Michigan
Thesis:’ Enzymatic and Structure-Guided Diversification of Nitrogen-Containing Heterocycles from Natural Products for Therapeutic Applications”
Advisor: David Sherman, PhD and Janet Smith, PhD
Emily Makowski, PhD, Senior Scientist, Genentech
Thesis: "Multi-Objective Engineering of Therapeutic Antibodies"
Advisor: Peter Tessier, PhD
Francisco Sanchez-Conde, PhD, Consultant, Trinity Life Sciences
Thesis: ”hERG1 Nuclear Peptide: Probing a Novel hERG1 Subdomain as a Mechanism of Sudden Death Syndromes”
Advisor: David K. Jones, PhD
Glory Velazquez, PhD, Adjunct Chemistry Professor, Ana G. Mendez University
Thesis: “Antibiotic Discovery of Inhibitors of Transcription Factors-RNA Polymerase Protein-Protein Interactions in Mycobacterium tuberculosis”
Advisor: George Garcia, PhD
2019 Cohort
Kristen Hong Dorsey, PhD, Advisor, Eli Lilly and Company
Thesis: "Evaluation of Lipid-Based Nanoparticles for the Treatment of Cardiovascular Diseases"
Advisor: Anna Schwendeman, PhD
Jesse Wotring, PhD, Medicinal Chemist
Thesis: "Rapidly Translational Drug Discovery Using High Content Imaging: Applications to Non-Alcoholic Fatty Liver Disease and the COVID-19 Pandemic"
Advisor: Jonathan Sexton, PhD
Chi-Chi Ukachukwu, PhD, Eli Lilly and Company
Thesis: "The hERG1 PAS Domain: An Anti-arrhythmic Drug Target and Master Regulator of IKr"
Advisor: David K. Jones
Kelsey Kochan, PhD, FDA Pharmacologist
Thesis: "Characterization of Positive Allosteric Modulators of the Mu Opioid Receptor"
Advisor: John Traynor, PhD
2018 Cohort
Josh Lott, PhD, Medical Science Liaison, Merz Aesthetics
Thesis: "Delineating the Specificity of Cannabinoid Effects by Investigating Cannabinoid Receptor-1 Trafficking and Signaling"
Advisor: Manoj Puthenveedu, PhD
Alina Morales, Scientific Associate, Viscira
Thesis: "Regulation of Chromaffin Cell Exocytosis via Endogenously Secreted Signaling Molecules Acetylcholine and PACAP"
Advisor: Arun Anantharam, PhD
Andrea Pesch, PhD, Sr Regulatory Affairs Specialist, Loxo Onocology
Thesis: "Targeting DNA Damage, Apoptosis, and the Cell Cycle for the Radiosensitization of Aggressive Forms of Breast Cancer"
Advisors: Corey Speers, MD, PhD and James Rae, PhD
Garrett Dow, PhD, Senior Development Scientist, Beckman Coulter
Thesis: "Elucidation of DNA-Binding and Dimerization Activities of the Master Virulence Transcription Factor, VirF, From Shigella flexneri to Aid in Virulence-Targeted Inhibitor Design for Treatment of Shigellosis"
Advisor: George Garcia
Jennifer Diaz-Espinosa, PhD, Advisor, Eli Lilly and Company
Thesis: "Mechanistic Analysis and Quantification of Clofazimine"
Advisors: Kathleen Stringer, Ph.D. and Haojie Zhu, PhD
Rachel Torrez, PhD, Postdoctoral Scholar, Univ of Utah
Thesis: "Structural and Functional Analysis of Human Dicer"
Advisors: Amanda Garner, Ph.D. and Melanie Ohi, PhD
2017 Cohort
Jason Albert, PhD, Presidential Management Fellow | Dept. of Energy
Thesis: "Metal-HisTag Coordination for Remote Loading of Biomacromolecules into PLGA Microspheres"
Advisor: Steven Schwendeman, PhD
Sarah Burris, PhD, Postdoctoral Researcher University of Michigan
Thesis: "Human Cytochrome P450 Enzymes in Steroidogenesis and Drug Metabolism"
Advisor: Emily Scott, Ph.D.
Nnamdi Edokobi, PhD, Scientist | Choate, Hall & Stewart LLP
Thesis: "The Role of Voltage-Gated Sodium Channel Gene Scn1b in the developing pediatric heart"
Advisor: Lori L. Isom, PhD
Julie Philippe Gupta, PhD, Life Sciences Consultant, Putnam Associates
Thesis: "Ankyrin-B is Lipid-Modified by S-Palmitoylation to Promote Dendritic Membrane Scaffolding of Voltage Gated Sodium Channel Nav1.2 in Neurons"
Advisor: Paul Jenkins, PhD
PSTP Executive Committee
Lori L Isom, PhD
Chair, Department of Pharmacology
Professor of Pharmacology
Professor of Molecular and Integrative Physiology
Professor of Neurology
Medical School
Paul M Jenkins
Associate Professor of Pharmacology
Associate Professor of Psychiatry and Associate Chair for Education
Department of Pharmacology
Medical School
David H Sherman, PhD
Professor of Medicinal Chemistry, College of Pharmacy
Professor of Microbiology and Immunology, Medical School
Professor of Chemistry, College of Literature, Science, and the Arts
Research Professor, Life Sciences Institute
Patrick O'Brien
Department of Biological Chemistry
Professor of Biological Chemistry
Medical School
Nouri Neamati, PhD
Program Representative- Medicinal Chemistry